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Recent News and Articles on the Keywords: breast cancer + cancer noninvasive + more  Related to the article below (Last Update: 8/5/2008)

Christina Applegate's Breast Cancer: FAQ
WebMD -
Intraductal cancer, also known as DCIS [ductal carcinoma in situ], is stage 0 breast cancer. It's a noninvasive breast cancer. ...
Early cancer detection increases survival
Altoona Mirror, PA - Jul 31, 2008
To check for breast cancer: Have a doctor examine your breasts about every 3 years when you are in your 20s and 30s. Examining your own breasts beginning in ...
New Treatment Strategies Provide More Options for Patients With ...
Journal of American Medical Association (subscription), IL - Jul 22, 2008
An additional 67 770 US women will be diagnosed in 2008 with the earliest, noninvasive form of breast cancer, carcinoma in situ. "Among women who have early ...
Houston Meeting Highlights: Physics and the Future of Medicine
Newswise (press release) - Jul 29, 2008
MORE DETAILS BELOW "...Recent work by team of researchers from MD Anderson Cancer Center, the Mayo Clinic, and Louisiana State University may bring ...
Public research funding is sought for Erie man's cancer treatment ...
Pittsburgh Post Gazette, PA - Jul 30, 2008
Dr. Curley said the noninvasive RF process could be used on any form of cancer for which a targeting molecule can be developed. ...
STFC spin-out company raises 750k funding to improve ...
PublicTechnology.net, UK -
This concept is also being researched for its potential to diagnose breast cancer and detect bone disease non invasively. Dr Darren Andrews, Chief Executive ...
Online support
Malaysia Star, Malaysia - Jul 23, 2008
?I have to see a specialist for something that they suspect is very early breast cancer.? It was my real friends who accompanied me to the medical ...
Bioimpedance Spectroscopy is More Accurate and Reliable Than Other ...
Earthtimes (press release), UK - Jul 21, 2008
In breast cancer patients, this can occur after surgery, such as removal or biopsy of the lymph nodes, and/or radiation therapy. ...
UCLA scientists use PET scans to locate, track prostate cancer ...
CBC.ca, Canada - Jul 11, 2008
This type of approach was pioneered in the field of breast cancer with testing of the sentinel lymph node, the first place breast cancer goes when it ...
Proton therapy debated
DetNews.com, MI - Jul 30, 2008
The center could branch out to treating more common types of cancer such as lung, breast and prostate cancer, Vicini said, but for now, medical evidence is ...
Source: Google News

… for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project … -
B Fisher - J Natl Cancer I, 1998 - jnci.oxfordjournals.org
... events occurred more frequently in women aged 50 years or older. Conclusions: Tamoxifen
decreases the incidence of invasive and noninvasive breast cancer. ...

The effect of raloxifene on risk of breast cancer in postmenopausal women -
SR Cummings, S Eckert, KA Krueger, D Grady, TJ … - feedback, 2005 - biomedcentral.com
... cases of breast cancer (invasive and non-invasive types combined ... risk of ER positive
invasive breast cancer (RR, 0.10 ... in the risk of endometrial cancer was seen ...

… Compared with Lumpectomy and Radiation Therapy for the Treatment of Intraductal Breast Cancer -
B Fisher, J Costantino, C Redmond, E Fisher, R … - New England Journal of Medicine, 1993 - content.nejm.org
... and breast irradiation, ipsilateral breast cancer developed in 28 ... to 7.5 percent
for noninvasive cancers and ... Conclusions Breast irradiation after lumpectomy is ...

Continued Breast Cancer Risk Reduction in Postmenopausal Women Treated with Raloxifene: 4-Year … -
JA Cauley, L Norton, ME Lippman, S Eckert, KA … - Breast Cancer Research and Treatment, 2001 - Springer
... has no apparent effect on non-invasive cancers ... re- duced the incidence of invasive
breast cancer by 49 ... and of invasive estrogen receptor-positive breast can- cer ...

Noninvasive Breast Carcinoma: Results of a National Survey by the American College of Surgeons -
D Rosner, RN Bedwani, J Vana, HW Baker, GP Murphy - Annals of Surgery, 1980 - pubmedcentral.nih.gov
... patients with histologically proven breast cancer surveyed (1.4%). ... rate in patients
with noninvasive carcinoma, treated by more conservative procedures ...

… for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and … -
B Fisher, J Dignam, N Wolmark, E Mamounas, J … - Journal of Clinical Oncology, 1998 - jcojournal.org
... groups; deaths were only infrequently related to breast cancer. Incidence of
noninvasive IBT was reduced from ... lumpectomy plus radiation is more beneficial than ...

… for the Prevention of Breast Cancer: Current Status of the National Surgical Adjuvant Breast and … -
B Fisher, JP Costantino, DL Wickerham, RS Cecchini … - jnci, 2005 - jnci.oxfordjournals.org
... and 5.00%, and 17% had a 5-year risk of more than 5.00 ... 1). Both datasets showed similar
decreases in invasive and noninvasive breast cancer and in osteoporotic ...

Nipple aspirate fluid: a promising non-invasive method to identify cellular markers of breast cancer … -
ER Sauter, E Ross, M Daly, A Klein-Szanto, PF … - Br J Cancer, 1997 - ncbi.nlm.nih.gov
Nipple aspirate fluid: a promising non-invasive method to ... cytology correlated with
increased breast cancer risk (P ... increased as cytology became more abnormal. ...

