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Recent News and Articles on the Keywords: breast cancer + breast + cancer  Related to the article below (Last Update: 8/5/2008)


Ottawa Citizen
Christina Applegate fighting breast cancer
RTE.ie, Ireland -
Emmy award-winning actress Christina Applegate is undergoing treatment for breast cancer, her publicist has revealed. Applegate, who is best known for her ...
AssociatedPress
Breast cancer diagnosis ... and the outcome Los Angeles Times
How MRI Scans Find Breast Cancers Like Christina Applegate's U.S. News & World Report
National Post - Winnipeg Sun
all 991 news articles »
Environment and Breast Cancer Support in the Bag
MarketWatch -
Being aware and understanding breast cancer and its impact on individuals, families, and society as a whole is a key mission of the National Breast Cancer ...
UA study: Woman's bone density may predict breast cancer risk
Tucson Citizen, AZ -
Bone density screenings, most commonly used to detect osteoporosis, may also be helpful in determining a woman's risk for developing breast cancer, ...
Biovest Joins in the Formation of the Joint US-Norway Cancer ...
MarketWatch - 40 minutes ago
... and to create vaccines and other cancer related therapies for various types of cancer including breast cancer, ovarian cancer, and colon cancer. ...OTC:BVTI

BBC News
People in the News: Applegate fighting breast cancer
Seattle Post Intelligencer - Aug 3, 2008
Christina Applegate is undergoing treatment for breast cancer, but the disease was caught early and the actress is expected to fully recover, her publicist ...
Chief chat Louisville Courier-Journal
all 1,282 news articles »
Breast Cancer Awareness Lifted to New Heights
Utility Products Magazine, OK - 42 minutes ago
Seeing this as a worthwhile cause, they decided to create a breast cancer awareness campaign by purchasing two "special" JLG Model 800S telescoping boom ...
Early screening is crucial to improving recovery rates for breast ...
Orlando Sentinel, FL -
"As you age, your risk of developing breast cancer increases," says Dr. Nikita Shah, director of the breast-cancer unit at MD Anderson Cancer Center Orlando ...
Does aluminum cause Alzheimer's or breast cancer?
Bradenton Herald,  United States -
By JOE GRAEDON I have heard about a link between aluminum in antiperspirants and breast cancer. I have also read that aluminum may be associated with ...

The Associated Press
Christina Applegate treated for breast cancer
The Associated Press - Aug 4, 2008
LOS ANGELES (AP) ? Christina Applegate is undergoing treatment for breast cancer, but the disease was caught early and the actress is expected to fully ...

Canada.com
Genetic discovery may lead to blood test for families with high ...
The Canadian Press, TORONTO -
Her mother died of breast cancer at 35 when she was six, following the death of her mother's twin sister from the same malignancy. ...
Genetic discovery offers hope to family with legacy of cancer Canada.com
Genetic discovery may lead to new blood test for people at high ... Canada NewsWire (press release)
Genetic Anomaly Discovered, Early Blood Test Could Detect Tumors AHN
Canada NewsWire (press release)
all 62 news articles »
Source: Google News

… for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project … -
B Fisher - J Natl Cancer I, 1998 - jnci.oxfordjournals.org
... ARTICLES. Tamoxifen for Prevention of Breast Cancer: Report of the National
Surgical Adjuvant Breast and Bowel Project P-1 Study. ...

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu … -
DJ Slamon, GM Clark, SG Wong, WJ Levin, A Ullrich, … - Science, 1987 - sciencemag.org
... Science articles. Human breast cancer: correlation of relapse and survival
with amplification of the HER-2/neu oncogene. DJ Slamon ...

… plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2 -
DJ Slamon, B Leyland-Jones, S Shak, H Fuchs, V … - New England Journal of Medicine, 2001 - content.nejm.org
Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast
Cancer That Overexpresses HER2. ... Adjuvant trastuzumab for breast cancer. ...

Gene expression profiling predicts clinical outcome of breast cancer -
LJ van't Veer, H Dai, MJ van de Vijver, YD He, AAM … - Nature, 2002 - Mass Med Soc
... Gene "Fingerprint" Improves Prognostic Accuracy in Breast Cancer. ... van 't Veer LJ
et al. Gene expression profiling predicts clinical outcome of breast cancer. ...

An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families -
SA Narod, D Ford, P Devilee, RB Barkardottir, HT … - Am J Hum Genet, 1995 - pubmedcentral.nih.gov
... These families contain either a total of three or more cases of early-onset
(before age 60 years) breast cancer or ovarian cancer. ...

