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Recent News and Articles on the Keywords: vanadium + play + role  Related to the article below (Last Update: 8/5/2008)

Steel industry could play bigger role in Asgisa
Creamer Media's Engineering News, South Africa - Jul 10, 2008
The steel industry could play a bigger role in South Africa?s Accelerated and Shared Growth Initiative for South Africa (Asgisa) if government can encourage ...
The other precious metals and where to find them
MoneyWeek (subscription), UK - Jul 17, 2008
And finally, there are no stockpiles of vanadium or substitutes of equal quality. It's tough to find a good pure play that is easy to buy. ...
As fly ash piles up, the challenge for safe disposal rises
The Virginian-Pilot, VA - Jul 26, 2008
"Further, high levels of vanadium were detected in the groundwater recovered from the monitoring wells. It is the opinion of our fly ash expert that ...
Low-Temperature Aging Characteristics of Type 316L Stainless Steel ...
RedOrbit, TX - Jul 24, 2008
From this investigation, the possibility is suggested that minor elements microsegregated in ferrite may play a significant role in accelerating spinodal ...
Eloro Completes Acquisition of Strategic Hydrocarbon (Gas) Land ...
MarketWatch - Jul 16, 2008
Soils were also anomalous in iron, titanium, copper, manganese, vanadium, lead, barium and strontium, all known to be associated with hydrocarbons. ...PINK:ELRRF - CVE:ELO - OTC:CMTX
Multivitamin-Mineral Supplements in the Older Americans Act ...
RedOrbit, TX - Jul 10, 2008
Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, ...
Le vanadium de plus en plus demand?
La Chronique Agora, France - Jul 9, 2008
Enfin, il n'y a pas de stock de vanadium ou de substitut de qualit? ?gale. - Difficile de trouver une valeur pure play facile ? acheter. ...
Source: Google News

Does vanadium play a role in cellular regulation?
T Ramasarma, FL Crane - Curr Top Cell Regul, 1981 - ncbi.nlm.nih.gov
Curr Top Cell Regul. 1981;20:247-301. Does vanadium play a role in cellular
regulation? Ramasarma T, Crane FL. Publication Types ...

The role of vanadium in the management of diabetes -
SM Brichard, JC Henquin - Trends in Pharmacological Sciences, 1995 - Elsevier
... These in vivo studies have established that a direct action of vanadium on the target
tissues of insulin is likely to play a determinant role in the ...

Chemistry, spectroscopy and the role of supported vanadium oxides in heterogeneous catalysis -
BM Weckhuysen, DE Keller - Catalysis Today, 2003 - Elsevier
... Chemistry, spectroscopy and the role of supported vanadium oxides in ... When the vanadium
oxide loading increases two effects come into play: (1) the pH near ...

Vanadium: A Review of its Potential Role in the Fight Against Diabetes -
V Badmaev, S Prakash, M Majeed - The Journal of Alternative and Complementary Medicine, 1999 - liebertonline.com
... have been described and include im- also play an important role in thyroid ... abortions
and perinatal mortality, bone abnor- Interestingly, vanadium levels in ...

A possible role of oxidative stress in the vanadium-induced cytotoxicity in the MC3T3E1 osteoblast … -
AM Cortizo, L Bruzzone, S Molinuevo, SB Etcheverry - Toxicology, 2000 - Elsevier
... characteristics of the cells, as well as their mechanisms of defence and certain
geometric features of the vanadium species, also play a role in vanadium ...

Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest -
Z Zhang, SS Leonard, C Huang, V Vallyathan, V … - Free Radical Biology and Medicine, 2003 - Elsevier
... 9. T. Ramasarma and FL Crane, Does vanadium play a role in cellular
regulation?. Curr. Top. Cell Regul. 20 (1981), pp. 247?301. ...

The Kinetic Significance of V5+ in n-Butane Oxidation Catalyzed by Vanadium Phosphates -
GW Coulston, SR Bare, H Kung, K Birkeland, GK … - Science, 1997 - sciencemag.org
... to polyester resins, is made by oxidation of n-butane over vanadium phosphate catalysts. ...
The results also suggest that V 5+ species may play a role in the ...

Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen species -
L Wang, D Medan, R Mercer, D Overmiller, S … - Journal of Cellular Physiology, 2003 - doi.wiley.com
... and apoptosis, and that macrophages play an important role in the clearance of these
apoptotic cells. Effects of ROS scavengers on vanadium-induced apoptosis ...