ABC of breast diseases: Breast cancer?epidemiology, risk factors, and genetics -
K McPherson, CM Steel, JM Dixon - BMJ: British Medical Journal, 2000 - pubmedcentral.nih.gov
... on both invasive and non-invasive breast cancer. Data from the Royal Marsden and
the Italian studies include only the number of invasive cancers. (more ...). ...

The new era in breast cancer. Invasion, size, and nodal involvement dramatically decreasing as a … -
B Cady, MD Stone, JG Schuler, R Thakur, MA Wanner, … - Archives of Surgery, 1996 - Am Med Assoc
... cancer and earlier presentation of noninvasive and invasive ... 1.5 and 1.7 cm, respectively,
for invasive breast cancer. ... hospital); only 10% had more than three ...

Source: Google Scholar
 
 
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Breast Biopsy More Effective In Detecting Cancer Than Noninvasive Diagnostic Tests, Reports ECRI

Article continues below and (thank you)
 
Four common noninvasive diagnostic tests for breast cancer are not accurate enough to rule out breast cancer for women with abnormal findings from mammograms or physical examinations that are suggestive of breast cancer, according to a report from the U.S. Agency for Healthcare Research and Quality (AHRQ) conducted by ECRI, a nonprofit health services research agency. ECRI's evidence report found that the diagnostic tests would miss four to nine percent of breast cancer cases for women with an average risk of the disease as compared to biopsy. The report was reviewed by distinguished breast cancer researchers, including radiologists, prior to publication.

ECRI, an Evidence-based Practice Center, produced the comparative-effectiveness report for AHRQ's new Effective Health Care Program. Publicly available on AHRQ's Web site at effectivehealthcare.ahrq.gov/synthesize/reports/final.cfm, Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities finds that each of the four tests - magnetic resonance imaging (MRI), ultrasonography, positron emission tomography (PET) scanning, and scintimammography-would miss cases of cancer if used alone to evaluate women with abnormal mammograms suggestive of breast cancer.

"So many women today undergo biopsies only to learn they do not have breast cancer. Hopefully, noninvasive tests can continue to improve so that in the future, there will be a viable alternative to biopsy," said AHRQ's director, Carolyn M. Clancy, M.D. "But early and accurate diagnosis of breast cancer is crucial, and at this time, biopsies remain the most effective technique when mammography or physical examination reveals a potential problem."

Mammography and physical examination are both used to detect the possibility of breast cancer. A woman with an abnormal mammogram or physical examination needs further confirmation to determine whether cancer is present. Currently, confirmation is sometimes recommended through a tissue biopsy, either by surgical excision or needle sampling. Only about one in five women currently getting a biopsy for an abnormal mammogram or breast examination has breast cancer. The need for confirmation of the mammogram means some 80 percent of women with an abnormal mammogram who undergo the biopsy procedure ultimately are found not to have cancer. Accurate noninvasive tests could reduce the number of women needing to undergo a biopsy.

A total of 81 studies met ECRI's inclusion criteria for the systematic review. Although all of the technologies evaluated could reduce the need for biopsy in women with abnormal mammogram findings who do not have cancer, each would miss some cancers. The four tests reviewed in the study, and their results, were:

-- Magnetic resonance imaging (MRI) - MRI images are created by the recording of signals generated after radio-frequency excitation of nuclear particles exposed to a strong magnetic field. For every 1,000 women with negative MRI results, about 962 would avoid an unnecessary biopsy but 38 would have missed cancers.

-- Ultrasonography - Ultrasound uses high-frequency sound waves that reflect at boundaries with different acoustic properties (e.g., between fatty breast tissue and a fluid-filled cyst). For every 1,000 women with negative ultrasound test results, about 950 women would avoid an unnecessary biopsy but 50 women would have missed cancers.

-- Positron emission tomography (PET) scanning - In PET scanning, a small amount of radioactive glucose is injected into the bloodstream. A gamma camera scanner, whole body scanner, or specific breast scanner is used for breast imaging to scan for glucose uptake. For every 1,000 women with negative PET scan results, about 924 women would avoid an unnecessary biopsy but 76 women would have missed cancers.

-- Scintimammography - Scintimammography is a nuclear medicine scan using 99mTc-sestamibi (most commonly) as a radioactive tracer injected into the bloodstream. For every 1,000 women with negative scintimammogram results, about 907 women would avoid an unnecessary biopsy but 93 women would have missed cancers.

The findings are calculated based on average risk for cancer and reflect predicted results if the technology were to be used in isolation and as a single examination following an abnormal mammogram suggestive of breast cancer. Risks for individual women may vary widely, based on factors such as age, family history, and specific findings on mammogram or physical examination. The report says that women who may wish to undergo a noninvasive procedure should discuss their individual risk of cancer with their healthcare provider.

ECRI is one of 13 Evidence-based Practice Centers carrying out effectiveness research for AHRQ's new Effective Health Care Program. In addition to performing government-funded work, ECRI delivers health technology assessment information to hospitals, health systems, health plans, and government agencies to its membership through its Health Technology Assessment Information Service™ (HTAIS). HTAIS evaluates technologies along the continuum of evidence from research and development into wide utilization. The program helps organizations make informed decisions about the use of medical devices, drugs, procedures, and healthcare services.

For information about HTAIS, visit
http://www.ecri.org
 
 
 
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