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Recent News and Articles on the Keywords: risk + osteoporosis + test  Related to the article below (Last Update: 8/5/2008)

UA study: Woman's bone density may predict breast cancer risk
Tucson Citizen, AZ -
While the two scores were rated independent of each other, Chen found that those who rated as being high risk on both the bone density test and the Gail ...
Is the new test for osteoporosis better than a bone density test?
Boston Globe, United States - Jul 28, 2008
But the FRAX doesn't go far enough in presenting risk in a way that patients can understand, said Dr. Bruce Ettinger, a long-time osteoporosis researcher ...
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A different way to test bone density
Dallas Morning News, TX - Jul 29, 2008
An ultrasound exam of the heel may be able to predict if a woman is at heightened risk for fractures due to osteoporosis, according to a new multicenter ...
Some doctors skeptical of mobile health screenings
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He did, however, see merit to screening for bone density, which is done to determine osteoporosis risk. Guidelines from the American Heart ...

Los Angeles Times
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... with side effects that include incontinence, impotence, weight gain, hot flashes and osteoporosis. The test also debunks a high rate of false positives, ...
Panel Urges End to Prostate Screening at Age 75 New York Times
Panel advises men over 75 to avoid prostate cancer screening Contra Costa Times
all 546 news articles »
Skin Patch Test Could Predict Risk For Inflammatory Illnesses
eMaxHealth.com, NC - Jul 31, 2008
... an easier alternative to a blood test for predicting risk for inflammatory disorders, such as metabolic syndrome, cardiovascular disease, osteoporosis, ...
Drug Test a Success for Amgen
New York Times, United States - Jul 26, 2008
... into a strong reduction in the risk of fractures, which the Food and Drug Administration regards as the most relevant measure of an osteoporosis drug. ...AMGN

Daily Mail
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This can lead to problems such as osteoporosis, while Paget's disease causes the cells that make new bone to work too quickly, throwing down new cells even ...

The News - International
Detoxify your body
The News - International, Pakistan - Jul 29, 2008
In addition if you have risk factors for osteoporosis ask your doctor if you need a bone density test and whether you should change your diet or exercise ...
Source: Google News

… Low Bone Mineral Density in Postmenopausal Women Results From the National Osteoporosis Risk -
ES Siris, PD Miller, E Barrett-Connor, KG Faulkner … - JAMA, 2001 - Am Med Assoc
... on results of peripheral BMD testing for management decisions. Early identification
of women at increased risk of fracture because of osteoporosis presents an ...

Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of … -
SM Cadarette, SB Jaglal, N Kreiger, WJ McIsaac, GA … - Canadian Medical Association Journal, 2000 - Can Med Assoc
... JI Halse, and TK Kvien Clinical decision rules in rheumatoid arthritis: do they
identify patients at high risk for osteoporosis? Testing clinical criteria in a ...

… of Strontium Ranelate on the Risk of Vertebral Fracture in Women With Postmenopausal Osteoporosis. -
PJ Meunier, C Roux, E Seeman, S Ortolani, JE … - Obstetrical & Gynecological Survey, 2004 - obgynsurvey.com
... Be- cause it is not possible to identify high-risk TABLE 1 Positive and negative
test results for the detection of Chlamydia trachomatis by specimen source and ...

… White Women With Peripheral Bone Densitometry: Evidence From the National Osteoporosis Risk -
PD MILLER, ES SIRIS, E BARRETT-CONNOR, KG FAULKNER … - Journal of Bone and Mineral Research, 2002 - Am Soc Bone Min Res
... white women, without prior diagnosis of osteoporosis. At enrollment, each participant
completed a risk assessment questionnaire and had BMD testing at the heel ...

… of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene … -
B Ettinger, DM Black, BH Mitlak, RK Knickerbocker, … - JAMA, 1999 - Am Med Assoc
... greater than 90% power (2-tailed t test, P<.05 ... tamoxifen, suggested a decrease in
the risk of clinical ... in early postmenopausal women without osteoporosis, 1 we ...

Diagnosis of osteoporosis and assessment of fracture risk -
JA Kanis - The Lancet, 2002 - Elsevier
... is no universally accepted policy for screening to identify individuals at high
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Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: … -
JA Kanis, JA Kanis - Osteoporosis International, 1994 - Springer
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Fracture Risk Reduction with Alendronate in Women with Osteoporosis: The Fracture Intervention Trial -
DM Black, DE Thompson, DC Bauer, K Ensrud, T … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc
... analyses were conducted using definitions of osteoporosis based on ... in the RR, we
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Yield of Laboratory Testing to Identify Secondary Contributors to Osteoporosis in Otherwise Healthy … -
C Tannenbaum, J Clark, K Schwartzman, S … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
... Among patients with major risk factors for bone ... evidence-based guidelines for laboratory
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Development and assessment of the Osteoporosis Index of Risk (OSIRIS) to facilitate selection of … -
WB Sedrine, T Chevallier, B Zegels, A Kvasz, MC … - Gynecological Endocrinology, 2002 - ingentaconnect.com
... the model, residual analysis was per- formed to test for normality ... in the final linear
model were used to develop the Osteoporosis Index of Risk for the ...

Source: Google Scholar

Simple test predicts osteoporosis risk in men

Last Updated: 2007-12-06 12:02:52 -0400 (Reuters Health)

NEW YORK (Reuters Health) - A simple test, called the Male Osteoporosis Risk Estimation Score (MORES), identifies men at risk for osteoporosis who might benefit from dual-energy X-ray absorptiometry (DXA) to determine their bone mineral density, according to a report in the Annals of Family Medicine.

The test can also identify men with osteopenia -- below normal bone mineral density that has not yet progressed to osteoporosis - which would give patients the opportunity to modify their lifestyle and diet to prevent progression to osteoporosis, Dr. Angela J. Shepherd from The University of Texas Medical Branch, Galveston, told Reuters Health.

In the next 25 to 50 years, osteoporosis and the fractures that will result will be a major world health issue unless it is appropriately addressed, Shepherd said. "From Europe to China, many experts are wrestling with how to best decide which men are at risk for osteoporosis and should be tested with DXA."

Shepherd and associates used data from the National Health and Nutrition Examination Survey (NHANES) III to develop and validate a test that could be used by health professionals to identify men at increased risk for osteoporosis and fractures, and would therefore benefit from DXA testing.

The final predictive model contained only three variables: age (3 categories), weight (3 categories), and history of chronic obstructive pulmonary disease (COPD) (yes or no).

A score of 6 points or more, out of a maximum of 13 points, had a sensitivity of 93 percent and a specificity of 59 percent, which means that most of the "true positives" - those who actually had osteoporosis - were identified and more than half of the "true negatives" - those who did not have osteoporosis -- were correctly identified.

MORES yielded similar sensitivity and specificity across non-Hispanic white, non-Hispanic black, and Hispanic racial/ethnic groups, although the specificity was slightly higher in non-Hispanic whites.

The researchers estimate that using MORES in men 50 years of age or older, the number needed to screen to prevent one hip fracture in the next 10 years was 279.

We plan a clinical study that will involve up to 3000 men 60 years of age or older who attend our primary care clinics, Shepherd added. "If the MORES is validated in this clinical setting, we will repeat a similar study on a larger, multicentered scale."

"Ultimately," she concluded, "I hope that our future research will add to the limited but growing knowledge of osteoporosis in men and encourage health policy makers to undertake the arduous task of trying to figure out if there are men who should be considered for bone density testing (or whatever other measures needed) so we can ultimately prevent hip fractures."

SOURCE: Annals of Family Medicine, November/December 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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