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Recent News and Articles on the Keywords: grapefruit + cancerfighting + 805  Related to the article below (Last Update: 8/5/2008)


The Canadian Press
Grapefruit and mint sushi cone refreshing snack with a difference
The Canadian Press - Aug 1, 2008
Sushi is all the rage, so why not try making this refreshing rendition that combines grapefruit, mint and sushi rice in a nori cone. ...

New York Daily News
Top Tokyo chefs use their noodles at Matsugen
New York Daily News, NY - 14 minutes ago
For dessert, there is a deceptive grapefruit jelly. It looks like four simple grapefruit sections, but it tastes like grapefruit fireworks, ...

Albert Lea Tribune
Looking Back: A grapefruit connection with Texas
Albert Lea Tribune, MN - Aug 2, 2008
In 1929 Drs. HD Burns and OA Watland of Albert Lea went to McAllen to purchase land which already had grapefruit trees. Before long they were joined by six ...

Chatham Courier
Wegmans recalls sorbets with milk
Baltimore Sun, United States - Aug 1, 2008
The sorbets -- lemon, raspberry, green apple and pink grapefruit -- were sold in paperboard containers in the ice cream section of Wegmans stores in ...
Wegmans sorbet contains milk not listed on label Allentown Morning Call
Search continues for alleged rapist Centre Daily Times
Wegmans recalls sorbet MPNnow.com
Scranton Times-Tribune
all 34 news articles »
Some Wegmans-brand sorbets recalled
United Press International -
The four recalled sorbet flavors -- Lemon, Raspberry, Green Apple and Pink Grapefruit -- listed "best by" dates ranging from September 2008 to March 2009. ...
Sail through the afternoon and soak up antioxidants with a ...
guardian.co.uk, UK - Jul 27, 2008
Cut the grapefruit in half. Run a sharp knife between the pith and the flesh of each segment, then use a spoon to scoop out the segments into a bowl. ...
Beauty: Summer escape
New Zealand Herald, New Zealand - Aug 2, 2008
A light, invigorating citrus scent, but the range is also available in Rain and Cucumber and, from August 11 for a limited time, in Basil, Grapefruit and ...
Popular ice cream maker issues sorbet recall
WIVB, NY - Aug 1, 2008
The recall includes lemon, raspberry, green apple and pink grapefruit sorbet sold in 16 ounce cartons. Customers can return them to Wegmans for a full ...
Recalls: Wegmans Sorbet, Viapro supplements The Associated Press
News Minute: Here is the latest news from The Associated Press WCAX
Armory in Rochester could be auctioned Rochester Democrat and Chronicle
all 42 news articles »
8 Things You Always Wanted to Know About Dieting
RedOrbit, TX - Aug 2, 2008
Will grapefruit help you burn fat? We debunk the myths and provide the skinny on your most pressing weight-loss questions. YOUR CUBE MATE ADVISES against ...
X Games highlights
San Diego Union Tribune, United States - Aug 2, 2008
My elbow's the size of a grapefruit, both of 'em. And my face feels like I got punched by a 350-pound bouncer a couple times. ...
Source: Google News

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A … -
KS Lown, DG Bailey, RJ Fontana, SK Janardan, CH … - Journal of Clinical Investigation, 1997 - pubmedcentral.nih.gov
... Copyright notice. Grapefruit juice increases felodipine oral availability
in humans by decreasing intestinal CYP3A protein expression. ...

Interaction between grapefruit juice and midazolam in humans. -
HH Kupferschmidt, HR Ha, WH Ziegler, PJ Meier, S … - Clin Pharmacol Ther, 1995 - ncbi.nlm.nih.gov
1995 Jul;58(1):20-8. Interaction between grapefruit juice and midazolam in humans.
Kupferschmidt HH, Ha HR, Ziegler WH, Meier PJ, Kr?henb?hl S. ...

Grapefruit juice?simvastatin interaction: Effect on serum concentrations of simvastatin, … -
JJ Lilja, KT Kivist?, PJ Neuvonen - Clinical Pharmacology & Therapeutics, 1998 - nature.com
... Grapefruit juice?simvastatin interaction: Effect on serum concentrations of
simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors *. ...

Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid -
T Kantola, KT Kivist?, PJ Neuvonen - Clinical Pharmacology & Therapeutics, 1998 - nature.com
Clinical Pharmacology & Therapeutics (1998) 63, 397?402; doi: Grapefruit juice greatly
increases serum concentrations of lovastatin and lovastatin acid *. ...

