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Recent News and Articles on the Keywords: hematology + cell + stem  Related to the article below (Last Update: 8/5/2008)

Protein Key to Control Growth of Blood Cells
Earthtimes (press release), UK -
Tong's group and others previously found that Lnk is a negative regulator for HSCs, acting as a brake on stem cell expansion. In the current study, ...
Stem Cell Transplantation Research at The Cancer Center at ...
MarketWatch - Jul 23, 2008
... the scientific journal of the American Society of Hematology, that may take physicians one step closer to performing customized "designer" stem cell ...
Hospital?s Researchers Identify Stem Cell-Related Technology
NJBIZ, NJ - Jul 23, 2008
By Shankar P. Hackensack University Medical Center said today that work done by its researchers will help physicians perform customized "designer" stem cell ...

TopCancerNews.com
New clues into what causes mixed lineage leukemias and how might ...
TopCancerNews.com, TX - Jul 31, 2008
"We document early biological processes where human leukemia stem cells can be altered to form a particular type, or lineage, of leukemia by the factors ...
Vion Reports 2008 Second Quarter and Six-Month Results
Earthtimes (press release), UK -
... with temozolomide in brain tumors, and with stem cell transplantation in advanced hematologic malignancies, are also being conducted. ...VION
Maisonneuve-Rosemont Hospital receives highest certification in ...
Canada NewsWire (press release), Canada - Jul 10, 2008
"This accreditation gives patients the ultimate guarantee regarding quality of care and confirms our status as a world leader in hematopoietic stem cell ...

TopCancerNews.com
New Technology to increase the transplant efficiency of umbilical ...
TopCancerNews.com, TX - Jul 25, 2008
Kent W. Christopherson II, PhD, assistant professor of medicine and researcher in the Sections of Hematology and Stem Cell Transplantation at Rush, ...

Thanh Nien Daily
First leukemia patient cured with stem cells
VietNamNet Bridge, Vietnam - Jul 16, 2008
VietNamNet Bridge ? The Central Hematology and Blood Transfusion Hospital on July 15 announced its first successful treatment of leukemia with a stem cell ...
Vietnam performs first successful marrow transplant Xinhua
all 7 news articles »
Bio-Matrix Scientific Group, Inc. Announces Negotiations with Four ...
Business Wire (press release), CA - Jul 9, 2008
BMSN.us) is a biotechnology company that seeks to operate stem cell banking for the storage of adult stem cell and cord blood. ...OTC:BMSN
... Go to the Article
CancerWise - Aug 1, 2008
The hope is that this combination could be added with little additional toxicity as an adjunct to other therapies, such as stem cell transplant or high-dose ...
Source: Google News

… of Metastatic Renal-Cell Carcinoma after Nonmyeloablative Allogeneic Peripheral-Blood Stem-Cell … -
R Childs, A Chernoff, N Contentin, E Bahceci, D … - New England Journal of Medicine, 2000 - content.nejm.org
... Conclusions Nonmyeloablative allogeneic stem-cell transplantation can induce ... of
metastatic renal-cell carcinoma in ... From the Hematology Branch, National Heart ...

… IN PATIENTS WITH MULTIPLE MYELOMA TREATED BY HIGH-DOSE THERAPY AND HAEMOPOIETIC STEM CELL … -
J BladE, D Samson, D Reece, J Apperley, B … - British Journal of Haematology, 1998 - Blackwell Synergy
... AND PROGRESSION IN PATIENTS WITH MULTIPLE MYELOMA TREATED BY HIGH-DOSE THERAPY AND
HAEMOPOIETIC STEM CELL TRANSPLANTATION British Journal of Haematology 102 (5 ...

… in Immunocompromised Patients with Cancer and Hematopoietic Stem Cell Transplants: An International … -
S Ascioglu, JH Rex, B de Pauw, JE Bennett, J Bille … - Clinical Infectious Diseases, 2002 - UChicago Press
... cancer patients receiving conventional chemotherapy or autologous stem cell transplants. ...
European Journal Of Haematology 78:6, 532. Costanza Bruno, Salvatore ...

… and the effects on peripheral blood CD34+ cell counts and on the collection of peripheral blood stem … -
DF Stroncek, ME Clay, ML Petzoldt, J Smith, W … - Transfusion, 1996 - Blackwell Synergy
... William I. Bensinger Rainer Storb. (2001) ALLOGENEIC PERIPHERAL BLOOD STEM CELL
TRANSPLANTATION. Reviews in Clinical and Experimental Hematology 5:2, 67?86 ...

