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Recent News and Articles on the Keywords: copd + 0.39 + web  Related to the article below (Last Update: 8/5/2008)

Long acting beta agonists first for COPD
6minutes, Australia -
by Michael Woodhead The first evidence that drug treatment can slow the decline in lung function in COPD has come from a major multinational study that ...
Study Shows that COPD Patients Do Not Know About Their Disease
PR-USA.net (press release), Bulgaria - Aug 4, 2008
the authors found that most COPD patients have little to no knowledge about the disease. According to their research published in the journal Lung, Parker, ...
Creatine a Bust for Boosting Exercise Benefit in COPD
MedPage Today, NJ - Aug 4, 2008
4 -- Creatine supplements added to exercise failed to give any benefits to COPD patients, researchers here said. Explain to interested patients that ...
Creatine Has Negligible Effect on COPD Exercise Rehab
Washington Post, United States - Aug 1, 2008
1 (HealthDay News) -- Taking creatine doesn't improve exercise outcomes in people who have chronic obstructive pulmonary disease (COPD), a UK study reports. ...
Creatine not recommended for improving COPD outcomes Nursing Times
all 23 news articles »
VitalAire wins 5-year contracts to become primary provider of ...
Canada NewsWire (press release), Canada -
Home oxygen therapy is often required for severe COPD. The use of supplemental oxygen, including portability options, allows these patients to increase ...OTC:AIQUY
Muscle strength boosting supplement ?doesn?t help? COPD patients
Newspost Online, India - Aug 3, 2008
?We have evidence to suggest Cr uptake into muscles [in COPD patients] but are unable to explain why an increase in muscle Cr did not enhance training,? ...
Chest Journal: August news briefs
EurekAlert (press release), DC -
Researchers from Ireland administered three health-related quality of life (HRQoL) questionnaires to 147 outpatients (chronic cough, n=83; COPD, n=18; ...
docwright.com cures ills
Gold Coast News, Australia -
A: It is not asthma, its not bronchitis, not emphysema, but a rarely discussed condition called COPD. This is short for Chronic Obstructive Airway Disease, ...
Cash Needed to Fight Disease
RedOrbit, TX -
And COPD, chronic obstructive pulmonary disease and an umbrella term for bronchitis and emphysema, is one of the few chronic conditions which is on the ...
Respiratory Research Nurse
Nursing Times, UK -
This post involves considerable clinical involvement and the post holder will coordinate the running of the London COPD study cohort on a daily basis. ...
Source: Google News

Efficacy of Salmeterol Xinafoate in the Treatment of COPD* -
DA Mahler, JF Donohue, RA Barbee, MD Goldman, NJ … - Chest, 1999 - Am Coll Chest Phys
... Search for citing articles in: ISI Web of Science (100). ... in a new window], Table
2. COPD History and ... and ipratropium groups (0.434 ? 0.07 to 0.39 ? 0.06; p ...

Health status measurement in COPD: the minimal clinically important difference of the clinical COPD -
JW Kocks, MG Tuinenga, SM Uil, JW van den Berg, E … - Respir Res, 2006 - respiratory-research.com
... Thus, it can be concluded that when a difference in CCQ score between two patients
with COPD exceeds 0.39 points, the patient with the higher score has an ...

… -Controlled Study Comparing Lung Function and Health Status Changes in COPD Patients Treated With … -
JF Donohue, JA van Noord, ED Bateman, SJ Langley, … - Chest, 2002 - Am Coll Chest Phys
... Search for citing articles in: ISI Web of Science (11 ... had a significant disease other
than COPD were also ... was as follows: tiotropium, 1.11 ? 0.39 L; salmeterol ...

What Outcomes Should Be Measured in Patients With COPD? -
RD Yusen - Chest, 2001 - Am Coll Chest Phys
... Search for citing articles in: ISI Web of Science (6). ... change in the SF-36 PCS-
[r = 0.39; p < 0.001 ... For patients with symptomatic COPD, measures of HRQL provide ...

Dynamic hyperinflation and tolerance to interval exercise in patients with advanced COPD -
I Vogiatzis, S Nanas, E Kastanakis, O Georgiadou, … - European Respiratory Journal, 2004 - Eur Respiratory Soc
... capacity (IC) was measured to reflect changes in DH in 27 COPD patients (forced ...
tolerance in both IE and CLE, patients exhibited similar DH ( IC: 0.39?0.05 L ...

Efficacy and Safety of a Monoclonal Antibody Recognizing Interleukin-8 in COPD* A Pilot Study -
DA Mahler, S Huang, M Tabrizi, GM Bell - Chest, 2004 - Am Coll Chest Phys
... The proportion of patients with treatment-emergent COPD exacerbation was compared
between ABX-IL8 and ... group and 25 ? 5 pg/mL in the ABX-IL8 group (p = 0.39). ...

