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Recent News and Articles on the Keywords: cancer + 1,330,000 + web  Related to the article below (Last Update: 8/5/2008)


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Female hormones may affect risk of stomach cancer

Last Updated: 2007-12-20 17:06:17 -0400 (Reuters Health)

By Will Boggs, MD

NEW YORK (Reuters Health) - Women who have been fertile for a higher than average number of years, which occurs when menstruation begins early and menopause begins late, seem to be protected to some degree against developing stomach, or "gastric" cancer, according to a report in the journal Gut.

"Hormonal factors may affect gastric cancer risk," Dr. Neal D. Freedman told Reuters Health, "but future studies are required to determine whether or not this is the case."

Freedman from the National Cancer Institute, Rockville, Maryland, and colleagues examined the association between reproductive and menstrual factors and gastric cancer risk in a large study of 74,442 women from Shanghai, China.

Later age at menopause was associated with a markedly reduced risk of gastric cancer, the researchers report, and so was increased duration of fertility.

On the other hand, increased years since menopause and intrauterine device (IUD) use were associated with an increased risk of gastric cancer.

Number of children, breast feeding, or oral contraceptive use had no bearing on the risk, the report indicates.

"Our results were consistent with those of previous studies in other countries," the investigators say, and are "consistent with the hypothesis that hormones such as estrogen and progesterone protect against the development of gastric cancer in women during the reproductive years."

"In future studies, we plan to directly test this hypothesis by determining whether...hormone levels predict gastric cancer risk," Freedman said.

SOURCE: Gut, December 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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