Vanadium oxide monolayer catalysts. 3. A Raman spectroscopic and temperature-programmed reduction … -
F Roozeboom, MC Mittelmeijer-Hazeleger, JA Moulijn … - The Journal of Physical Chemistry, 1980 - pubs.acs.org
... Thus crystal size, combined with crystal orientation, may play an important role
in reduction ... T (K) Figure 3. TPR profiles of impregnated vanadium(V) oxidely ...

Vanadate-induced gene expression in mouse C127 cells: roles of oxygen derived active species -
X Yin, AJ Davison, SS Tsang - Molecular and Cellular Biochemistry, 1992 - Springer
... Oxygen-derived active species play a role in tumori- genesis, at least at
the tumor promotion stage [28-30]. ... Vanadium is a pro-oxidant. ...

Source: Google Scholar
 
 
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Vanadium appears to play role in speeding recovery from infections

Article continues below and (thank you)
 
Dietary supplements containing vanadium are used by body builders to help beef up muscles and by some diabetic people to control blood sugar. New research now suggests the naturally occurring but easily toxic element may help prepare the body to recover speedily from infections from gram-negative organisms such as E. coli.

In research at the University of Illinois at Urbana-Champaign, scientists are trying to understand how recovery might be encouraged and why people with diabetes tend to have lingering behavioral symptoms such as fatigue and apathy long after many infections end.

Their latest research found that mice given vanadium -- in its typical vanadyl sulfate form -- before exposure to a pathogen sped recovery in both diabetic and non-diabetic animals. They also tested pre-treatment with insulin-like growth factor (IGF-1), which vanadium mimics, but only the non-diabetic mice recovered quickly after exposure.

The new paper appeared on line Oct. 10 ahead of regular journal publication in the Proceedings of the National Academy of Sciences.

Researchers Daniel R. Johnson, a doctoral student, and Dr. Gregory Freund, head of the pathology department in the College of Medicine at Urbana-Champaign, don't suggest adding vanadium supplements to everyday diets. However, they said, the findings raise questions about just how it works and how it might be useful in speeding recovery.

The amount of vanadium used in the study was comparable to that found in nutritional supplements. While its nutritional value is unclear, the body needs an estimated 10 to 20 micrograms a day and obtains it mostly from plant material. Vanadium in much higher levels becomes toxic. Its use for building muscles has not been confirmed, but vanadium has improved insulin sensitivity and reduced blood sugar in diabetic people.

In their research, Johnson first administered a low dose of lipopolysaccharide (LPS), a molecule present on E. coli and other gram-negative bacteria, to both diabetic and non-diabetic mice after they had been given IGF-1. Non-diabetic mice recovered more quickly than diabetic mice, suggesting, he said, an insulin resistance state in the diabetic animals.

Next, experimental mice were pre-treated with vanadyl sulfate before exposure to LPS. Recovery after illness of the vanadium-treated mice, diabetic or not, was 50 percent faster than that of the untreated control mice.

"With vanadyl sulfate being like IGF-1, we expected to see resistance in the diabetic animals, but we didn't see that," Johnson said. "We saw similar improvement. Thus it must have been acting through a different pathway than do IGF-1 or insulin."

Johnson and Freund, also an adjunct professor of animal sciences and a researcher in the immunophysiology and behavior program at Illinois, theorize it may be vanadium's metal-related shape or its ability to inhibit tyrosine phosphatases, which help to modulate signaling proteins, in the immune system. Freund and colleagues last year documented a connection between serine phosphorylation and anti-inflammatory cytokines.

"Diabetes affects millions of people," Freund said. "It is hard to overcome many of the problems in a nutritionally dependent fashion. This research implies that metals that are trace elements may have more importance than we realize to human health, not only in preventing diseases but also in making you feel better."

It's possible, Johnson said, that taking vanadyl-sulfate-containing supplements beginning two weeks before possible exposure to gram-negative organisms might help speed recovery from subsequent infection.

Co-authors with Freund and Johnson were Jason C. O'Connor, a postdoctoral researcher in animal sciences, and Robert Dantzer, an adjunct professor in the department of animal sciences and professor at the French National Center for Scientific Research.

The National Institutes of Health, American Heart Association and U. of I. Agricultural Experiment Station funded the research.

Jim Barlow, Life Sciences Editor
jebarlow@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
http://www.uiuc.edu
 
 
 
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