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Recent News and Articles on the Keywords: colorectal cancer + selenium + risk  Related to the article below (Last Update: 8/5/2008)

It's easy to add healthy, unrefined food to your diet
Sarasota Herald-Tribune, FL -
They reduce the risk of stroke, type 2 diabetes, heart disease, asthma, colorectal cancer, high blood pressure, gum disease and tooth loss. ...
Raw Broccoli, Cabbage Slash Bladder Cancer Risk by 40 Percent ...
Natural News.com, AZ - Jul 18, 2008
In other words, healthy pee keeps you cancer-free! Healthy poo, by the way, stops colorectal cancer, which is yet another reason to stop eating milk, ...
Source: Google News

A Prospective Cohort Study on Toenail Selenium Levels and Risk of Gastrointestinal Cancer -
PA Brandt, RA Goldbohm, P van't Veer, P Bode, E … - jnci, 1993 - jnci.oxfordjournals.org
... CB Foster, A. Schatzkin, and RB Hayes High serum selenium and reduced risk of advanced
colorectal adenoma in a colorectal cancer early detection program. ...

Baseline Characteristics and the Effect of Selenium Supplementation on Cancer Incidence in a … -
AJ Duffield-Lillico, ME Reid, BW Turnbull, GF … - Cancer Epidemiology Biomarkers & Prevention, 2002 - AACR
... A. Schatzkin, and RB Hayes High Serum Selenium and Reduced Risk of Advanced Colorectal
Adenoma in a Colorectal Cancer Early Detection Program Cancer Epidemiol. ...

Reduced risk of colon cancer with high intake of vitamin E: the Iowa Women's Health Study -
RM Bostick - Cancer Research, 1993 - AACR
... A and C and beta-carotene, and among users of selenium supplements, were not ... a high
intake of vitamin E may decrease the risk of colon cancer, especially in ...

Risk of cancer in relation to serum concentrations of selenium and vitamins A and E: matched case- … -
JT Salonen, R Salonen, R Lappetel?inen, PH … - British Medical Journal (Clinical research ed.), 1985 - pubmedcentral.nih.gov
... 1981;2(6):519?522. [PubMed]; Birt DF, Lawson TA, Julius AD, Runice CE, Salmasi S.
Inhibition by dietary selenium of colon cancer induced in the ... Cancer Res. ...

Meat Consumption and Risk of Colorectal Cancer -
A Chao, MJ Thun, CJ Connell, ML McCullough, EJ … - JAMA, 2005 - Am Med Assoc
... against colon cancer. Poultry contains small amounts of nutrients such as selenium
and calcium that have been associated with lower risk of colorectal neoplasia ...

The Selenium and Vitamin E Cancer Prevention Trial -
EA Klein, SM Lippman, IM Thompson, PJ Goodman, D … - World Journal of Urology, 2003 - Springer
... activity and other factors for colorectal cancer: a prospective ... and A and risk of
lung cancer: the NHANES ... et al (1998) Study of prediagnostic selenium level in ...

… incidence of prostate cancer with selenium supplementation: results of a double-blind cancer … -
F Password - Br J Urol, 1998 - Blackwell Synergy
... cases were diagnosed in the selenium-treated group ... other secondary endpoints of total
cancer mortality, and the incidence of total, lung and colorectal cancer. ...

ASSOCIATION BETWEEN SERUM SELENIUM AND THE RISK OF CANCER -
JT SALONEN, G ALFTHAN, JK HUTTUNEN, P PUSKA - American Journal of Epidemiology, 1984 - Oxford Univ Press
... Predi- agnostic serum selenium and risk of cancer. ... Biochemical and clinical effects
of selenium on dimethylhy- drazine-induced colon cancer in rats. ...

… Retinol, Beta-Carotene, Vitamin E, and Selenium As Related to Subsequent Cancer of Specific Sites -
GW Comstock, TL Bush, K Helzlsouer - American Journal of Epidemiology, 1992 - Oxford Univ Press
... Serum beta-carotene, vitamins A and E, selenium, and the risk of lung ... Serologic
precursors of cancer. I. Prediagnostic se- rum nutrients and colon cancer risk. ...

Serum vitamin E, serum selenium and the risk of gastrointestinal cancer. -
P Knekt, A Aromaa, J Maatela, G Alfthan, RK Aaran, … - Int J Cancer, 1988 - ncbi.nlm.nih.gov
... quintiles. Serum levels of selenium or alpha-tocopherol in general were
not inversely associated with colorectal cancer risk. These ...

Source: Google Scholar
 
 

Higher selenium intake may reduce colorectal cancer risk

Higher blood levels of the trace mineral selenium are associated with lower rates of colorectal neoplasia, finds a new study, suggesting that raising dietary intake of the mineral could protect against colorectal cancer.
 
Selenium has previously been associated with cancer protection, with several studies showing that it may help combat prostate cancer. However past research on selenium and colorectal cancer has yielded mixed results.

Researchers from the University of Arizona say however that these studies may have been too small to track the mineral's impact.

To gain better insight into the selenium's anti-cancer role, they pooled data from three completed clinical trials of colorectal adenoma: the Wheat Bran Fiber Trial, the Polyp Prevention Trial, and the Polyp Prevention Study, each with several hundred participants.

After adjustment for age, gender, smoking status and study site, each of the trials showed lower risk of adenoma recurrence in patients with the highest quartile of blood selenium level versus those in the lowest quartile, although only the Polyp Prevention Study was statistically significant.

Writing in the 17 November issue of the Journal of the National Cancer Institute (96:1645-1647), the authors explain that there are several possible mechanisms for this effect, including protection against DNA damage, induction of apoptosis, and increased immune system activity.

The Selenium and Vitamin E Cancer Prevention Trial (SELECT), looking at the impact of these nutrients on prostate cancer, may provide some new insight into the mechanisms of the mineral's anti-cancer activity.

 
 
 
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