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Recent News and Articles on the Keywords: cancer + breast + risk  Related to the article below (Last Update: 8/5/2008)


BBC News
How MRI Scans Find Breast Cancers Like Christina Applegate's
U.S. News & World Report, DC -
For this reason, the test is recommended only for those at increased risk of breast cancer. (Breast cancer is very uncommon in those under 50, ...
AssociatedPress
HealthWatch: Applegate's Cancer Serves As Reminder WCBS-TV New York
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Food Consumer - FOX 9 News
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Breast cancer: What you need to know
Food Consumer, IL -
Both the shortened menstrual circle and lowered estradiol may indicate lower risk for hormone-sensitive breast cancer. Seaweed may reduce breast cancer risk ...

Los Angeles Times
Health Buzz: Prostate Cancer Screening and Other Health News
U.S. News & World Report, DC -
For this reason, the test is recommended only for those at increased risk of breast cancer. Last year, Katherine Hobson explained that women at high risk of ...
Will Older Men Give Up the PSA Test? New York Times
all 546 news articles »
UA study: Woman's bone density may predict breast cancer risk
Tucson Citizen, AZ -
The Gail score is an commonly used breast cancer risk assessment tool that looks at a woman's race, family history of breast cancer, onset of menstrual ...

Canada.com
Genetic discovery may lead to blood test for families with high ...
The Canadian Press, TORONTO -
Her mother died of breast cancer at 35 when she was six, following the death of her mother's twin sister from the same malignancy. ...
Genetic discovery offers hope to family with legacy of cancer Canada.com
Genetic discovery may lead to new blood test for people at high ... Canada NewsWire (press release)
HOSPITAL FOR SICK CHILDREN Canada NewsWire (press release)
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Low radiation exposure tied to cancer risk
The Daily Yomiuri, Japan -
However, the women's risk of suffering uterine cancer and breast cancer were 1.76 times and 1.24 to 1.47 times higher, respectively. ...
Early screening is crucial to improving recovery rates for breast ...
Orlando Sentinel, FL -
"As you age, your risk of developing breast cancer increases," says Dr. Nikita Shah, director of the breast-cancer unit at MD Anderson Cancer Center Orlando ...
Craig W. Philips Takes Helm at CTI
FOXBusiness -
Anthracyclines have been shown to be very active clinically in a number of tumor types, such as lymphoma, leukemia, and breast cancer. ...CTIC - OTC:CMTX
Does aluminum cause Alzheimer's or breast cancer?
Bradenton Herald,  United States -
By JOE GRAEDON I have heard about a link between aluminum in antiperspirants and breast cancer. I have also read that aluminum may be associated with ...
Personal Health Sorting Out Coffee?s Contradictions
New York Times, United States -
Cancer. Panic swept this coffee-dependent nation in 1981 when a Harvard study tied the drink to a higher risk of pancreatic cancer. ...
Source: Google News

… for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project … -
B Fisher - J Natl Cancer I, 1998 - jnci.oxfordjournals.org
... [Abstract] [Full Text] [PDF], Home page, JNCI J Natl Cancer Inst Home page ML Bondy
and LA Newman Assessing breast cancer risk: evolution of the gail model. ...

The effect of raloxifene on risk of breast cancer in postmenopausal women -
SR Cummings, S Eckert, KA Krueger, D Grady, TJ … - feedback, 2005 - biomedcentral.com
... Paper Report. The effect of raloxifene on risk of breast cancer in postmenopausal
women SR Cummings, S Eckert, KA Krueger, D Grady, TJ Powles, JA Cauley, L ...

Risk factors for breast cancer in women with proliferative breast disease. -
WD Dupont, DL Page - N Engl J Med, 1985 - ncbi.nlm.nih.gov
... Although cysts alone did not substantially elevate the risk, women with both cysts
and a family history of breast cancer had a risk 2.7 times higher than that ...

The use of Estrogens and Progestins and the Risk of Breast Cancer in Postmenopausal Women. -
GA Colditz, SE Hankinson, DJ Hunter, WC Willet, … - Obstetrical & Gynecological Survey, 1995 - obgynsurvey.com
... To quantify the relation between hormone use and breast cancer risk in postmenopausal
women, the authors extended the follow-up of the participants in the ...

