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Recent News and Articles on the Keywords: anaphylaxis + epinephrine + 253,000  Related to the article below (Last Update: 8/5/2008)

Be wary of Henna tattoos
Belleville News Democrat,  USA -
... dose of epinephrine -- the drug of choice for treating severe allergic reactions -- was needed in nearly one in five cases of food-induced anaphylaxis ...
Severe allergic reaction may need more epinephrine
Reuters - Jul 9, 2008
Common causes of anaphylaxis are foods, drugs or insect bites. The treatment, which should be given as soon as possible, is an epinephrine injection. ...
Ask The Mayo Clinic: What to do about allergic reactions
Seattle Post Intelligencer - Jul 20, 2008
The epinephrine should be given right away at home, in the field or in the emergency room. Those who have had an anaphylactic episode should carry an ...
Half of kids with peanut allergy don't have Epi-Pen
Reuters UK, UK - Jul 15, 2008
Studies have shown that the main factor in whether an anaphylactic reaction is fatal is whether or not the person was carrying an epinephrine self-injector ...
Survey to look at how many Canadians have potentially fatal food ...
The Canadian Press, TORONTO - Jul 23, 2008
Anaphylaxis Canada, which has also contributed funding toward the $400000-$500000 study, estimates that four per cent of Canadians are at risk for an ...
Biphasic anaphylactic reaction to blue dye during sentinel lymph ...
7thSpace Interactive (press release), NY - Jul 27, 2008
The late phase was initially refractory to epinephrine. Conclusions: Early recognition, aggressive hemodynamic management, and prolonged monitoring are ...

insideTORONTO.com
Constant vigilance necessary to survive severe food allergies
insideTORONTO.com, Canada - Jul 28, 2008
Anaphylaxis is a medical term that means "a life-threatening reaction" and represents the most severe type of allergy, said Beatrice Povolo, ...
Hear that buzzing? Learn about anaphylaxis before it's too late
Belleville News Democrat,  USA - Jul 21, 2008
If available, administer self-injectable epinephrine (eg, EpiPen, TwinJect), which should be carried by all persons at risk for anaphylaxis. ...

Canada.com
Health Canada warns of faulty emergency injector for allergies
Canada.com, Canada - Jul 14, 2008
The injectors are meant to kick-start stricken people's hearts with epinephrine, also known as adrenalin, if they are going into anaphylactic shock, ...
Kids with asthma and allergies might need multiple EpiPens
ABC7Chicago.com,  USA - Jul 9, 2008
The EpiPen is an injection that delivers a medication called epinephrine. It's used to top anaphylaxis a severe allergic reaction that develops quickly. ...
Source: Google News

Anaphylaxis: Epinephrine & Emergency Responses.
JD Grabenstein, MS Pharm - Hospital Pharmacy, 1997 - pt.wkhealth.com
... October 1997, 32:10 > Anaphylaxis: Epinephrine & Emergency... ... Anaphylaxis: Epinephrine
& Emergency Responses. [Features And Columns: Immunologic Pharmacopeia]. ...

Epinephrine absorption in children with a history of anaphylaxis. -
FE Simons, JR Roberts, X Gu, KJ Simons - J Allergy Clin Immunol, 1998 - ncbi.nlm.nih.gov
... Winnipeg, Canada. BACKGROUND: Prompt injection of epinephrine is the
cornerstone of systemic anaphylaxis treatment. The rate of ...

… for an out-of-hospital population: A novel approach to studying the epidemiology of anaphylaxis -
FER Simons, S Peterson, CD Black - The Journal of Allergy and Clinical Immunology, 2002 - Elsevier
... It is possible that the occurrence rate of anaphylaxis ascertained indirectly from
epinephrine dispensing data might have been overestimated in the present ...

First-aid treatment of anaphylaxis to food: Focus on epinephrine -
FER Simons - The Journal of Allergy and Clinical Immunology, 2004 - Elsevier
... The cornerstone of first-aid treatment of anaphylaxis is epinephrine injected
intramuscularly in the vastus lateralis muscle (lateral aspect of the thigh). ...

