Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California

 

Recent News and Articles on the Keywords: alzheimers + people + pet  Related to the article below (Last Update: 8/5/2008)

New chemical may help scan brain for signs of Alzheimer?s
Schenectady Gazette, NY -
?Traditionally, PET scanning shows changes in Alzheimer?s disease after the damage to the metabolism has already occurred,? Holub explained. ...

China Daily
Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show ...
FOXBusiness - Jul 30, 2008
Each participant received a single intravenous injection of one of the compounds followed by PET imaging. People with Alzheimer's showed retention of all ...
Drug could prevent long-term memory loss in Alzheimer's patients Nursing Times
Alzheimer's drug 'could reduce mild memory loss' Craegmoor News
Spinal fluid marker tracks brain amyloid, may identify Alzheimer's ... Medicexchange
SunHerald.com
all 678 news articles »
Maternal link to Alzheimer's suggested
United Press International -
This lack of ability for the brain to use glucose efficiently seen in those whose mothers had Alzheimer's may predispose such people to Alzheimer's disease. ...
Advanced Medical Isotope Corporation Delivers Initial Shipment of ...
MarketWatch - 25 minutes ago
FDG is being utilized for a variety of purposes, including diagnosis and monitoring the treatment of Hodgkin's disease, non-Hodgkin's lymphoma, Alzheimer's ...

TopNews
Moms With Alzheimer's May Pass on Risk to Kids
Washington Post, United States - Jul 30, 2008
By Steven Reinberg WEDNESDAY, July 30 (HealthDay News) -- People whose mothers have had Alzheimer's disease may be predisposed to the mind-robbing condition ...
Mom's Alzheimer's May Raise Children's Risk WebMD
Children of Alzheimer's-stricken Mothers Face Higher Risk TheMedGuru
Digestion Of Harmful Protein Oneindia
HealthCentral.com - Science Daily (press release)
all 46 news articles »
'Biomarkers' May Help Spot, Track Alzheimer's
U.S. News & World Report, DC - Jul 29, 2008
... allowed researchers to distinguish between people with Alzheimer's, people with Parkinson's-related dementia and those who were cognitively normal. ...
Alzheimer's Drug May Help Mild Memory Loss, Imaging Study Suggests
Science Daily (press release) - Jul 30, 2008
Both groups underwent PET brain scans before and after 18 months of treatment. The brains of people given Aricept showed an increased rate of metabolism and ...
Alzheimer Disease Plaques Seen With Conventional MRI in Animal ...
MarketWatch - Jul 27, 2008
The ability to non-invasively show amyloid plaque levels in living people could markedly improve the diagnosis and treatment of people with Alzheimer's. ...
Four Alzheimer's Clinical Trials Address a Variety of Treatment ...
FOXBusiness - Jul 30, 2008
Another objective was to determine MTC's potential to modify the course of Alzheimer's over 19 months. Imaging results from SPECT and PET scans were ...
Avid Radiopharmaceuticals Presents Clinical Results of Novel ...
MarketWatch - Jul 29, 2008
Avid is currently enrolling patients in clinical studies of (18)F-PET agents for imaging amyloid plaques in Alzheimer's disease and for imaging the ...
Source: Google News

… a therapy dog to alleviate the agitation and desocialization of people with Alzheimer's disease. -
M Churchill, J Safaoui, BW McCabe, MM Baun - J Psychosoc Nurs Ment Health Serv, 1999 - ncbi.nlm.nih.gov
Using a therapy dog to alleviate the agitation and desocialization of people with
Alzheimer's disease. Churchill M, Safaoui J, McCabe BW, Baun MM. ...

PET imaging of amyloid in Alzheimer's disease -
A Nordberg - Lancet Neurology, 2004 - Elsevier
... Alzheimer's disease (AD) is the most common form of dementia ... of patients with AD
than in those of healthy people. ... that are suitable not only for PET but also ...

Specificity of Brain Activation Patterns in People at Genetic Risk for Alzheimer Disease -
AC Burggren, GW Small, FW Sabb, SY Bookheimer - ajgp, 2002 - Am Assoc Geria Psych
... R, Barker W, Pascal S, et al: Behavioral-activation PET studies in ... Cohen MS, et al:
Patterns of brain activation in people at risk for Alzheimer's disease ...

Animal-Assisted Therapy and Nutrition in Alzheimer's Disease -
NE Edwards, AM Beck - Western Journal of Nursing Research, 2002 - wjn.sagepub.com
... Journal of the American Animal Hospital Association, 25 ... environmental press and the
adaptation of older people. ... with senile dementia of the Alzheimer?s type. ...

The US economic and social costs of Alzheimer's disease revisited -
RL Ernst - American Journal of Public Health, 1994 - Am Public Health Assoc
... of a specialized care center for people with Alzheimer's ... and F. Forette Patients
with Alzheimer's Disease Living at ... GS Gazelle Cost-Effectiveness of PET in the ...

