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Recent News and Articles on the Keywords: news + medicine + hopkins  Related to the article below (Last Update: 8/5/2008)


Chatter Shmatter
For Psychiatrists, Talk Therapy Falling by Wayside
Washington Post, United States -
... at Johns Hopkins Bloomberg School of Public Health in Baltimore. Mojtabai was affiliated with Beth Israel Medical Center while completing the study. ...
Can Medication Replace Talk Therapy? eFluxMedia
In era of pills, fewer shrinks doing talk therapy The Associated Press
Medication increasingly replaces psychotherapy, study finds Los Angeles Times
all 273 news articles »
Virtua Cardiologists Respond to Commentary on Angioplasty
MarketWatch -
Every hospital in the multi-state elective angioplasty program is overseen by four independent levels of monitoring -- Johns Hopkins Medical Institutions, ...
Screening: Higher Rates of Hearing Loss Are Found
New York Times, United States -
The researchers, who were led by Dr. Yuri Agrawal of Johns Hopkins, looked at the data from a federal study of more than 5700 people ages 20 to 69. ...
Personal Health Sorting Out Coffee?s Contradictions New York Times
all 4 news articles »

Johns Hopkins Gazette
Remembering Victor McKusick
Johns Hopkins Gazette, MD - Aug 4, 2008
"We have lost a giant," said Edward D. Miller, dean of the medical faculty and chief executive officer of Johns Hopkins Medicine. "He spent virtually all of ...
Small is beautiful and very useful
Irish Times, Ireland -
... medical centres including the John Hopkins, the Mayo Clinic and the Cleveland Clinic in the US and a small number of other centres in other countries. ...
Medical people
The Ledger, FL -
She attended medical school at Johns Hopkins University School of Medicine. She did her residency in general surgery at Huntington Memorial Hospital in ...
Hopkins community raises funds for cancer victim
Maryville Daily Forum, MO -
?There have been so many advances in medicine and technology in the last few years,? she said. ?I feel like things will be fine. St. Luke?s is a great place ...
Crunch time for peanut allergies
Independent, UK -
Doctors at Johns Hopkins Children's Centre, Baltimore, and Arkansas Children's Hospital, who studied 80 youngsters aged from four to 14 with peanut allergy, ...
Like Eavesdropping At A Party: How A Tiny Protein Senses All The ...
Science Daily (press release) - Aug 1, 2008
Reporting in the June 27 issue of Cell, a team of biomedical engineers at the Johns Hopkins School of Medicine has discovered how the calcium sensor protein ...
New Uses for Old-Line Diabetes Test: Screening and Diagnosis
Johns Hopkins Gazette, MD - Aug 4, 2008
... of endocrinology and metabolism at the Johns Hopkins University School of Medicine and director of the Johns Hopkins Comprehensive Diabetes Center. ...
Source: Google News

Perioperative antibiotic prophylaxis for herniorrhaphy and breast surgery -
R Platt, DF Zaleznik, CC Hopkins, EP Dellinger, AW … - N Engl J Med, 1990 - Mass Med Soc
... publishers of The New England Journal of Medicine. Save time and stay informed.
Our physician-editors offer you clinical perspectives on key research and news. ...

Latent infection of CD4 T cells provides a mechanism for lifelong persistence of HIV-1, even in … -
D Finzi, J Blankson, JD Siliciano, JB Margolick, K … - Nat Med, 1999 - palgrave-journals.com
... Siliciano 1 1 Department of Medicine, Johns Hopkins University School of
Medicine, Baltimore Maryland 21205, USA. 2 Department of ...

Navigating chemical space for biology and medicine -
C Lipinski, A Hopkins - Nature, 2004 - nature.com
... Horrobin, DF Modern biomedical research: an internally self-consistent universe
with little contact with medical reality. ... | PubMed | ChemPort |; Hopkins, AL & ...

Single pass sequencing and physical and genetic mapping of human brain cDNAs -
… , MH Polymeropoulos, JA Hopkins, TJ Stevens, M … - Nature Genetics, 1992 - palgrave-journals.com
... REFERENCES: Wilcox, AS, Khan, AS, Hopkins, JA & Sikela, JM Use of 3' untranslated
sequences of human cDNAs for rapid chromosome ... Human Genome News 2 (5) 9 (1991 ...

