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Recent News and Articles on the Keywords: test + ibs + overgrowth  Related to the article below (Last Update: 8/5/2008)

Bitter sweet
Melbourne Herald Sun, Australia - Aug 2, 2008
Around one in seven Australians suffer from IBS, and many attempt to manage the condition by ?eating well?. But it?s now known that, in many cases, ...
Evaluation of the Birmingham IBS symptom questionnaire.
7thSpace Interactive (press release), NY - Jul 23, 2008
Validity was assessed by comparing symptom scores with concurrent IBS specific quality of life (QoL) scores. Reproducibility was measured by the test-retest ...
Performance in Changeable Conditions
Tire Review, OH - Jul 28, 2008
The tread?s IBS (Interactive Brickwork Siping), siping laid out in a brickwork pattern, fulfills a dual role: it increases both lateral and longitudinal ...
Patients suffer from painful bladder problem with no cure
Spartanburg Herald Journal (subscription), SC - Jul 22, 2008
Some patients not only suffer from IC, but they also have irritable bowel syndrome (IBS), fibromyalgia or lupus. "It's almost like your body attacks itself ...
Luxoft Acquires Romania's ITC Networks
MarketWatch - Jul 22, 2008
Luxoft, a member of the IBS Group, is an emerging global leader in application and product engineering outsourcing services for enterprise IT organizations ...TYO:9422
The Heller Gun Decision Week Four
California Progress Report, CA - Jul 26, 2008
In California, there are a limited number of IBS terminals located throughout California. Most of them are located in large population and crime centers ...
The Sports Network Partners With Contec to Fuel BUZmob Mobile ...
Market Wire (press release) - Jul 28, 2008
TSN clients include Google, IBS/NBC, Tribune Interactive, Knight-Ridder Digital, LexisNexis, Westwood One, New York Times, Denver Post, LA Times, ...
SCOREBOARD: GSE gloom
Business Spectator, Australia - Jul 14, 2008
Today, we have a key inflation test locally ? Kiwi CPI makes or breaks the case for a July rate cut. Part of the RBNZ formula for a rate cut was slower ...
TheStreet.com Q2 2008 Earnings Call Transcript
Seeking Alpha, NY - Jul 31, 2008
We continue to want to be opportunistic in testing a lot of these things so yes we did test some of those behaviors with Vibrant to see how it worked. ...TSCM
Feeling batter with wheat-free treat
expressandstar.com, UK - Jul 8, 2008
?Around eight years ago I started having IBS symptoms but they just got worse and worse. ?My doctor suggested I had an allergy test and the results were a ...
Source: Google News

Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome -
M Pimentel, EJ Chow, HC Lin - American Journal of Gastroenterology, 2000 - Blackwell Synergy
... 2005) Detection of Bacterial Overgrowth in IBS Using the Lactulose H2 Breath Test:
Comparison with ... fructose and sorbitol in irritable bowel syndrome may be ...

… of MMC Is Found in IBS Subjects with Abnormal Lactulose Breath Test, Suggesting Bacterial Overgrowth -
M Pimentel, EE Soffer, EJ Chow, Y Kong, HC Lin - Digestive Diseases and Sciences, 2002 - Springer
... described an association between irritable bowel syndrome (IBS) and abnormal lactulose
breath test, suggesting small intestinal bacterial overgrowth (SIBO). ...

Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel … -
M Pimentel, EJ Chow, HC Lin - American Journal of Gastroenterology, 2003 - Blackwell Synergy
... Gut; the Evolving Role of the Enteric Flora in IBS. ... 2005) Hydrogen glucose breath
test to detect ... a prevalence case?control study in irritable bowel syndrome. ...

Detection of Bacterial Overgrowth in IBS Using the Lactulose H2 Breath Test: Comparison with 14C-d- … -
B Walters, SJ Vanner - The American Journal of Gastroenterology, 2005 - Blackwell Synergy
... reports suggest bacterial overgrowth is commonly associated with irritable bowel
syndrome (IBS) when diagnosed using the lactulose hydrogen breath test (LHBT). ...

Small Intestinal Bacterial Overgrowth A Framework for Understanding Irritable Bowel Syndrome -
HC Lin - JAMA, 2004 - Am Med Assoc
... Context Irritable bowel syndrome (IBS), which affects 11% to 14% of the ... SIBO) may
explain bloating in IBS is supported ... of abnormal lactulose breath test in 84 ...

