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Recent News and Articles on the Keywords: epilepsy treatment + epilepsy + treatments  Related to the article below (Last Update: 8/5/2008)

NC's BioLink wins three patents for epilepsy treatment
TechJournal South, NC - Aug 4, 2008
Valproates are used for the treatment of epilepsy, bipolar disorders, and migraines. New uses of valproates as treatments for Alzheimer?s disease and cancer ...
Icagen Reports Second Quarter 2008 Financial Results
MarketWatch -
... ICA-105665 for epilepsy and senicapoc for asthma. We believe that both of these programs represent novel approaches to the treatment of important ...ICGN
Epilepsy Drug May Help Alcoholics Recover From Dependence, Small ...
Science Daily (press release) - Aug 4, 2008
Although the study involved only 21 insomniacs in recovery from alcohol dependence, and did not provide long-term gabapentin treatment or long-term ...
Epilepsy Drug Helps Alcoholics to Overcome Insomnia, Cravings
MedIndia, India -
Meanwhile, patients reported sleeping better in both the treatment and placebo groups, which may be due to the gabapentin in the first group and the ...
Marinus Pharmaceuticals Appoints John Krayacich as President and ...
Earthtimes (press release), UK -
It is currently being investigated in a Phase IIb clinical trial as a potential treatment of epilepsy in children (infantile spasms) and complex partial ...
Epilepsy Drug May Increase Risk Of Birth Defects
eMaxHealth.com, NC -
Maintaining effective epilepsy treatment during pregnancy is crucial because seizures may cause harm to the fetus. For the study, researchers examined women ...
Questcor Announces CFO Transition Plan
MarketWatch -
... childhood epilepsy, and opsoclonus myoclonus syndrome, a rare autoimmune-related childhood neurological disorder. Doral is indicated for the treatment ...QCOR
Lower expenses reduce Icagen?s 2Q loss
Bizjournals.com, NC -
The biggest reason for the lower expenses was the end of expensive, last-stage human trials for sickle-cell disease treatment senicapoc. ...
Icagen posts second-quarter losses News & Observer
all 5 news articles »  ICGN
LSU, West Jeff team on epilepsy treatment
New Orleans CityBusiness, LA - Jul 28, 2008
Louisiana State University Health Sciences Center New Orleans and West Jefferson Medical Center have teamed to provide epilepsy care for patients in the ...
July 29 - Aug. 7 New Orleans CityBusiness
all 2 news articles »
Medical posts unfilled, says trust
The Press Association - Aug 4, 2008
Services for those suffering from conditions such as epilepsy have been affected, with too much reliance on temporary doctors. The trust's Margaret Kelly ...
Source: Google News

Early Identification of Refractory Epilepsy -
P Kwan, MJ Brodie - New England Journal of Medicine, 2000 - content.nejm.org
... In 12 patients (3 percent) epilepsy was controlled by treatment with two drugs. ... When
should surgery be considered for the treatment of epilepsy?. ...

Multiple subpial transection: a new approach to the surgical treatment of focal epilepsy. -
F Morrell, WW Whisler, TP Bleck - J Neurosurg, 1989 - ncbi.nlm.nih.gov
... 1989 Oct;71(4):629-30. Multiple subpial transection: a new approach to the surgical
treatment of focal epilepsy. Morrell F, Whisler WW, Bleck TP. ...

Focal neuronal migration disorders and intractable partial epilepsy: results of surgical treatment. -
A Palmini, F Andermann, A Olivier, D Tampieri, Y … - Ann Neurol, 1991 - ncbi.nlm.nih.gov
Ann Neurol. 1991 Dec;30(6):750-7. Focal neuronal migration disorders and
intractable partial epilepsy: results of surgical treatment. ...

… and Tolerability of the New Antiepileptic Drugs, II: Treatment of Refractory Epilepsy: Report of the … -
JA French, AM Kanner, J Bautista, B Abou-Khalil, T … - Epilepsia, 2004 - Blackwell Synergy
... Efficacy and Tolerability of the New Antiepileptic Drugs, II: Treatment of Refractory
Epilepsy: Report of the TTA and QSS Subcommittees of the American Academy ...