Sleep arterial oxygen desaturation and chemical control of breathing during wakefulness in COPD -
K Tatsumi - Chest, 1986 - Am Coll Chest Phys
... be found online on the World Wide Web at: The ... Most COPD patients were being treated
with awide variety of ... 2IASa0, varied from - 0.04 to - 0.39 cm H201% with ...

The 6-min walk distance: change over time and value as a predictor of survival in severe COPD -
VM Pinto-Plata, C Cote, H Cabral, J Taylor, BR … - European Respiratory Journal, 2004 - ersj.org.uk
... The majority of the patients in the COPD group were male (83 ... m?yr ?1 . Similarly,
there was a decrease in FEV 1 (group 1) from 1.13?0.40 L to 0.98?0.39 L (p ...

Plasma Orexin-A Levels and Body Composition in COPD* -
T Matsumura, M Nakayama, H Satoh, A Naito, K … - Chest, 2003 - Am Coll Chest Phys
... Similar articles found in: Chest Online ISI Web of Science ... of predicted (bottom right,
D) in patients with COPD. Neither BMI (r = 0.39, p = 0.09) [top left, A ...

… Associated With Noninvasive Ventilation in Patients With Exacerbation of COPD and Pulmonary Edema -
E Girou, C Brun-Buisson, S Taille, F Lemaire, L … - JAMA, 2003 - Am Med Assoc
... associated with ICU outcome (Table 3). The risk of death was 3-fold lower in patients
with COPD or CPE who had received NIV (adjusted OR, 0.39; 95% CI, 0.19 ...

Source: Google Scholar

When Disease Discriminates: Women And COPD

Women have made a good deal of welcome progress in the last several decades, but at least one advance is unwanted: chronic obstructive pulmonary disease (COPD) is on the rise in women in prevalence, morbidity and mortality. By 2000, the number of women dying from COPD surpassed the number of men. But the rising number of cases in women has not been matched by medical understanding of the disease's apparent gender-bias.

"The disease expression of COPD in women is different than in men," says Fernando Martinez, M.D., professor of internal medicine at the University of Michigan and senior author on the review, which appears in the second issue for December of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society. "The main reason that we did this study was to highlight that there really are gender differences in the disease, and that they require additional study."
Dr. Martinez and his colleagues assessed the state of medical and scientific knowledge on gender and COPD and found some consistent patterns. Not only are the manifestations of the disease different in men and women, but the risk factors, symptoms, disease, progression, and even diagnosis, are markedly different between the sexes.

COPD actually comprises what used to be considered two distinct diseases: emphysema, or an abnormality in the lung tissue, and chronic bronchitis, an obstruction of the airways. One of the major gender differences in the manifestation of COPD is that women tend to develop more airway obstruction, whereas men tend to develop a more emphysematic manifestation of the disease. But why that is so is still unclear.

"It may reflect differences in exposures, or [genetic] differences in how males and females manifest damage," said Dr. Martinez. "Or it may have nothing to do with underlying genetic differences that are gender-based."

Women also seem to more prone than men to developing COPD from their exposures to risk factors, such as cigarette smoke and smoke from biomass fuels used for cooking in many developing regions of the world. Ironically, a number of studies have also shown that female smokers have a harder time quitting and remaining tobacco-free than males. Because COPD can develop over decades, a significant portion of current cases can be traced back to a rising smoking epidemic among women that began in the 1950s.

Women may be more susceptible to developing COPD from their exposures, but they also predominate among COPD patients who have never smoked, and may have gender-linked genetic factors that predispose them to developing the disease.

And once sick, women also have different experiences than men. They are less likely to be correctly diagnosed or offered appropriate diagnostic tests for COPD. They report more severe shortness of breath, more anxiety and depression. And according to some studies, they report having a lower quality of life because of their disease.

The fact that COPD differs between men and women is undisputed. But answering questions as to how and why, Dr. Martinez emphasizes, is critical in advancing the medical and scientific understanding of the disease. How do men and women differ in exposures and other risk factors? Are the differences biological or behavioral? How do exposure patterns affect their susceptibility to developing the disease and its manifestation? Why does COPD progress more swiftly in women? Do outcomes differ because of gender bias in diagnosis, physiological differences, or phenotypic differences in their disease?

"Whatever the question, whether it is about the biological nature of the disease or clinical impact of therapeutic studies, you have to have a gender analysis," says Dr. Martinez. "It's an absolutely crucial parameter. Appropriate gender analysis has to be taken into account because it may be instrumental in allowing you to interpret what you're trying to study."

Founded in 1905, the American Thoracic Society is the world's leading medical association dedicated to advancing pulmonary, critical care and sleep medicine. The Society has more than 18,000 members who prevent and fight respiratory disease around the globe, through research, education, patient care and advocacy.

American Thoracic Society
 
 
 
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