Epidemiology and Outcome of Mould Infections in Hematopoietic Stem Cell Transplant Recipients -
KA Marr, RA Carter, F Crippa, A Wald, L Corey - Clinical Infectious Diseases, 2002 - UChicago Press
... Hematopoietic stem cell transplantation (HSCT) for advanced myelodysplastic syndrome
(MDS) after ... Meeting of the American Society of Hematology (San Francisco). ...

Placental Blood as a Source of Hematopoietic Stem Cells for Transplantation Into Unrelated … -
J Kurtzberg, M Laughlin, ML Graham, C Smith, JF … - Obstetrical & Gynecological Survey, 1997 - obgynsurvey.com
... Oral Contraceptives: A Cause of Hyperbilirubinemia in Stem Cell Transplant
Patients. Journal of Pediatric Hematology/Oncology. 21 ...

In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell … -
PD Kottaridis, DW Milligan, R Chopra, RK … - Blood, 2000 - bloodjournal.hematologylibrary.org
... 2000;96:2419-2425) ? 2000 by The American Society of Hematology. Introduction. ...
High-dose chemoradiotherapy followed by allogeneic stem cell transplantation (SCT ...

… transplantation-related mortality following unrelated donor stem cell transplantation by using a … -
R Chakraverty, K Peggs, R Chopra, DW Milligan, PD … - Blood, 2002 - bloodjournal.hematologylibrary.org
... 2002;99:1071-1078) ? 2002 by The American Society of Hematology. Introduction. ... Unrelated
donor stem cell transplantation (SCT) using standard myeloablative ...

… survival and response after high-dose therapy and autologous stem cell transplantation in systemic … -
P Moreau, V Leblond, P Bourquelot, T Facon, A … - British Journal of Haematology, 1998 - Blackwell Synergy
... AL amyloidosis: association with dominant amyloid-related organ involvement and
survival after stem cell transplantation. British Journal of Haematology 106:3 ...

High-Dose Therapy and Autologous Peripheral Blood Stem Cell Transplantation in Multiple Myeloma: Up- … -
JP Fermand, P Ravaud, S Chevret, M Divine, V … - Blood, 1998 - bloodjournal.hematologylibrary.org
... and the Haematology Unit, Centre Hospitalier, Caen, France. ... Results to date indicate
that high-dose therapy (HDT) with autologous stem cell support improves ...

Source: Google Scholar

Adult stem cell heart attack study updated at American Society for Hematology Meeting

Doctors are using patients' own bone marrow stem cells (progenitor cells) to treat the damage to cardiac muscle after a heart attack in a study at Emory University School of Medicine.

The study investigators--Emory cardiologist Arshed Quyyumi, MD, and hematologist/oncologist Edmund Waller, MD--will update their colleagues on its progress at the American Society of Hematology meeting in Atlanta next week.

"This is one of the first trials where patients receive varying doses of a cell population that is enriched for progenitor cells," says Dr. Waller, director of Emory's Bone Marrow and Stem Cell Transplant Center in the Emory Winship Cancer Institute.

Several groups of researchers around the world have reported clinical trials in which stem cells are used to try to restore the heart's pumping power, with mixed results.

Dr. Waller says his team plans to present information on the safety and feasibility of harvesting the bone marrow cells and the migration of stem cells in response to SDF-1, a signaling molecule released by damaged tissue that is believed to help guide the stem cells to sites where tissue repair is needed.

The clinical trial, which began in July 2006, has progressed halfway through the four planned groups of patients (40 total) who receive different amounts of sorted cells.

The magnetic sorting process, performed by Progenitor Cell Therapeutics, enriches for progenitor cells that doctors believe are able to help repair cardiac muscle.

In the clinical trial, patients receive the standard of care for their condition, including cardiac catheterization, angioplasty and implantation of a stent in the blocked artery. During catheterization, the bone marrow cells are introduced into the coronary artery where a blockage caused the patient's heart attack. To guide the bone marrow cells to the critical area, a balloon is inflated around the catheter, temporarily sealing off the artery from the rest of the circulation.

The patients are followed closely for the first year and then at regular intervals over a five-year period.

###

The study is funded by biotech company Amorcyte. Drs. Waller and Quyumi are paid consultants to Amorycyte.

A magazine article about the study is available at:
http://whsc.emory.edu/_pubs/em/2007summer/heal_thyself.html

A related poster session is scheduled for Dec. 8 at 5:30 p.m.

More information about the American Society of Hematology meeting is available at
http://www.hematology.org/meetings/2007/index.cfm.
 
 
 
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