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Recent News and Articles on the Keywords: multiple + 0.53 + sclerosis  Related to the article below (Last Update: 8/5/2008)

Genzyme Reports Strong Second-Quarter Growth
FOXBusiness - Jul 23, 2008
Genzyme continued to enroll patients in two ongoing Phase 3 trials of alemtuzumab for the treatment of multiple sclerosis. Final, three-year efficacy and ...GENZ - OTC:CMTX
Source: Google News

THE NATURAL HISTORY OF MULTIPLE SCLEROSIS: A GEOGRAPHICALLY BASED STUDY: 4. APPLICATIONS TO PLANNING … -
BG WEINSHENKER, GPA RICE, JH NOSEWORTHY, W … - Brain, 1991 - Oxford Univ Press
... randomized clinical therapeutic trials of immunosuppressants and other agents in
multiple sclerosis (MS) complicates ... 0.18 0.19 0.17 0.08 0.09 0.24 0.53 0.43 0 ...

Mortality from multiple sclerosis and exposure to residential and occupational solar radiation: a … -
DM Freedman, M Dosemeci, MCR Alavanja - Occupational & Environmental Medicine, 2000 - pt.wkhealth.com
... skin cancer, mortality from multiple sclerosis was negatively associated with
residential exposure to sunlight (odds ratio (OR)=0.53 (multiple sclerosis) and ...

Multiple sclerosis: updated risks -
AD Sadovnick, PA Baird, RH Ward - Am J Med Genet, 1988 - doi.wiley.com
... Multiple sclerosis (MS) is the most common cause of neurological disability affecting
young adults. ... Maternal first cousin 21377 0.53 f 0.37 0.89 2 0.63 ...

Brain atrophy in clinically early relapsing-remitting multiple sclerosis. -
DT Chard, CM Griffin, GJM Parker, R Kapoor, AJ … - Brain, 2002 - pt.wkhealth.com
... atrophy and lesions in a cohort with relapsing-remitting multiple sclerosis and
a ... and T 2 load correlated equally with corpus callosum area (r=-0.53, P < 0.001 ...

Epidemiology of multiple sclerosis in US veterans: 1. Race, sex, and geographic distribution -
JF Kurtzke - Neurology, 1979 - AAN Enterprises
... who have been compensated by the Veterans Administration for multiple sclerosis
(MS) were ... and both sexes, case/control ratios were 1.41, 1.00, and 0.53 for the ...

A longitudinal study of brain atrophy in relapsing multiple sclerosis -
JH Simon, LD Jacobs, MK Campion, RA Rudick, DL … - Neurology, 1999 - AAN Enterprises
... and placebo-treated) from the phase III Multiple Sclerosis Collaborative Research ...
between third ventricle and lateral ventricle width (r = 0.53, p = 0.0001). ...

Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis. -
M Filippi, M Bozzali, M Rovaris, O Gonen, C … - Brain, 2003 - pt.wkhealth.com
... error 0.67 mM) and without (mean 10.39 mM, standard error 0.53 mM) enhancing ... axonal
pathology is an early event in the course of multiple sclerosis and fits ...

Vitamin D intake and incidence of multiple sclerosis -
KL Munger, SM Zhang, EO'Reilly, MA Hernan, MJ Olek … - Neurology, 2004 - AAN Enterprises
... The incidence of multiple sclerosis (MS) is low in the tropics and increases with
distance ... vitamin D intakes were 0.52 (p for trend = 0.004) and 0.53 (p for ...

… in patients with mildly disabling relapsing-remitting multiple sclerosis: an exploratory study with … -
M Rovaris, G Iannucci, M Falautano, F Possa, V … - J Neurol Sci, 2002 - ncbi.nlm.nih.gov
... resonance imaging (MRI) correlates of cognitive dysfunction in multiple sclerosis
(MS) achieved ... NAWM and NAGM values (r values ranging from -0.30 to -0.53). ...

Association between stressful life events and exacerbation in multiple sclerosis: a meta-analysis -
DC Mohr, SL Hart, L Julian, D Cox, D Pelletier - BMJ, 2004 - pubmedcentral.nih.gov
... studies, our results support the hypothesis that stress is related to exacerbation
of multiple sclerosis, with a weighted average effect size of d = 0.53. ...

Source: Google Scholar
 
 

Human Exposure To Aluminium And Multiple Sclerosis Link, Keele University

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Scientists at Keele University in Staffordshire have discovered the first evidence of a link between human exposure to aluminium and multiple sclerosis.

Their research has demonstrated very high (up to 40 times the control level) urinary excretion of aluminium in MS, particularly so in the relapsing-remitting form of the disease. Urinary excretion of iron was also significantly elevated in MS and particularly so in the secondary progressive form of the disease.

Urinary excretion of silicon, the ‘natural' antagonist to the potential toxicity of aluminium, was decreased in MS and particularly so in secondary progressive form of the disease.

The research suggests that individuals with MS have a higher body burden of aluminium and that their urinary excretion of aluminium is linked to changes taking place during the relapsing-remitting stage of the disease.

Dr Christopher Exley, Birchall Centre for Inorganic Chemistry and Materials Science, Lennard-Jones Laboratories, Keele University, Staffordshire, said: “If, as is currently believed, MS is a disorder resulting from the interplay between the environment and susceptibility genes then our observation of elevated excretion of iron may be indicative of the latter, while elevated excretion of aluminium suggests that exposure to aluminium may be the hitherto unrecognised environmental factor in MS.”

Other researchers involved in the study were: Godwin Mamutse(2), Olga Korchazhkina(3), Eleanor Pye(2), Stanislav Strekopytov(1), Anthony Polwart(4), Clive Hawkins(2).

(2) - Department of Neurology, University Hospital of North Staffordshire, Keele University, Staffordshire, UK.

(3) - Institute for Science and Technology in Medicine, Keele University, Staffordshire, UK.

(4) - School of Life Sciences, Huxley Building, Keele University, Staffordshire, UK.

KEELE UNIVERSITY
Keele
Staffordshire
ST5 5BG
UK
http://www.keele.ac.uk
 
 
 
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