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Recent News and Articles on the Keywords: support + web + 0.38  Related to the article below (Last Update: 8/5/2008)

Henry Schein Reports Record Second Quarter Results
Trading Markets (press release), CA -
Individual investors are invited to listen to the conference call over the Internet through Henry Schein's Web site at www.henryschein.com. ...HSIC
GFI Group Inc. Announces Second Quarter 2008 Results; Declares ...
MarketWatch - Jul 31, 2008
A live audio web cast of the conference call will be available on the Investor Relations section of GFI's Web site. For web cast registration information, ...GFIG
Littelfuse Reports Second Quarter Results
MarketWatch - Jul 30, 2008
Capital expenditures increased as expected in the second quarter of 2008 to $13.6 million, mostly to support the manufacturing transfers. ...LFUS
SAP Reports Strong Growth in Software and Software-Related Service ...
FOXBusiness - Jul 29, 2008
Non-GAAP earnings per share from continuing operations for the second quarter of 2008 was 0.42 euro (2007: 0.38 euro), which was an increase of 11% compared ...SAP - AG - OTC:CMTX
Partner Communications Reports Second Quarter 2008 Results
MarketWatch - Jul 31, 2008
The Board has approved the distribution of a dividend for Q2 2008 of NIS 1.26 (US$ 0.38) per share (in total approximately NIS 200 million or US$ 60 ...PTNR
Human Genome Sciences Announces Second Quarter 2008 Financial ...
MarketWatch - Jul 30, 2008
The first Phase 3 data are expected by mid-2009, and all Phase 3 data to support regulatory filings are expected in fall 2009. It is anticipated that a BLA ...HGSI
EarthLink Announces Second Quarter Results
PR Newswire (press release), NY - Jul 29, 2008
While this focus on higher value, but fewer subscribers resulted in a decline in revenues, these tenured users also demonstrated significantly lower support ...ELNK - WAR:CFL
IMA's Island Copper Project Moving Forward
FOXBusiness - Jul 24, 2008
Most importantly the Company is putting in place the required team and logistics support required to begin exploration activity on the project and advance ...IMR - OTC:CMTX
Nalco Continues Delivering Rapid Revenue Growth
Trading Markets (press release), CA - Jul 29, 2008
Information on the conference call and Webcast is available on our Web site at www.nalco.com Nalco is the world's leading water treatment and process ...NLC - OTC:CMTX
XM Satellite Radio Holdings Inc. Announces Second Quarter 2008 Results
Earthtimes (press release), UK - Jul 22, 2008
XM programming is also available through XM Radio Online, as downloads of original XM shows via podcasts from XM's Web site or the Apple's iTunes Store, ...XMSR
Source: Google News

World-Wide-Web technology in support of negotiation and communication -
J Teich, H Wallenius, J Wallenius - International Journal of Technology Management, 1999 - Inderscience
... of the respondents would be willing to use negotiation support tools if ... technology
and perceived company-wide usage of web technology (0.38, p-value ...

How the Semantic Web is Being Used: An Analysis of FOAF Documents -
L Ding, L Zhou, T Finin, A Joshi - System Sciences, 2005. HICSS'05. Proceedings of the 38th …, 2005 - ieeexplore.ieee.org
... engines is that they do not fully support meta search, ie ... are 5,000 documents from
non-blog web sites in ... 0.44) foaf:weblog (0.99) foaf:mbox (0.38) rdfs:seeAlso ...

Filter device -
SB Linnersten - EP Patent 0,383,525, 1994 - freepatentsonline.com
... on in-turned frame edge members 3. Additional support is provided by a support member
4 ... The combined thickness of the filter sheet and web is 0.38 mm (0.015 ...

Evaluation of an internet support group for women with primary breast cancer -
AJ Winzelberg, C Classen, GW Alpers, H Roberts, C … - Cancer, 2003 - doi.wiley.com
... RESULTS. The results indicate that a web-based support group can be useful in reducing
depression and cancer ... The effect sizes ranged from 0.38 to 0.54. ...

Web Usage Mining Using Support Vector Machine -
SH Jun - Lecture Note in Computer Science, 2005 - Springer
... Web Usage Mining Using Support Vector Machine ... P(High|High) 0.41 0.35 0.33 P(Low|Low)
0.38 0.31 0.29 ... was showed the probability of visited High(web pages) after ...

Process for the transformation of a comminuted swellable cellulose ether into an easily workable … -
L Grosse, HW Dorr - US Patent 4,069,082, 1978 - freepatentsonline.com
... In addition, a hydrophilic web material having the same composition as ... be laminated
onto the coated side of the support. ... wet state, ie it has absorbed 0.38 g of ...

Rough set clustering for Web mining -
P Lingras - Fuzzy Systems, 2002. FUZZ-IEEE'02. Proceedings of the 2002 …, 2002 - ieeexplore.ieee.org
Page 1 0-7803-7280-8/02/$ 10.00 ?2002 IEEE 1039 Rough Set Clustering for Web Mining
Pawan Lingras Saint Mary?s University Halifax, Nova Scotia, B3H 3C3 ...

Quality of web based information on treatment of depression: cross sectional survey -
KM Griffiths - BMJ, 2000 - pubmedcentral.nih.gov
... not differ significantly (mean difference 0.38 (SD 1.5 ... teaching centres disseminated
inadequate reviews on the web. ... is some evidence to support this criticism ...

Support for the Lunar Cataclysm Hypothesis from Lunar Meteorite Impact Melt Ages -
BA Cohen, TD Swindle, DA Kring - Science, 2000 - sciencemag.org
... using a browser that does not support current Web standards. ... Support for the Lunar
Cataclysm Hypothesis from Lunar Meteorite Impact Melt ... DaG 400, 2.76 (0.38), 7. ...

