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Recent News and Articles on the Keywords: antidepressants + bleeding + linked  Related to the article below (Last Update: 8/5/2008)

Popular Antidepressants Linked to GI Bleeding
Washington Post, United States - Jul 7, 2008
By Amanda Gardner MONDAY, July 7 (HealthDay News) -- The widely prescribed class of antidepressants known as SSRIs may be associated with bleeding in the ...
Prozac, antidepressants linked in study to stomach bleeding Newsday
Antidepressants Linked to Stomach Bleeding Newsinferno.com
Antidepressants Linked to Gastrointestinal Bleeding | InjuryBoard ... InjuryBoard.com
ABC News - Science Daily (press release)
all 36 news articles »

HealthNews
Antidepressants Linked to Stomach Bleeding
HealthNews, CA - Jul 10, 2008
If you are one of the millions of people taking antidepressants to help control or reduce depression, be aware that these drugs may cause gastrointestinal ...
SSRIs and Venlafaxine Linked to Greater Risk for Gastrointestinal ...
Medscape (subscription) - Jul 14, 2008
The present nested, case-control study aimed to clarify the risk for upper GI tract bleeding from antidepressants. The researchers used data from the Health ...
A link between antidepressants and internal bleeding?
Philadelphia Inquirer, PA - Jul 11, 2008
By John Sullivan Patients taking a popular type of antidepressant are at greater risk for upper gastrointestinal bleeding, according to a new study which ...
PEOPLE'S PHARMACY Beware unexpected drug side effects
Houston Chronicle, United States - Jul 26, 2008
New research suggests, though, that these SSRI antidepressants also increase the risk for bleeding ulcers (Archives of General Psychiatry, July 2008). ...
Grassley, Dingell Lead Calls
Wall Street Journal - Jul 29, 2008
"We gotta stop the bleeding." Controversies over the popular prescription drugs Chantix, an antismoking pill, and cholesterol treatment Vytorin have added ...
Venlafaxine Joins SSRIs in Risk for Upper GI Bleeding
MedPage Today, NJ - Jul 7, 2008
Several earlier studies had linked the serotonin reuptake inhibitors to gastrointestinal bleeding, but only a few case reports had implicated venlafaxine, ...

Insider Medicine
SSRIs May Cause Bleeding, Childhood Nutrition and Intelligence ...
Insider Medicine, Canada - Jul 7, 2008
... a commonly-prescribed class of antidepressants, may be associated with upper GI bleeds. Over 1300 patients with upper GI bleeding were compared to 10000 ...
Antidepressants linked to GI bleeding, study finds
SmartBrief, DC - Jul 16, 2008
A new study found the commonly prescribed antidepressant class SSRIs may cause bleeding in the upper gastrointestinal tract, especially when combined with ...
AMAZING OMEGA-3s
RedOrbit, TX - Jul 13, 2008
The studies have shown omega-3s are beneficial both as a stand-alone and additive treatment to mood stabilizers or antidepressants that people are on. ...
Source: Google News

… of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: … -
C van Walraven, MM Mamdani, PS Wells, JI Williams - BMJ: British Medical Journal, 2001 - pubmedcentral.nih.gov
... The databases are anonymous and linked by unique ... 1, Table 1 Rates of gastrointestinal
bleeding per 1000 person years of observation in antidepressant groups by ...

… Serotonin Reuptake Inhibitors and Risk of Upper Gastrointestinal Tract Bleeding A Population-Based … -
SO Dalton, C Johansen, L Mellemkjaer, HT Sorensen, … - Archives of Internal Medicine, 2003 - Am Med Assoc
... The remaining 29160 persons were linked to the ... condition predisposing to GI bleeding
(alcoholism, esophageal ... of the first notified antidepressant prescription. ...

… selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case- … -
FJ de Abajo, LAG Rodr?guez, D Montero - BMJ: British Medical Journal, 1999 - pubmedcentral.nih.gov
... reuptake inhibitors is similarsuggesting a class effect linked to their ... Antidepressants
associated with upper gastrointestinal bleeding. With the ...

