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Recent News and Articles on the Keywords: women + estrogen + postmenopausal  Related to the article below (Last Update: 8/5/2008)

Chronic Exposure To Estrogen Impairs Some Cognitive Functions
Science Daily (press release) - Aug 1, 2008
A recent large-scale study of HRT in post-menopausal women was stopped because of an increased risk of stroke and blood clots in women taking estrogen alone ...
Genetics, lifestyle affect bone density
Daytona Beach News-Journal, FL - Aug 3, 2008
Because estrogen plays an important role in keeping bone absorption under control, post-menopausal women are more prone to suffer rapid bone loss as ...
Testosterone Predominance Increases Prevalence Of Metabolic ...
Science Daily (press release) - Jul 30, 2008
It was previously thought that estrogen exerted a direct positive effect on cardiovascular disease risk in women, a benefit that was lost as women ...
Jump in CV Risk With Menopause Tied to Hormonally Mediated ... Medscape (subscription)
all 18 news articles »

TopNews
Hip Bone May Hold Breast Cancer Clue
WebMD - Jul 28, 2008
1 edition of Cancer, links higher hip bone density to increased breast cancer risk in postmenopausal women. Higher hip bone mineral density may be a ...
Bone Density Predicts Chances of Breast Cancer Washington Post
Bone Density of Hip Connected to Breast Cancer Risk After Menopause MedPage Today
Study Finds Causal Relationship Between High Bone Density and ... eFluxMedia
all 54 news articles »
Improved Estrogen Reception May Sharpen Fuzzy Memory
Science Daily (press release) - Jul 29, 2008
In addition, previous studies have shown estrogen replacement may improve cognition in postmenopausal women and younger women with low estrogen levels. ...
Soy - Not So Fast
What Doctors Don't Tell You, UK -
They may diminish hot flashes in post-menopausal women; on the other hand, when taken by pregnant women, genisteins may adversely affect the reproductive ...
Urinary tract, yeast infections are a vicious cycle
Burlington Times News, NC -
Because of the structure of their anatomies, women - particularly those who are sexually active and/or post-menopausal - are more prone to infection than ...
CorrespondenceExperiences of a long-term randomized controlled ...
7thSpace Interactive (press release), NY - Aug 1, 2008
Results: After EPHT recruited in 1999-2001 the Women's Health Initiative (WHI) in the USA decided to stop the estrogen-progestin trial after a mean of 5.2 ...
Low-Fat Diet May Not Protect Postmenopausal Women From Diabetes Risk
Medscape (subscription) - Jul 30, 2008
Report whether a low-fat diet affects the incidence of diabetes mellitus in postmenopausal women. Describe the role of weight loss in the effect of a ...
Myths About Postmenopausal Pain During Sex Shattered
Science Daily (press release) - Jul 15, 2008
ScienceDaily (July 14, 2008) ? Using hormone replacement therapy to alleviate painful sexual intercourse in post-menopausal women is not effective for a ...
Source: Google News

… of Estrogen Plus Progestin in Healthy Postmenopausal Women. Principal Results From the Women's … -
JE Rossouw, GL Anderson, RL Prentice, AZ LaCroix, … - Journal of the American Medical Association, 2002 - escholarship.umassmed.edu
... Risks and benefits of estrogen plus progestin in healthy postmenopausal women:
principal results From the Women's Health Initiative randomized controlled trial. ...

… Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women -
S Hulley, D Grady, T Bush, C Furberg, D Herrington … - JAMA, 1998 - Am Med Assoc
... MANY OBSERVATIONAL studies have found lower rates of coronary heart disease (CHD)
in women who take postmenopausal estrogen than in women not receiving this ...

Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health … -
GL Anderson, M Limacher, AR Assaf, T Bassford, SA … - JAMA, 2004 - Mass Med Soc
... Anderson GL et al. Effects of conjugated equine estrogen in postmenopausal women
with hysterectomy: The Women's Health Initiative randomized controlled trial. ...

The Effect of Postmenopausal Estrogen Therapy on Bone Density in Elderly Women -
DT Felson, Y Zhang, MT Hannan, DP Kiel, P Wilson, … - New England Journal of Medicine, 1993 - content.nejm.org
... Fam Pract 16: 335-342 [Abstract] [Full Text]; Pinkerton, JV, Santen, R. (1999).
Alternatives to the Use of Estrogen in Postmenopausal Women. Endocr. Rev. ...

