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Recent News and Articles on the Keywords: benign + disease + prostate  Related to the article below (Last Update: 8/4/2008)

Panel advises men over 75 to avoid prostate cancer screening
Contra Costa Times, CA -
"We know that prostate cancer is a slow-growing disease and years ago used to say that 70 might be the cutoff. Now that the population is aging and ...
NIDDK publishes a strategic plan for research into benign prostate ...
Medicexchange, UK - Jul 29, 2008
The research area of benign prostate disease includes two of the most significant non-cancerous disorders affecting males - benign prostatic hyperplasia ...
Might science soon help stave off the decay of old age?
Globe and Mail, Canada - Aug 1, 2008
But as men get older, testosterone can cause the prostate gland to swell and make it harder for them to empty their bladders. They produce a weak, ...
Early screening vital for men
New Straits Times, Malaysia - Jul 28, 2008
It will educate men on the importance of screening as well as seek to detect new cases of prostate cancer, especially the early stage of the disease, benign ...
What You Should Know Before You Spit Into That Test Tube
Washington Post, United States - Jul 21, 2008
By Rick Weiss Jeffrey Gulcher had no reason to think much about prostate cancer. He was just 48, and the disease typically strikes later in life. ...
Cutting-Edge Care
RedOrbit, TX -
TomoTherapy treatments are painless and are most often used for prostate, head and neck, central nervous system and cranial tumors. "It's unlike any other," ...
Localized prostate cancer rarely helped by hormone therapy
Los Angeles Times, CA - Jul 9, 2008
Hormonal therapy, which sounds rather benign, "has become the second-most popular treatment after surgery, surpassing radiation," he said. ...
Prostate problems - don't suffer in silence
Spenborough Guardian, UK - Jul 25, 2008
By Margaret Heward MEN who worry they may be suffering from prostate disease must not suffer in silence, says a Liversedge-based continence adviser. ...
Dendreon Expects Interim Data Analysis for Phase 3 PROVENGE IMPACT ...
FOXBusiness - Jul 23, 2008
PROVENGE is the Company's investigational active cellular immunotherapy for the treatment of advanced prostate cancer. Should the pre-specified criterion ...DNDN - OTC:CMTX

iAfrica.com
Facts of breast cancer
iAfrica.com, South Africa - Jul 29, 2008
This means that if a biopsy of a breast lump shows certain types of benign breast disease, this may indicate a slightly increased risk of breast cancer. ...
Source: Google News

… of Free Prostate-Specific Antigen to Enhance Differentiation of Prostate Cancer From Benign … -
WJ Catalona, AW Partin, KM Slawin, MK Brawer, RC … - The Journal of Urology, 1999 - jurology.com
... Use of the Percentage of Free Prostate-Specific Antigen to Enhance Differentiation
of Prostate Cancer From Benign Prostatic Disease: A Prospective Multicenter ...

DISCRIMINATION OF MEN WITH PROSTATE CANCER FROM THOSE WITH BENIGN DISEASE BY MEASUREMENTS OF HUMAN … -
C BECKER, T PIIRONEN, KIM PETTERSSON, T BJ?RK, KJ … - The Journal of Urology, 2000 - Elsevier
... Discrimination of patients with benign prostate disease from those with prostate
cancer was significantly enhanced using measurements of hK2 in addition to ...

… -matching Algorithm Distinguishes Prostate Cancer from Benign Prostate Hyperplasia and Healthy Men 1 -
BL Adam, Y Qu, JW Davis, MD Ward, MA Clements, LH … - Cancer Research, 2002 - AACR
... Quantitation of serum prostate-specific membrane antigen by a novel protein biochip
immunoassay discriminates benign from malignant prostate disease. ...

… specific antigen density: a means of distinguishing benign prostatic hypertrophy and prostate … -
MC Benson, IS Whang, A Pantuck, K Ring, SA Kaplan, … - J Urol, 1992 - ncbi.nlm.nih.gov
... resonance imaging determinations of benign prostatic hypertrophy ... of 61 patients with
prostatic disease clinically confined to the prostate glands (41 ...

Discrimination of Prostate Cancer from Benign Disease by Plasma Measurement of Intact, Free Prostate … -
P Nurmikko, K Pettersson, T Piironen, J Hugosson, … - Clinical Chemistry, 2001 - Am Assoc Clin Chem
... LS Marks, LS Millar, CL Knott, HG Rittenhouse, and SD Mikolajczyk Benign
Prostate-specific Antigen (BPSA) in Serum Is Increased in Benign Prostate Disease ...