Lymphatic mapping and sentinel lymphadenectomy for breast cancer. -
AE Giuliano, DM Kirgan, JM Guenther, DL Morton - Annals of Surgery, 1994 - pubmedcentral.nih.gov
... Copyright notice. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. ...
Controversies in primary breast cancer management. Am J Surg. ...

The effect of raloxifene on risk of breast cancer in postmenopausal women -
SR Cummings, S Eckert, KA Krueger, D Grady, TJ … - feedback, 2005 - biomedcentral.com
... Paper Report. The effect of raloxifene on risk of breast cancer in postmenopausal
women SR Cummings, S Eckert, KA Krueger, D Grady, TJ Powles, JA Cauley, L ...

Projecting Individualized Probabilities of Developing Breast Cancer for White Females Who Are Being … -
MH Gail, LA Brinton, DP Byar, DK Corle, SB Green, … - jnci, 1989 - jnci.oxfordjournals.org
... Press Projecting Individualized Probabilities of Developing Breast Cancer
for White Females Who Are Being Examined Annually. Mitchell ...

… antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after … -
MA Cobleigh, CL Vogel, D Tripathy - feedback, 2005 - biomedcentral.com
... study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women
who have HER2-overexpressing metastatic breast cancer that has progressed ...

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer -
MJ van de Vijver, YD He, LJ van't Veer, H Dai, AAM … - New England Journal of Medicine, 2002 - content.nejm.org
A Gene-Expression Signature as a Predictor of Survival in Breast Cancer. Marc J.
van de Vijver, MD, Ph.D., Yudong D. He, Ph.D., Laura J. van 't Veer, Ph.D ...

Source: Google Scholar
 
 

MRI Can Help Predict Breast Cancer Recurrence

Article continues below and (thank you)
 
MRI measurement of breast tumor volume - before, during and after chemotherapy - can help predict whether a patient's cancer will return, a new study shows.

The study, performed at the University of California-San Francisco, of 58 breast cancer patients found that the best way to predict a patient's recurrence-free survival is to review the initial MR examination (before the patient has chemotherapy) and the final MR examination (after chemotherapy has been completed). “Initial tumor volume was a strong predictor of recurrence free survival. Of the women who had tumor volumes of 33 cm3 or less on the initial MR exam, 93% remained disease free after two years, compared with 70% of the women with larger tumors. This speaks strongly for the value of early detection,” said Savannah C. Partridge, PhD, now an assistant professor of radiology at the University of Washington, Seattle.

“The change in tumor volume with treatment was also a valuable predictor,” said Dr. Partridge. “We found that the group of patients who had a 50% or greater reduction in MRI tumor volume when comparing the first MR examination to the last had a better recurrence-free survival rate (87% remained disease-free after two years) than those with less tumor shrinkage during chemotherapy treatment (64% were disease-free after two years), irrespective of their initial tumor volumes,” she added.

One patient with a large focal mass showed a substantial decrease in tumor volume on MRI during treatment, and continues to be disease-free 40 months after surgery. In contrast, a second patient, with a more diffuse mass, showed an increase in tumor volume on MRI during treatment that was not detected by clinical examination. Her disease returned eight months after surgery, said Dr. Partridge.

Most often, MRI is used to measure the tumor's diameter, said Dr. Partridge. “This study shows that while measuring tumor diameter is useful for staging, volume is preferable for monitoring treatment because 3D volume measurements can more accurately capture the extent of irregularly shaped tumors, multifocality and diffuse shrinkage of lesions during treatment,” she said. “It is important that an accurate and validated tool be used for calculation of 3D tumor volume from MRI images,” she noted.

Physicians now typically evaluate treatment response by clinical exam and pathology. “But unlike pathology, early changes in tumor volume can potentially be assessed by MRI at a time when chemotherapy regimens can still be modified. Our study showed that MRI measurements of breast tumor volume can help predict recurrence-free survival. We are encouraged by these results and anticipate that monitoring tumor response by MRI will help us to better tailor treatment strategies for individual patients. A larger multi-center study is currently underway to see if MRI can determine if chemotherapy is working early enough for treatment to be changed,” she said.

The study appears in the June 2005 issue of the American Journal of Roentgenology.

A PDF of the study is available upon request to reporters.

AJR Jun 2005;184:1774-1781

The American Journal of Roentgenology (AJR) is a highly respected peer-reviewed monthly radiology journal published by the American Roentgen Ray Society (ARRS). For almost 100 years, the AJR has been recognized as one of the best specialty journals in the world. The ARRS and AJR are named after Wilhelm Röentgen, who discovered the x-ray in 1895. For more information, visit http://www.arrs.org .

Contact: Jason Ocker
jason@arrs.org
703-858-4304
American Roentgen Ray Society
http://www.arrs.org
 
 
 
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