… anaphylaxis management in children who were prescribed an epinephrine autoinjector device (EpiPen) -
MS Gold, R Sainsbury - The Journal of Allergy and Clinical Immunology, 2000 - Elsevier
... 7-9 For this reason it is advo- cated that parents and other caregivers of children
with anaphylaxis are supplied with epinephrine for first aid use. ...

Anaphylaxis and epinephrine auto-injector training: who will teach the teachers? -
M Grouhi, M Alshehri, D Hummel, CM Roifman - J Allergy Clin Immunol, 1999 - ncbi.nlm.nih.gov
Click here to read Anaphylaxis and epinephrine auto-injector training: who will
teach the teachers? Grouhi M, Alshehri M, Hummel D, Roifman CM. ...

Adrenaline in the treatment of anaphylaxis: what is the evidence? -
APC McLean-Tooke? - BMJ, 2003 - pubmedcentral.nih.gov
... Top. Methods. We searched Medline using the key words adrenaline, anaphylaxis,
epinephrine, and Epipen, and articles from the authors' personal collection. ...

Anaphylaxis in Children: Clinical and Allergologic Features -
E Novembre, A Cianferoni, R Bernardini, L Mugnaini … - Pediatrics, 1998 - Am Acad Pediatrics
... use in the treatment of anaphylaxis should be promoted, because in only 17 out of
the 95 episodes of anaphylaxis was epinephrine actually administered. ...

… Inhalations Be Substituted for Epinephrine Injection in Children at Risk for Systemic Anaphylaxis? -
FER Simons, X Gu, LM Johnston, KJ Simons - Pediatrics, 2000 - Am Acad Pediatrics
... 359-362 [Abstract/Free Full Text]; Grouhi M, Alshehri M, Hummel D, Roifman CM
Anaphylaxis and epinephrine auto-injector training: who will teach the teachers? ...

Epinephrine for the out-of-hospital (first-aid) treatment of anaphylaxis in infants: Is the ampule/ … -
FER Simons, ES Chan, X Gu, KJ Simons - The Journal of Allergy and Clinical Immunology, 2001 - Elsevier
... A retrospective study of epinephrine administration for anaphylaxis: how many doses
are needed? Allergy Asthma Proc 1999;20:383-6. 19. Pumphrey RSH. ...

Source: Google Scholar

Two epinephrine doses may be needed for anaphylaxis

Last Updated: 2007-12-05 14:18:44 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Some patients who are at risk for a severe allergic reaction caused by a food allergy will require two doses of epinephrine, rather than just one, according to the findings of a new study. Researchers therefore recommend that allergic patients carry two doses of epinephrine.

Dr. Eyal Oren of Massachusetts General Hospital in Boston and colleagues reviewed the records of patients seen at the hospital's emergency department for food-induced anaphylaxis, a severe, life-threatening allergic reaction that requires immediate treatment. It is characterized by swelling of the airways that can block breathing and may also include a dramatic drop in blood pressure.

The investigators reviewed medical records of 39 patients who sought treatment for severe allergic reactions to food at the hospital's emergency department over the course of 1 year. Nineteen had anaphylaxis.

Twelve of the patients were given at least one dose of epinephrine, while three, or 16 percent, received two doses. The patients given two doses were allergic to peanuts or tree nuts, and two of the three experienced a drop in blood pressure.

"These results suggest that the use of multiple doses of epinephrine in the management of food-induced anaphylaxis is not a rare occurrence," they write in the current issue of the Annals of Allergy, Asthma and Immunology.

Recent recommendations have called for allergic individuals to carry two doses of epinephrine rather than just one. These findings suggest that those with food allergies will also benefit from doing so, Oren and his team note.

Given the small size of the study and the fact that patients who were not seen in the emergency room for treatment weren't included, more research is needed to confirm the findings, the researchers say.

Nevertheless, they conclude, the findings suggest that patients "at risk for food-induced anaphylaxis should carry at least two doses of self-injectable epinephrine."

SOURCE: Annals of Allergy, Asthma and Immunology, November 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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