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Recent News and Articles on the Keywords: halt + disease + web  Related to the article below (Last Update: 8/5/2008)


Chatter Shmatter
Experimental Alzheimer?s Drug Rember Reduces Disease Symptoms
Chatter Shmatter, Canada - Jul 29, 2008
?We?ve demonstrated for the first time we can halt the disease by a treatment that aims to dissolve the tangles,? said Claude Wischik of the University of ...
VIRxSYS to Host a Web Conference to Announce Clinical Trial Update
MarketWatch - Jul 21, 2008
Activation of both cellular and humoral immunity can also halt the slow destruction of the immune system by the latently dormant virus. ...
Presidential candidate Nader promotes single-payer health care plan
News-Medical.net, Australia - Aug 3, 2008
The editorial recommends that a "simple government-run plan that provides the basics and lets people buy private coverage for the extras" would halt the ...
10-year battle with pain highlights Lyme disease debate
CNN - Jul 6, 2008
The society's purpose, according to its Web site, is to improve health care in areas related to such diseases. In particular, the documentary takes aim at ...
By Johnny Neihu 強尼內湖
Taipei Times, Taiwan - Aug 1, 2008
The following year he tried to introduce a five-year nationwide sex ban in an attempt to halt the spread of the disease. Unfortunately, Mswati had trouble ...
OTCPicks.com: OTCPicks.com Daily Market Movers Digest Midday ...
Trading Markets (press release), CA - Jul 31, 2008
It offers drugs for neurological diseases associated with aging, such as Alzheimer's disease, as well as psychiatric disorders, such as schizophrenia, ...PINK:MGRN - OIIM - MEMY
NIAID will not move forward with the PAVE 100 HIV Vaccine Trial
EurekAlert (press release), DC - Jul 17, 2008
The study was to begin US recruitment in October 2007 but was postponed last fall following the decision to halt immunizations in the STEP HIV vaccine study ...

Annapolis Capital
All star lacrosse game to raise awareness of cancers
Annapolis Capital, MD - Jul 29, 2008
The first big event for Millerstrong is to celebrate lacrosse and the survivors of testicular cancer, but also to celebrate the lives lost to the disease. ...
Prevailing theory of aging challenged in Stanford worm study
PressZoom (press release), Netherlands - Jul 29, 2008
Their discovery contradicts the prevailing theory that aging is a buildup of tissue damage akin to rust, and implies science might eventually halt or even ...
Infectious disease expert to speak Thursday
Steamboat Pilot, CO - Jul 8, 2008
The global economy would come to a halt, and since we could not expect appropriate vaccines to be available for many months and we have very limited ...
Source: Google News

Fabry Disease, an Under-Recognized Multisystemic Disorder: Expert Recommendations for Diagnosis, … -
RJ Desnick, R Brady, J Barranger, AJ Collins, DP … - Annals of Internal Medicine, 2003 - annals.highwire.org
... For older patients with more advanced disease, the goal is to both halt disease
progression and reverse ... Lysosomal Storage Disease Network Web site: http ...

Neuroprotective agents for clinical trials in Parkinson's disease A systematic assessment -
BM Ravina, SC Fagan, RG Hart, CA Hovinga, DD … - Neurology, 2003 - AAN Enterprises
... article can be found on the Neurology Web site ... Interventions that can slow or halt
the progression of PD ... with the primary aim of slowing disease progression in ...

Clinical Factors Associated With Progression of Glaucomatous Optic Disc Damage in Treated Patients -
G Tezel, KD Siegmund, K Trinkaus, MB Wax, MA Kass, … - Archives of Ophthalmology, 2001 - Am Med Assoc
... message because your Web browser does not support basic Web standards. ... CURRENT
therapeutic management of glaucoma aims to halt disease progression by reducing ...

NEWS: Is Apoptosis Key in Alzheimer's Disease? -
M Barinaga - Science, 1998 - sciencemag.org
... are using a browser that does not support current Web standards. ... neuroscientists
doubt that blocking it will slow or halt the progress of the disease. ...

… in a pre-symptomatic neonate with late infantile metachromatic leukodystrophy does not halt disease … -
RG Bredius, LA Laan, AC Lankester, BJ Poorthuis, … - Bone Marrow Transplant, 2007 - nature.com
... Full text access provided to Googlebot Access by Web Services. ... neonate with late
infantile metachromatic leukodystrophy does not halt disease progression. ...

