-
M Angell - Jurimetrics, 2004 - HeinOnline
... not important new drugs, but minor variations of drugs already on the market--called
"me-too" drugs. For example, the top-selling drug in the world, Pfizer's ...
The druggable genome -
AL Hopkins, CR Groom - Nat Rev Drug Discov, 2002 - jade.botany.utoronto.ca
... NCE, new chemical entity ... The limited number of small-molecule drug targets suggests
that to ... Informatics, Structure and Design Department, Pfizer Global Research ...
The price of innovation: new estimates of drug development costs -
JA DiMasi, RW Hansen, HG Grabowski - Journal of Health Economics, 2003 - Elsevier
... These data were used to estimate the average pre-tax cost of new drug development. ...
The chart also shows the number of US new drug approvals by year. ...
The making of a disease: female sexual dysfunction -
R Moynihan - BMJ, 2003 - pubmedcentral.nih.gov
... a new category of human illness at meetings heavily sponsored by companies racing
to develop new drugs. The most recent gathering, featured Pfizer as chief ...
Social Relations and Innovation in the Medical Profession: The Epidemiology of a New Drug -
H Menzel, E Katz - Public Opinion Quarterly, 1955 - JSTOR
... Medical Profession: The Epidemiology of a New Drug* By HERBERT ... and ELIHU KATZ A study
of drug adoptions by ... Pfizer & Co., Inc., manufacturers of chemicals and ...
… computational approaches to estimate solubility and permeability in drug discovery and development … -
CA Lipinski, F Lombardo, BW Dominy, PJ Feeney - Advanced Drug Delivery Reviews, 2001 - Elsevier
... is now the major, rich source of drug discovery leads ... At the Pfizer Groton site,
we have retrospectively examined the ... further jump in 1992 to a new stable MWT ...
IGF-1: Old Growth Factor Shines as New Drug Target -
K Garber - jnci, 2005 - jnci.oxfordjournals.org
... launched a phase I trial of a new monoclonal antibody against cancer. The target:
the insulin-like growth factor 1 (IGF-1) receptor. Pfizer's drug was the ...
… Ischemic Optic Neuropathy Developing Soon After Use of Sildenafil (Viagra): A Report of Seven New … -
HD Pomeranz, AR Bhavsar - Journal of Neuro-Ophthalmology, 2005 - jneuro-ophthalmology.com
... Sildenafil citrate (Viagra; Pfizer Pharmaceuticals, New York, NY ... the most frequently
reported adverse events associated with use of this drug. ...
VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES -
RL Walsky, RS Obach - Drug Metabolism and Disposition, 2004 - ASPET
... Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer, Inc., Groton,
Connecticut. The measurement of the effect of new chemical entities on human ...
STATISTICS: Bayes Offers a'New'Way to Make Sense of Numbers -
D Malakoff - Science, 1999 - sciencemag.org
... The Pfizer study, in contrast, should allow researchers to analyze the accumulating
data and ... In a trial comparing a new drug to no treatment, for instance, a ...
Source: Google Scholar |