The association of an HPV 16 oncogene variant with HLA-B 7 has implications for vaccine design in … -
… , DV Renouf, M Rowe, D Hopkins, MF Duggan-Keen, JS … - Nature Medicine, 1995 - nature.com
... Nature Medicine 1, 464 - 470 (1995) doi:10.1038/nm0595-464 ... Ellis 1 , PJ Keating 2 ,
J. Baird 1 , EF Hounsell 3 , DV Renouf 3 , M. Rowe 1 , D. Hopkins 1 , MF ...

The Bardet-Biedl protein BBS 4 targets cargo to the pericentriolar region and is required for … -
JC Kim, JL Badano, S Sibold, MA Esmail, J Hill, BE … - Nature Genetics, 2004 - palgrave-journals.com
... 3 Molecular Medicine Unit, Institute of Child Health, University College London ... 5
Wilmer Eye Institute, Johns Hopkins University, 600 North Wolfe ... NEWS AND VIEWS. ...

Intravenous ketamine for pediatric sedation in the emergency department: safety profile with 156 … -
… , SG Rothrock, T Harris, GA Hopkins, W Garrett, T … - Acad Emerg Med, 1998 - Mass Med Soc
... publishers of The New England Journal of Medicine. Save time and stay informed.
Our physician-editors offer you clinical perspectives on key research and news. ...

Rapid accumulation of genome rearrangements in liver but not in brain of old mice -
MET Dolle, H Giese, CL Hopkins, HJ Martus, JM … - Nature Genetics, 1997 - nature.com
... Martijn ET Doll? 1 , Heidi Giese 1 , Craig L. Hopkins 1 , Hans-J?rg ... Medical Center
and Harvard Medical School, Harvard Institutes of Medicine, 77 Avenue ...

DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21. 1 -
SA Hahn, M Schutte, ATM Hoque, CA Moskaluk, LT da … - Science, 1996 - sciencemag.org
... CA Moskaluk, E. Rozenblum, CL Weinstein, A. Fischer, RH Hruban, Department of Pathology,
Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. ...

The association between circumcision status and human immunodeficiency virus infection among … -
JK Kreiss, SG Hopkins - J Infect Dis, 1993 - Mass Med Soc
... physician-editors offer you clinical perspectives on key research and news. ... Published
in Journal Watch General Medicine December 14, 1993. ... Kreiss JK; Hopkins SG ...

Source: Google Scholar

Cell 'Addiction' to Growth Factors May Help Spur Cancers

Study in mice shows blocking this dependence could stop disease before it starts

(SOURCE: Johns Hopkins Medicine, news release, Dec. 10, 2007)

THURSDAY, Dec. 13 (HealthDay News) -- "Addiction" to certain growth factors contributes to the development of cancers caused by epigenetic changes, such as the inappropriate activation of a normally silent gene, scientists say.

The team of Johns Hopkins University researchers believe that blocking this addiction might help prevent cancer growth.

They compared mouse cells with only one copy of the IGF-II (insulin-like growth factor two) gene activated to mouse cells with both copies of IGF-II activated. Normally, only one copy of the IGF-II gene is activated.

In humans, activation of both IGF-II genes has been linked with a fivefold increased risk of intestinal tumors.

Mouse cells with one activated copy of the IGF-II gene responded to normal doses of IGF-II growth factor and recovered within 90 minutes. The cells with both copies of the IGF-II gene responded to the smallest doses of growth factor and stayed that way for more than 120 minutes.

Working with mice bred to develop colon cancer, the researchers then administered a drug that blocks the cell's ability to respond to IGF-II growth factor. The mice developed 70 percent fewer precancerous lesions than untreated mice.

"Finding the molecular mechanism behind cancer development allowed us to use a specific drug to actually take care of these risky cells before the animal developed cancer. It's making us think about cancer prevention in a whole new way," Dr. Andrew Feinberg, professor of medicine, oncology and molecular biology and genetics, and director of the Epigenetics Center at Hopkins, said in a prepared statement.

"If this is transferable to people, it could be really exciting," Feinberg said. "It means we might be able to do something about at-risk cells before cancer develops and treat these cells biochemically, and specifically, rather than using current drugs that are nonspecific and kill everything in their path."

The study was expected to be published online next week in the journal Proceedings of the National Academy of Sciences.

More information

The U.S. National Cancer Institute has more about cancer genetics.

 

 

 
 
 
 
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