Early Detection of Alzheimer's Disease by Combining Apolipoprotein E and Neuroimaging a -
GW SMALL, S KOMO, ALA RUE, S SAXENA, ME PHELPS, JC … - Annals of the New York Academy of Sciences, 1996 - Blackwell Synergy
... APOLIPOPROTEIN E AND ALZHEIMER?S DISEASE 73 ... People with age-related mild memory
complaints were studied with functional (FDG-PET) and neuropsychological ...

Making sense of the stories that people with Alzheimer's tell: a journey with my mother -
J Crisp - Nursing Inquiry, 1995 - Blackwell Synergy
... and Todorov.*l Indeed, since people with Alzheimer?s continue ... a dangerous hot pool
in which many people are getting ... can?t sing; a much loved pet dies and ...

Resident Dog in the Alzheimer's Special Care Unit -
BW McCabe, MM Baun, D Speich, S Agrawal - Western Journal of Nursing Research, 2002 - wjn.sagepub.com
... MM (1999). Using a therapy dog to allevi- ate the agitation and
desocialization of people with Alzheimer?s Disease. Journal of ...

[PDF] Early detection of Alzheimer?s disease: An fMRI marker for people at risk -
AD Wagner - Nature Neuroscience, 2000 - mit.edu
... so preclinical discrimination between people who will ... to pre- clinical detection
of Alzheimer?s disease ... positron emission tomog- raphy (PET) reveals decreased ...
-

Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy …
M Iyo, H Namba, K Fukushi, H Shinotoh, S Nagatsuka … - Lancet, 1997 - ncbi.nlm.nih.gov
... cerebral cortex of patients with Alzheimer's disease. ... activity in the brains of living
people. METHODS: Positron emission tomography (PET) and a radiolabelled ...

Source: Google Scholar
 
 

Detect brain differences in people at risk for Alzheimer's using PET Scans

Article continues below and (thank you)
 
Using brain imaging, researchers at Columbia University Medical Center (CUMC) have found clear differences in brain function between healthy people who carry a genetic risk factor for Alzheimer's disease and those who lack the factor.

Because researchers believe that Alzheimer's disease starts changing the brain years before any symptoms appear, the disease may be most amenable to treatment in these pre-clinical stages. If so, detecting the early changes will be crucial for future therapies.

People who carry the genetic risk factor, the å 4 allele of the Apolipoprotein (APOE) gene, have higher risk of developing the disease than non-carriers and usually show symptoms earlier.

"It is possible that what we're seeing in the APOE- å4 carriers are early changes in the brain caused by Alzheimer's disease," says the study's senior author, Yaakov Stern, Ph.D., of CUMC's Taub Institute and Sergievsky Center.

But he and the study's first author, Nikolaos Scarmeas, M.D., caution that more research is needed before it's known for certain if the difference is an early sign of Alzheimer's. "It's also possible that the brain differences we see are related to the APOE gene but are not necessarily directly related to incipient Alzheimer's," says Dr. Scarmeas, a neurologist in the Taub Institute, Sergievsky Center and neurology department. "Even so, the differences we've found may provide information on how the å4 allele predisposes carriers to Alzheimer's disease."

The present study appears in the Nov.-Dec. 2004 issue of the American Journal of Geriatric Psychiatry.

About the Study

The researchers looked at six people who carried the APOE- å4 risk factor and 26 non-carriers.

None of the 32 participants, mostly in their 60s and 70s, had any signs of dementia or memory deficits and the two groups could not be distinguished from one another by standard cognitive tests.

PET scans taken while the subjects were performing a memory task, however, showed clear differences between the two groups. As the participants tried to remember if they'd seen a particular shape before, one pattern of brain activation appeared in the APOE- å4 carriers while a different pattern appeared in the non-carriers.

Dr. Scarmeas says the difference may indicate that APOE- å4 carriers have to compensate for early damage done by Alzheimer's by switching to an alternate brain network to complete the task. It could also be that their different genetic makeup results in different patterns of brain activity.

In previous studies, Dr Scarmeas has demonstrated APOE-related changes in brain activity in patients that already have Alzheimer's disease and in healthy, young, college-age people. Drs Scarmeas, Stern and a large group of other researchers at the Taub Institute are using advanced brain imaging techniques to examine changes in cognition and brain function as a result of normal aging and brain diseases, such as Alzheimer's disease.

Columbia University Medical Center provides international leadership in basic and clinical research, medical education, and health care. The medical center includes the dedicated work of many physicians, scientists, and other health professionals at the College of Physicians & Surgeons, the School of Dental & Oral Surgery, the School of Nursing, the Mailman School of Public Health, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. The pioneering achievements of Columbia University health scientists, who contributed some of the 20th century's most significant medical breakthroughs, continue today.

Contact: Karen Zipern
kz2110@columbia.edu
212-305-9746
Columbia University College of Physicians and Surgeons
 
 
 
Google
Web www.iconocast.com
 
 
 

 

Continue News With: News2 ; News3 ; News4 ; News5 ; News6 ; News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services. Home

 © 2002-2006

Keywords::

Contact Iconocast

Home Page