… of Risk of Abnormal Bleeding With Degree of Serotonin Reuptake Inhibition by Antidepressants -
WEE Meijer, ER Heerdink, WA Nolen, RMC Herings, … - Archives of Internal Medicine, 2004 - Am Med Assoc
... Prescription data were linked to hospital discharge data. ... up ended when a gap in
antidepressant prescriptions of ... with a diagnosis related to bleeding as reason ...

… there an association between selective serotonin reuptake inhibitors and risk of abnormal bleeding? -
D Layton, DWJ Clark, GL Pearce, SAW Shakir - European Journal of Clinical Pharmacology, 2001 - Springer
... To investigate whether an associa- tion between the use of selective serotonin reuptake
inhibitor (SSRI) antidepressants and abnormal bleeding is demonstrated ...

Antidepressant drugs: a potential new drug cause of upper gastrointestinal bleeding -
FJ de Abajo, A Garc?a Rodr?guez, D Montero - Digestive and Liver Disease, 2000 - Elsevier
... de- pression episodes may be linked to peptic ... the risk of upper gastrointestinal
bleeding associated with ... Spain, SSRIs are the most widely used antidepressants ...

Selective Serotonin Reuptake Inhibitors and Increased Bleeding Risk: Are We Missing Something? -
VL Serebruany - The American Journal of Medicine, 2006 - Elsevier
... Another elegant study linked the bleeding risks with the degree of serotonin reuptake
inhibition by antidepressants, 9 suggesting a direct link between ...

Selective serotonin re-uptake inhibitors and the risk of bleeding -
RM Weinrieb, M Auriacombe, KG Lynch, JD Lewis - eds, 2005 - Expert Opinion
... study compared hospitalisations for upper GI bleeding in 26,005 ... to those who never
received antidepressants in Denmark [9 ... This information was linked to a compre ...

[CITATION] Serotonin antidepressants linked to bleeding problems in orthopaedic patients
L Barclay, D Lie - Medscape Medical News, 2003

Depression, Alterations in Platelet Function, and Ischemic Heart Disease -
EC Bruce, DL Musselman - Psychosomatic Medicine, 2005 - Am Psychosomatic Soc
... Influence of serotonin-transporter-linked promoter region ... of serotonin reuptake by
antidepressants and upper gastrointestinal bleeding in elderly patients ...

Source: Google Scholar
 
 

SSRI antidepressants linked to increased GI bleeding

 
 
Use of SSRI antidepressants may increase gastrointestinal ( GI ) bleeding.
A study suggests that the increase is similar to that seen with the use of non-steroidal anti-inflammatory drugs ( NSAIDs,).

Previous research showed that use of SSRIs ( selective serotonin reuptake inhibitor ) may be related to an increased risk of bleeding disorders and hemorrhages.

Researchers from Northwestern University examined the use of these and other drugs with similar risks in patients admitted to several hospitals with acute gastrointestinal bleeding.

They found that ongoing SSRI use was associated with a risk of GI bleeding similar to that found in regular NSAID use ( 1.5-fold versus 1.4-fold increase, respectively ).

In the retrospective study, researchers reviewed the records of hospital inpatients admitted with acute GI bleeding between June and December 2003 ( 549 patients ) and compared them to similar patients admitted at the same time period with a non-bleeding diagnosis ( 939 patients ). Patients were excluded if they had a history of liver disease, hypertension, primary hematologic or coagulation disorders.

In a further analysis of the relationship, researchers tracked the combined use of SSRIs, NSAIDs, Aspirin, Plavix, Coumadin and Lovenox ( blood thinning medications used to prevent heart attacks and strokes ).

Researchers found that patients admitted with bleeding were significantly more likely to be using more than one medication associated with an increased risk of GI bleeding than control patients.

" While more research needs to be conducted to examine the link between SSRIs and gastrointestinal bleeding, physicians must closely monitor for this serious adverse event, especially in patients who are currently taking both SSRIs and NSAIDs, " said Michael Jones, lead author from Northwestern University Medical School. " This is a potent example of the need for doctors to be particularly conscientious about potential side effects when prescribing multiple medications for their patients. "

Source: Digestive Disease Week ( DDW ), 2005
 
 
 
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