Development and application of a livable environment evaluation support system using Web GIS -
A Sakamoto, H Fukui - Journal of Geographical Systems, 2004 - Springer
... Development and application of a livable environment evaluation support
system using Web GIS Ai Sakamoto 1 and Hiromichi Fukui 2 ...

Source: Google Scholar

Breakthrough Technology Observes Synapse in Real Time, Supporting Theory of Vesicular Recycling

Weill Cornell Scientists Use Cutting-Edge Methods to Show That Neurotransmitter Packets Must Be Rebuilt After Each Cycle
NEW YORK (Dec. 13, 2007) — For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

In doing so, they've also laid to rest a competing theory as to how key cellular processes—called endocytosis and exocytosis—work.

The scientists published their findings in this week's online edition of Proceedings of the National Academy of Sciences (Dec. 18 print edition).

Healthy neurological function hinges on the efficient passage of information between brain cells via the synapse, and exocytosis/endocytosis is the complex trafficking mechanism that allows this to happen.

At its simplest level, exocytosis involves the packaging, transport and delivery of neurotransmitter chemicals in sac-like structures called vesicles. These vesicles move from the interior of the cell to the cell membrane, where they deliver their information-rich cargo to the synapse. Endocytosis involves a similar function in the reverse direction, with incoming vesicles being transported into the cell's interior.
The vesicles aren't discarded, however. Instead, once they release their cargo they are recycled for use in another go-round. There have been two competing theories about how that recycling occurs—either the vesicle fragments upon delivering its cargo and must be rebuilt, or it simply empties itself like milk from a bottle which is then resealed.

"The vast bulk of the evidence suggests the former theory is actually the correct one, but it's been tempting to think of the 'resealable spout' theory, because it seems so logical and because there's been some ambiguous evidence that it might be true," says the study's co-author Dr. Timothy Ryan, professor of biochemistry at Weill Cornell Medical College.

The trouble is, no one had ever found a way to observe—accurately and in real time—synaptic vesicle recycling as it occurs.

That has changed with this new paper. "We have taken advantage of recent advances in fluorescent 'tagging' of molecules involved in these cellular processes, as well as new microscopy technologies that give us an incredible new ability to watch all of this, up close and in real-time," says Dr. Ryan.

Specifically, Dr. Ryan used a fluorescent chemical stain called pHluorin and genetically fused it to a vesicular protein called vGlut1. "We've used this fluorescent tagging approach before, but with molecules that can exist on either the outside or the inside of the vesicle," Dr. Ryan notes.

"VGlut1 gives us a much more precise view, since it only inhabits the inside of the vesicle," he adds. "That means that when we see the green fluorescent tag move outside of the vesicle, then the vesicle itself must have ruptured in some way. This gives us a much more accurate picture of the recycling process."

At the same time, the team took advantage of new breakthroughs in optical microscopy that maximize how much of the tag's fluorescent light can be "grabbed" by the microscope. This approach allowed them, for the first time, to follow how individual synaptic molecules are delivered and retrieved from the synaptic surface.

"The result is an accurate view into this hitherto mysterious synaptic phenomenon," Dr. Ryan says.

The "resealable spout" hypothesis of vesicular recycling (also known as the "kiss-and-run" theory) may be the first casualty of this new insight.

"We observed that, although recycling appears to occur within a set but somewhat variable time-frame, it's still using the same mechanism—the vesicle falls apart upon delivering its cargo to the cell membrane, and then enzymes go to work re-building it for the next cycle," Dr. Ryan adds. "I think this real-time observation really closes the door on the 'kiss-and-run' theory of vesicular recycling."

The new technology used in these experiments should bring scientists much more insight into how the synapse works generally, and that could have real implications for our understanding of neurological health and illness, Dr. Ryan says.

"This is all part of the 'shop manual' of neurological function that we are currently putting together, piece by piece," he says. "Discoveries like these are adding new pages to the manual every day, and it's that kind of knowledge that will someday save, extend and improve lives."

The study was co-authored by Dr. J. Balaji, who conducted the work while at Weill Cornell. Dr. Balaji has since moved to the University of California, Los Angeles.

This work was funded by grants from the U.S. National Institutes of Health.


Weill Cornell Medical College


Weill Cornell Medical College—Cornell University's Medical School located in New York City—s committed to excellence in research, teaching, patient care and the advancement of the art and science of medicine, locally, nationally and globally. Weill Cornell, which is a principal academic affiliate of NewYork-Presbyterian Hospital, offers an innovative curriculum that integrates the teaching of basic and clinical sciences, problem-based learning, office-based preceptorships, and primary care and doctoring courses. Physicians and scientists of Weill Cornell Medical College are engaged in cutting-edge research in such areas as stem cells, genetics and gene therapy, geriatrics, neuroscience, structural biology, cardiovascular medicine, infectious disease, obesity, cancer, psychiatry and public health—and continue to delve ever deeper into the molecular basis of disease in an effort to unlock the mysteries behind the human body and the malfunctions that result in serious medical disorders. The Medical College—in its commitment to global health and education—has a strong presence in such places as Qatar, Tanzania, Haiti, Brazil, Austria and Turkey. With the historic Weill Cornell Medical College in Qatar, the Medical School is the first in the U.S. to offer its M.D. degree overseas. Weill Cornell is the birthplace of many medical advances—from the development of the Pap test for cervical cancer to the synthesis of penicillin, the first successful embryo-biopsy pregnancy and birth in the U.S., the first clinical trial for gene therapy for Parkinson's disease, the first indication of bone marrow's critical role in tumor growth, and, most recently, the world's first successful use of deep brain stimulation to treat a minimally-conscious brain-injured patient. For more information, visit www.med.cornell.edu.

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