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice -
MPD PharmD, LH Warbasse, DJE PharmD - Clinical Pharmacology & Therapeutics, 1995 - nature.com
Clinical Pharmacology & Therapeutics (1995) 57, 485?491; doi: Disposition of
intravenous and oral cyclosporine after administration with grapefruit juice *. ...

Drug interactions with grapefruit juice. -
B Ameer, RA Weintraub - Clin Pharmacokinet, 1997 - ncbi.nlm.nih.gov
Clin Pharmacokinet. 1997 Aug;33(2):103-21. Drug interactions with grapefruit juice.
Ameer B, Weintraub RA. Princeton Junction, New Jersey, USA. ...

Grapefruit juice-drug interactions -
DG Bailey, J Malcolm, O Arnold, J David Spence - Br J Clin Pharmacol, 1998 - Blackwell Synergy
... Free Content. Full Text. Grapefruit juice?drug interactions. David ... content. Drugs
interacting with grapefruit juice. Summary of studied drugs. ...

… of Enhanced Oral Availability of CYP3A4 Substrates by Grapefruit Constituents. Decreased enterocyte … -
P Schmiedlin-Ren, DJ Edwards, ME Fitzsimmons, K He … - Drug Metabolism and Disposition, 1997 - ASPET
... ACCELERATED COMMUNICATION Mechanisms of Enhanced Oral Availability of CYP3A4 Substrates
by Grapefruit Constituents Decreased enterocyte CYP3A4 concentration ...

Grapefruit-felodipine interaction: Effect of unprocessed fruit and probable active ingredients -
DGB PhD, GK Dresser, JH Kreeft, C Munoz, DJF PhD, … - Clinical Pharmacology & Therapeutics, 2000 - nature.com
... 10.1067/mcp.2000.110774. Grapefruit-felodipine interaction: Effect of
unprocessed fruit and probable active ingredients *. David G ...

Identification of 6', 7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice. -
DJ Edwards, FH Bellevue 3rd, PM Woster - Drug Metab Dispos, 1996 - ncbi.nlm.nih.gov
Drug Metab Dispos. 1996 Dec;24(12):1287-90. Click here to read Identification of
6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice. ...

Source: Google Scholar
 
 

Grapefruit juice may contain cancer-fighting compounds

Citrus fruits like oranges and grapefruits are known to be a rich source of vitamin C but new evidence suggests they also contain compounds that fight cancer.
 
Researchers at Texas A&M University reported this week that freeze-dried grapefruit pulp, similar to whole grapefruit, reduced the incidence of early colon cancer lesions in an animal model of the disease.

Meanwhile a researcher at Kanazawa Medical University in Japan showed that nobiletin, a compound found in tangerines, has also demonstrated possible action against colon cancer.

Cancer of the colon or rectum is the second deadliest form of cancer after lung cancer but is also considered one of the most preventable types of cancer, as there are several dietary factors that appear to play a protective role against the disease.

In another trial, presented yesterday at the symposium on health benefits of citrus fruits, taking place during the American Chemical Society's national meeting this week, a team from the University of Hawaii reported that drinking grapefruit juice may help reduce the risk of cancer in smokers.

In a controlled study involving 49 smokers, the researchers found that those drinking three 6-ounce glasses of grapefruit juice a day reduced the activity of a liver enzyme called CYP1A2 that is thought to activate cancer-causing chemicals found in tobacco smoke.

The meeting underlines the nutraceutical potential of the fruit at a time when sales are being hit by the current trend for low-carb diets as well as warnings about the interaction between grapefruit and prescription drugs.

Grapefruit are a key component of the once fashionable ‘grapefruit diet', now pushed to the sidelines by the low-carb mania. But a recent trial, reported earlier this year and presented at the meeting yesterday, suggests that grapefruit may indeed stop weight gain by lowering insulin levels.

Meanwhile the fruit's effects on drugs could be turned into a benefit for the pharmaceutical industry. Scientists at Texas A&M Citrus Center have identified three compounds belonging to a class called furocoumarins that are responsible for inhibiting a key enzyme, CYP3A4, that metabolizes and regulates certain drugs involved in the grapefruit-drug interaction.

The researchers hope that these enzyme-blockers can eventually be developed into a ‘super-pill' or specialty grapefruit juice that can be co-administered with prescription drugs to increase their bioavailability, thus reducing dose and cost.

Roughly two-thirds of the world's grapefruit and grapefruit juice hail from Florida.

 
 
 
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