Epilepsy in Developing Countries: A Review of Epidemiological, Sociocultural, and Treatment Aspects -
SD Shorvon, PJ Farmer - Epilepsia, 1988 - Blackwell Synergy
... The key to improvements in medical treatment lie with a better understanding of
the patients? cultural concepts of epilepsy and its treatment, improved drug ...

… -Controlled Trial of Topiramate (600 mg Daily) for the Treatment of Refractory Partial Epilepsy -
CA Tassinari, R Michelucci, P Chauvel, J … - Epilepsia, 1996 - Blackwell Synergy
... to have documented re- fractory partial epilepsy. ... 2). The difference between the
treatments was statistically ... the TPM group were treatment responders (patients ...

Cognitive and Behavioral Effects of Epilepsy Treatment -
DW Loring, KJ Meador - Epilepsia, 2001 - Blackwell Synergy
... Uvebrant P, Bauziene R. Intractable epilepsy in children ... the effi- cacy of lamotrigine
treatment, including non ... side-effects of anti-epileptic drug treatments. ...

Outcomes of Add-on Treatment with Lamotrigine in Partial Epilepsy -
D Smith, G Baker, G Davies, M Dewey, DW Chadwick - Epilepsia, 1993 - Blackwell Synergy
... Because this trial was designed in part to develop new outcome measures for assessment
of treatment effects in chronic epilepsy, patients completed an HRQL ...

[BOOK] Handbook of Epilepsy Treatment -
SD Shorvon - 2000 - books.google.com
... Shorvon, SD (Simon D.) Handbook of epilepsy treatment/ Simon D.Shorvon. p.
cm Includes index. ... Page 10. 2 ? Handbook of Epilepsy Treatment ...

Selective amygdalohippocampectomy as a surgical treatment of mesiobasal limbic epilepsy. -
HG Wieser, MG Yasargil - Surg Neurol, 1982 - ncbi.nlm.nih.gov
Surg Neurol. 1982 Jun;17(6):445-57. Selective amygdalohippocampectomy as a surgical
treatment of mesiobasal limbic epilepsy. Wieser HG, Yasargil MG. ...

Source: Google Scholar

Early treatment stops epilepsy in its tracks

New Haven, Conn.—Yale School of Medicine researchers have shown for the first time that it is possible to suppress the development of epilepsy in genetically predisposed animals—which could open the door to treating epilepsy as a preventable disease.

According to the study published this month in Epilepsia, early treatment of epilepsy-prone rats with the anti-convulsant medication ethosuximide before the onset of seizures led to a marked suppression of seizures both later in life and months after treatment stopped.

“Current treatments for epilepsy may control seizures, but they do nothing to alter the underlying disease,” said Hal Blumenfeld, M.D., associate professor of neurology and lead author of the study. “These findings are important because they set the stage for prevention of epilepsy in genetically susceptible people.”

Epilepsy is a common neurological disorder that affects about 50 million people worldwide. It is characterized by seizures—temporary loss of consciousness or muscular control—that are precipitated by abnormal electrical overload on neurons within the brain.

Using a combination of molecular profiling, electroencephalogram (EEG) recordings, and power spectral analysis, Blumenfeld and his colleagues demonstrated that ethosuximide effectively blocked the expression of an epilepsy-associated maladaptive protein within neurons of the brain and reduced the number of seizures in treated animals.

“These findings prove that prevention of epilepsy in people is an achievable goal,” Blumenfeld said. “Strategies for primary prevention of diseases like epilepsy will be increasingly important as genetic prediction of these diseases improves.”

He said the results must be confirmed in other animals and with other medications before moving on to human treatment trials.

###

Epilepsia (doi:10.1111/j.1528-1167.2007.01458.x) (7 Dec 2007)

 
 
 
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