Young Women With Chronic Disease: A Female Perspective on the Impact and Management of Rheumatoid … -
MJ HARRISON - Arthritis & Rheumatism (Arthritis Care & Research), 2003 - doi.wiley.com
... Web site at www.aarda.org. ... Although these findings suggest that the window of
opportunity to halt disease progression may be wider in women, guide- lines have ...

FOOT-AND-MOUTH DISEASE: UK Outbreak Is Latest in Global Epidemic -
J Pickrell, M Enserink - Science, 2001 - sciencemag.org
... ISI Web of Science (7). ... Thousands of animals have been slaughtered and burned
atop huge pyres in a bid to halt the disease's spread. ...

[PDF] Couples Cull Embryos to Halt Heritage of Cancer -
AMY HARMON - DNA, 2006 - demog.berkeley.edu
... of the disease. Page 3 of 10 Couples Cull Embryos to Halt Heritage of Cancer - New
York Times 9/3/2006 http://www.nytimes.com/2006/09/03/health/03gene.web.html ...

NEW PERSPECTIVES FOR PRION THERAPEUTICS MEETING: Prion Disease Treatment's Early Promise Unravels -
P Follette - Science, 2003 - sciencemag.org
... that you are using a browser that does not support current Web standards. ... shows modest,
early success in some patients but fails to halt the disease. ...

Selegiline use to prevent progression of Parkinson's disease. Experience in 22 de novo patients -
TS Elizan, MD Yahr, DA Moros, MR Mendoza, S Pang, … - Archives of Neurology, 1989 - Am Med Assoc
... your Web browser does not support basic Web standards. ... of B-type monoamine oxidase,
can halt the natural progression of Parkinson's disease, its use in ...

Source: Google Scholar

National Institutes of Health Award to Help Halt Disease Spread by Ticks

Roman Ganta, a professor of diagnostic medicine and pathobiology at Kansas State University, has been awarded a grant of $1,825,000 by the National Institutes of Health to figure out how to stop the tick-borne bacteria, Ehrlichia chaffeensis, from making animals and people sick.

This is the second grant of roughly the same size Ganta has received for this research.

Ehrlichia chaffeensis affects people and animals primarily in the southeastern and south central regions of the U.S. It is transmitted by the lone star tick. The resulting sickness, termed Ehrlichiosis, is hard to diagnose because its symptoms' similarities with other, more minor infections. Symptoms include headache, fever, malaise and muscle aches. For those with compromised immune systems, the bacterial infection could be fatal.

Though very few cases are reported -- around 1,500 since the Centers for Disease Control deemed it a disease of concern in the late 1980s -- Ganta estimates that as many as 50,000 people have actually contracted ehrlichia chaffeensis. Though relative to the nation's population that doesn't seem significant, the ensuing infection and symptoms can be serious, especially if untreated. As many as half of the patients diagnosed with ehrlichiosis require hospitalization.

This particular tick-borne pathogen is also unique because it circumvents the initial defenses of the immune system of the animal or human the tick bites, according to Ganta.

When bacteria enters the mammalian body the response is typically the same: the bacteria multiply and the immune system gears up, sending out its own organisms -- cells derived from white blood cells called macrophages -- to seek out and destroy the offender.

The average, healthy immune system can clear the body of most bacterial infections. But ehrlichia chaffeensis gets past that first line of defense, making the infection persist and the subsequent illness difficult to get rid of.

"It's like the enemy entering into a battlefield and knowing exactly where the landmines are and diffusing them all," Ganta said.

Over the last five years, Ganta's research team has been working under a prior federal grant, also from the National Institutes of Health, to uncover exactly how the bacteria works. They recreated the bacteria using cells from mice and from ticks. The current study revealed that the tick cells are what made the difference, and that the tick's ecology changes the bacteria by adding proteins, enabling bacteria to slip by the immune system.

"Understanding the molecular basis for persistence by these bacteria has been critical in developing effective methods to control this and other tick-borne pathogens," Ganta said. "Our research is focused on understanding the pathogen evasion mechanisms, and then using those to defeat it."

The trick now is to learn how to turn those proteins off, leaving the bacteria vulnerable, Ganta said. That's the research his new grant will fund.

Ganta said that tick-borne pathogens like ehrlichia chaffeensis have long been recognized as a persistent concern for the health of several companion animals and livestock. The number of cases in humans has also risen in recent years, increasing the threat to public health.

The hope is that once Ganta comes up with a way to fight off the bacteria, that will pave the way for solutions to other forms of ehrlichia, some of which are devastating for cattle and other food animals.

The $1,825,000 grant is for five years of study at $365,000 a year.
 
 
 
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