… acutely attenuates abnormal coronary vasomotor responses to acetylcholine in postmenopausal women -
SE Reis, ST Gloth, RS Blumenthal, JR Resar, HA … - Circulation, 1994 - Am Heart Assoc
... These acute effects of estrogen on coronary vasoreactivity may explain, in part,
the cardioprotective effects of estrogen in postmenopausal women. ...

Hormone therapy to prevent disease and prolong life in postmenopausal women. -
D Grady, SM Rubin, DB Petitti, CS Fox, D Black, B … - Ann Intern Med, 1992 - ncbi.nlm.nih.gov
... the risks and benefits of hormone therapy for asymptomatic postmenopausal women
who are ... language literature since 1970 on the effect of estrogen therapy and ...

Acute vascular effects of estrogen in postmenopausal women -
DM Gilligan, DM Badar, JA Panza, AA Quyyumi, RO … - Circulation, 1994 - Am Heart Assoc
... endothelium-independent vasodilation in post-menopausal women with risk ... term benefit
of estrogen therapy on cardiovascular events in postmenopausal women. ...

Postmenopausal Estrogen and Progestin Use and the Risk of Cardiovascular Disease. -
F Grodstein, MJ Stampfer, JAE Manson, GA Colditz, … - Obstetrical & Gynecological Survey, 1997 - obgynsurvey.com
... also indicated that there was little difference in the magnitude of reduction of
coronary artery disease in postmenopausal women between estrogen alone and ...

Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women -
DM Gilligan, AA Quyyumi, RO Cannon - Circulation, 1994 - Am Heart Assoc
... Association. ARTICLES. Effects of physiological levels of estrogen on coronary
vasomotor function in postmenopausal women. DM Gilligan ...

… Dementia and Mild Cognitive Impairment in Postmenopausal Women The Women's Health Initiative Memory … -
SA Shumaker, C Legault, SR Rapp, L Thal, RB … - JAMA, 2003 - Am Med Assoc
... sectional, 17 and prospective studies 11, 18-22 have reported a lower risk of dementia
for women taking compared with those not taking postmenopausal estrogen. ...

Source: Google Scholar
 
 

Postmenopausal women who have undergone hysterectomy should not take Estrogen

 
 
The U.S. Preventive Services Task Force issued a new recommendation against the routine use of Estrogen to prevent chronic conditions such as heart disease, stroke and osteoporosis in postmenopausal women who have undergone a hysterectomy.
This recommendation is based on recent evidence from the National Institutes of Health’s Women’s Health Initiative clinical trial and other studies.

In 2002, the Task Force found insufficient evidence to recommend for or against the routine use of Estrogen alone to prevent chronic conditions in women who have completed menopause and had a hysterectomy.

Now, after reviewing new findings from the Women’s Health Initiative, the Task Force noted that, although Estrogen can have positive effects such as reducing the risk for fractures, hormone therapy should not be used routinely because it appears to increase women’s risk for potentially life-threatening clots that block blood vessels ( venous thromboembolism ), stroke, dementia and mild cognitive impairment.

The Task Force noted that while the use of Estrogen reduces the risk for fracture, drugs such as bisphosphonates and calcitonin are available and effective in helping prevent fractures in women diagnosed with osteoporosis.

The Task Force concluded that for most women, the harmful effects of Estrogen therapy outweigh any benefits for fracture and other chronic conditions.

In addition, the Task Force reaffirmed its earlier recommendation against the routine use of combined Estrogen and Progestin for preventing chronic conditions in postmenopausal women. Although the combination therapy may reduce risk for fractures in women diagnosed with osteoporosis and for colorectal cancer, it has no beneficial effect on heart disease and may even put women at greater risk for the condition.

Other potential harms of combined Estrogen and Progestin include increased risk for breast cancer, venous thromboembolism, inflammation of the gallbladder, dementia and mild cognitive impairment.

The Task Force concluded that the harmful effects of combined Estrogen and Progestin are likely to exceed the chronic disease prevention benefits for most women.

The Task Force did not examine the effects of Estrogen only or combined Estrogen and Progestin for the treatment of menopausal symptoms, only for the prevention of chronic disease.
Menopause occurs in most women in the United States between 41 to 59 years of age, although the body’s production of Estrogen and Progestin may begin to decrease years before.
The average woman going through menopause has a 46 percent likelihood of developing heart disease over her lifetime, a 20 percent likelihood of stroke, a 15 percent likelihood of bone fracture, and a 10 percent chance of developing breast cancer.

Source: AHRQ, 2005
 
 
 
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