Hydrogen glucose breath test to detect small intestinal bacterial overgrowth: a prevalence case- … -
A LUPASCU, M GABRIELLI, EC LAURITANO, E … - Alimentary Pharmacology & Therapeutics, 2005 - Blackwell Synergy
... to evaluate lactose intolerance in irritable bowel syndrome correlates with ... of bacterial
overgrowth in IBS using the lactulose H 2 breath test: comparison with ...

Lactulose breath testing, bacterial overgrowth, and IBS: just a lot of hot air? -
WL Hasler - Gastroenterology, 2003 - Elsevier
... The pathogenesis of irritable bowel syndrome (IBS) is poorly understood ... trial of
antibiotic therapy in IBS patients and ... symptoms to lactulose breath test results ...

Small intestinal bacterial overgrowth in patients with irritable bowel syndrome -
I Posserud, PO Stotzer, ES Bj?rnsson, H … - British Medical Journal, 2007 - gut.bmj.com
... breath test; IBS, irritable bowel syndrome; LHBT, lactulose hydrogen breath test;
MMC, migrating motor complex; SIBO, small intestinal bacterial overgrowth. ...

… and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth -
G Nucera, M Gabrielli, A Lupascu, EC Lauritano, A … - Alimentary Pharmacology & Therapeutics, 2005 - Blackwell Synergy
... (2007) Quick Test: A New Test for the ... Treatment and Retreatment of Bacterial Overgrowth
in IBS. ... (2006) Bacteria and irritable bowel syndrome: The evidence for ...

A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose … -
M Pimentel, D Wallace, D Hallegua, E Chow, Y Kong, … - British Medical Journal, 2004 - ard.bmj.com
... Abbreviations: IBS, irritable bowel syndrome; LBT, lactulose breath test;
SIBO, small intestinal bacterial overgrowth. Fibromyalgia ...

Source: Google Scholar

Breath test can discriminate between a bacterial overgrowth and IBS

The gastrointestinal (GI) tract is colonized by bacteria immediately after birth; Escherichia coli, Streptococci and Clostridi are the first bacteria harboured by the colon, followed by anaerobic Enterococci, Lattobacilli and Bacteroidi. These commensal bacteria inhabiting the human intestine (i.e., intestinal microflora) participate in the development and maintenance of gut sensory and motor functions, including the promotion of intestinal propulsive activity; on the other hand, intestinal motility represents one of the major control systems of gut microflora, though the sweeping of excessive bacteria from the lumen. There is emerging evidence indicating that changes in this bi-directional interplay contribute to the pathogenesis of gut diseases, such as small intestinal bacterial overgrowth (SIBO).

Many factors affect the type and distribution of the bacteria along the GI tract, starting from the type of delivery and nursing in the first days of life, up to the food habits during the adult life: a SIBO is often present in adult population of westernized countries, because of poor daily intake of fibres and faecal stasis; such an overgrowth contributes to a chronic inflammation on intestinal mucosa and development of symptoms, such as abdominal pain, diarrhoea or stipsis.

These symptoms look like those of inflammatory bowel diseases (IBS) and, unfortunately, most of these patients with a bacterial overgrowth are inappropriately treated with topically-active non-steroidal anti-inflammatory agents. In fact, these compounds have no antibacterial activity and, therefore, they do not remove the causative factors of the symptoms (bacterial overgrowth) and are likely to provoke even severe adverse events.

The "breath test" is a recently developed test, which is able to detect elevated concentrations of hydrogen in the expired air. In presence of a SIBO, dietary carbohydrates are metabolised with production of massive amounts of hydrogen that are eliminated with the breath. Thus, the "breath test" consists in administering 50-75 grams of lactulose and assaying the concentrations of hydrogen in the expired air; if these concentrations exceed 10 to 20 part per million, the subject is suspected to have a SIBO and should be appropriately treated with antibiotics.

Clinicians should be encouraged to perform a "breath test" to promptly identify a bacterial overgrowth, because the disorder has several systemic consequences ranging from malabsorption of lipids and liposoluble vitamins and loss of electrolytes, to a more severe translocation of bacteria (usually, gram-negative and aerobic bacteria, such as Escherichia, Proteus, Enterobacter and Klebsiella) from the GI tract to extraintestinal tissues; all these factors may lead to sepsis and multiorgan failure.

Today, there is an effective treatment for bacterial overgrowth, which is rapidly corrected by the use of locally acting non-absorbable antibiotics, such as rifaximin polimorph A, which reverses the process (intestinal bacterial overgrowth) and prevents the cascade of events leading from intestinal low-grade inflammation to symptom development.
 
 
 
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