… Antigen by a Novel Protein Biochip Immunoassay Discriminates Benign from Malignant Prostate Disease … -
Z Xiao, BL Adam, LH Cazares, MA Clements, JW Davis … - Cancer Research, 2001 - AACR
... Quantitation of Serum Prostate-specific Membrane Antigen by a Novel Protein Biochip
Immunoassay Discriminates Benign from Malignant Prostate Disease 1. ...

… complex between prostate-specific antigen and alpha 1-antichymotrypsin is the major form of prostate … -
UH Stenman - Cancer Research, 1991 - AACR
... LS Marks, LS Millar, CL Knott, HG Rittenhouse, and SD Mikolajczyk Benign
Prostate-specific Antigen (BPSA) in Serum Is Increased in Benign Prostate Disease ...

Serum Proteomic Patterns for Detection of Prostate Cancer -
EF Petricoin, DK Ornstein, CP Paweletz, A Ardekani … - jnci, 2002 - jnci.oxfordjournals.org
... Quantitation of serum prostate-specific membrane antigen by a novel protein biochip
immunoassay discriminates benign from malignant prostate disease. ...

Etiology and disease process of benign prostatic hyperplasia.
JT Isaacs, DS Coffey - Prostate Suppl, 1989 - ncbi.nlm.nih.gov
Prostate Suppl. 1989;2:33-50. Etiology and disease process of benign prostatic
hyperplasia. Isaacs JT, Coffey DS. Oncology Center ...

[CITATION] … clinical trial evaluation of free PSA in the differentiation of prostate cancer from benign disease
WJ Catalona, AW Partin, KM Slawin, MK Brawer, A … - J Urol, 1997

Source: Google Scholar
 
 

Kidney disease linked to benign prostate obstruction

 
 
A Mayo Clinic study found men who experience signs and symptoms of a prostate obstruction resulting from benign prostatic hyperplasia ( BPH ) are three times more likely than other men to develop chronic kidney disease.

" This is the first study on the topic to sample the general community," says Andrew Rule, at the Mayo Clinic, who conducted the study with Steven Jacobsen.

"Symptomatic and non-symptomatic men were compared, unlike clinical trials and studies in a urology practice, which tend to represent only symptomatic men."

BPH and chronic kidney disease pose significant health problems in older men.
Chronic kidney disease ( CKD ) occurs when the kidneys cannot rid metabolic wastes from the body or maintain the proper fluid and chemical balances.
Eventually, the waste builds up and becomes poisonous to the body.
Kidney disease can develop rapidly -- in two to three months -- or gradually over decades.

Many risks coincide with the development of CKD.

" Several studies show men with chronic kidney disease have increased chance of death, hospitalization and cardiovascular events," says Rule.

" Growth of the prostate gland can lead to a bladder outlet obstruction," says Rule. "An obstruction of the bladder can cause inability to or discomfort in emptying the bladder, a slowed stream of urine, frequent urges to void during the night or an enlarged, damaged bladder."

"We were surprised at how much kidney disease can be attributed to BPH," says Jacobsen.

"An obstruction on the urethra is like a dam on a river -- men can still void, but the constant buildup and pressure will ultimately cause damage."

BPH affects about half of men in their 60s and up to 90 percent of men in their 70s and 80s. It is not related to the development of prostate cancer, although causes of BPH tissue growth inside the prostate later in life is unclear. Researchers believe that with age the prostate becomes more susceptible to the effects of hormones, including testosterone.

The most effective way to treat CKD is to care for and manage the underlying disease.

" It has been shown that many patients with kidney disease respond to surgical treatments of BPH," says Rule. "There are also medications to relieve obstructions, by either shrinking the prostate gland or relaxing muscles that contribute to the obstruction."

The recent study surveyed 476 white men, ages 40-79, randomly selected from Olmsted County.

The researchers would like to see if similar findings are reproduced among general populations studied at other research centers.

Jacobsen also suggests further research and testing to determine if treating BPH reverses the progression of kidney disease.

The researchers hope the results of the study will encourage both physicians and patients to consider BPH as a factor in kidney disease.

Source: Mayo Clinic, 2005
 
 
 
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