Genetic analysis of breast cancer in the cancer and steroid hormone study. -
EB Claus, N Risch, WD Thompson - American Journal of Human Genetics, 1991 - pubmedcentral.nih.gov
... Abstract. The familial risk of breast cancer is investigated in a large
population-based, case-control study conducted by the Centers for Disease Control. ...

Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer Risk -
C Schairer, J Lubin, R Troisi, S Sturgeon, L … - JAMA, 2000 - Am Med Assoc
... Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer
Risk Catherine Schairer, PhD ; Jay Lubin, PhD ; Rebecca ...

Migration Patterns and Breast Cancer Risk in Asian-American Women -
RG Ziegler, RN Hoover, MC Pike, A Hildesheim, AMY … - jnci, 1993 - jnci.oxfordjournals.org
... Migration Patterns and Breast Cancer Risk in Asian-American Women. ... Results: A sixfold
gradient in breast cancer risk by migration patterns was observed. ...

[PDF] Circulating concentrations of insulin-like growth factor-I and risk of breast cancer -
SE Hankinson, WC Willett, GA Colditz, DJ Hunter, … - Lancet, 1998 - mcgill.ca
... concentrations was highly associated with breast-cancer risk and so this ratio was
also assessed. ... Evidence of prenatal influences on breast cancer risk. ...
-

Blood Levels of Organochlorine Residues and Risk of Breast Cancer -
MS Wolff, PG Toniolo, EW Lee, M Rivera, N Dubin - jnci, 1993 - jnci.oxfordjournals.org
... whether exposure to PCBs and to DDE [1,1-dichloro-2,2-bis(p-chlorophenyl) ethylene],
the major metabolite of DDT, is associated with breast cancer risk in women ...

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. -
DF Easton, D Ford, DT Bishop - American Journal of Human Genetics, 1995 - pubmedcentral.nih.gov
... Under the assumption of no heterogeneity of risk between families, BRCA1 is estimated
to confer a breast cancer risk of 54% by age 60 years (95% confidence ...

Source: Google Scholar

Widely used chemical may raise breast cancer risk

Last Updated: 2007-12-06 10:30:21 -0400 (Reuters Health)

By Anthony J. Brown, MD

NEW YORK (Reuters Health) - The results of an animal study suggest that infants exposed to BBP, a chemical additive used in pipes, vinyl floor tiles, carpet-backing, and other household items, may affect mammary gland development and perhaps increase the susceptibility to breast cancer. BBP (n-butyl benzyl phthalate) is a "plasticizer," which is added to substances such as cement, concrete and clay to increase fluidity.

This study is the first "demonstrating that exposure to this compound soon after birth results in alterations in the expression of genes present in the mammary gland," senior author Dr. Jose Russo, from Fox Chase Cancer Center in Philadelphia, told Reuters Health.

"Our findings are unique in the sense that we are studying the lifetime effect of BBP on the mammary gland, long before it starts developing under the influence of the hormones of puberty," he added. Russo's group originally observed genetic changes induced by BBP that occur very early in life, which may "result in significant modifications in the risk of the mammary gland to develop cancer later on in life."

As reported in the online issue of BMC Genomics, the researchers fed BBP to lactating rats, and their offspring absorbed the chemical in breast milk. According to the report, the amount of BBP ingested by the offspring was roughly equivalent to the safe dose limit for humans established by the Environmental Protection Agency.

BBP exposure increased the uterine and body weight ratio in female offspring and decreased the body weight.

Although exposure to the chemical did not affect the appearance of the mammary gland, it did increase the proliferation of cells in lobules and other breast tissue compartments. Genetic analysis revealed that BBP exposure also increased the expression of several genes related to cell proliferation and differentiation, communication, and signal transduction.

Many of these effects seemed to disappear after BBP exposure was removed; however, the subtle genetic changes may have a lasting effect, the report indicates.

"The take-home message is that for preventing breast cancer in adulthood it is necessary to protect both the newborn child and the mother from exposure." BBP has an effect on estrogen and may disrupt hormone production, Russo emphasized.

His group is currently conducting studies to evaluate the influence of these early changes in gene expression induced by BBP and the response of breast tissue to exposure to chemical carcinogens later in life, he added.

SOURCE: BMC Genomics, December 5, 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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