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Recent News and Articles on the Keywords: pain + 12,900 + web  Related to the article below (Last Update: 8/5/2008)

NeuroMetrix, Inc. Reports Total Revenues of $8.5 Million for the ...
MarketWatch -
... and that provide regional anesthesia and pain control, announced today its financial results for the three- and six-month periods ended June 30, 2008. ...NURO
Gen. Trask back with 23rd
The Northwest Florida Daily News, FL - Jul 14, 2008
As director, he will oversee 12900 personnel, 133 aircraft and $4 billion in assets. Callan was the first director of the Air, Space and Cyberspace ...
Source: Google News

[BOOK] Achieve Lasting Process Improvement: Reach Six Sigma Goals Without the Pain
BP Lientz, KP Rea - 2002 - books.google.com
... REACH Six SIGMA GOALS ? WITHOUT THE PAIN Bennet P. Lientz Kathryn P. Rea Anderson
Graduate The Consulting Edge, Inc. ... 273 Appendix 4:Web Sites 275 Index 277 ...

Interleukin 18 in acute myocardial infarction -
Y SETA, T KANDA, T TANAKA, M ARAI, K SEKIGUCHI, T … - British Medical Journal, 2000 - heart.bmj.com
... All controls had negative exercise test and none experienced chest pain. ... Leucocytes
4.2 (1.2) 10 (3) 12900 (2000) /mm 3 ... WEB TOP 10 www.heartjnl.com ...

17 Dealing with Death: Euthanasia
J Searle - doi.wiley.com
... to find a way through this complex web of ethics ... there effective ways of controlling
the pain and distress ... deaths in The Netherlands in 1990 12900 Deaths not ...
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17 Dealing with Death: Euthanasia and Related Issues
J Searle - Bioethics for Scientists, 2002 - books.google.com
... to find a way through this complex web ofethics and ... deaths in The Netherlands in
1990 12900 Deaths not ... If the pain and other distressing symptoms of terminal ...
-

Effects of propranolol and nifedipine on exercise-induced attack in patients variant angina: … -
K Kugiyama, H Yasue, Y Horio, Y Morikami, H Fujii, … - Circulation, 1986 - Am Heart Assoc
... http://circ.ahajournals.org located on the World Wide Web at: The online version ...
All patients had attacks of chest pain associated with ST seg- ment elevation ...

[PDF] Conference -
R Annual - Australasian Psychiatry, 1994 - kaisernetwork.org
... Cesar Maurtua, MD, Director of Pain Management, California ... by the US DHHS in response
to the President?s Executive Order 12900, ?Educational Excellence for ...


P Blanck - J. Gender Race & Just., 2004 - HeinOnline
... GOV'T CODE ?? 12900-12996 (1991 & 2003 ... information technology, such as federal web
sites, telecommunications ... The disease causes severe pain when Martin walks ...

[BOOK] Lessons in Law and Aging: A Tool for Educators and Students
MB Kapp - 2001 - Springer Publishing Company

[PDF] An investigation into whether there is ethnic segregation in Bradford
M Goble - dissertations.port.ac.uk
Page 1. Course: BA (Hons) Geography Year: 2006 Author: Maria Goble Tutor: Dominic
Fontana An investigation into whether there is ethnic segregation in Bradford ...

[PDF] NSW Public -
NS Wales - NSW, 2002 - amwac.health.nsw.gov.au
... 25 Page 4. Vol. 14 No. S-3 2 Pain relief 25 Table 14: Confinements by type of
pain relief, NSW 1998?2002 25 Baby Sex 26 Gestational age 26 ...

Source: Google Scholar

How stress alleviates pain

 

One way to alleviate the pain of banging your shin while on a hike is to encounter a grizzly bear—a well-known phenomenon called stress-induced analgesia. Now, researchers have elucidated a key mechanism by which the stress hormone noradrenaline—which floods the bloodstream during grizzly encounters and other stressful events—affects the brain’s pain-processing pathway to produce such analgesia.

Pankaj Sah and colleagues published their findings in the December 6, 2007, issue of the journal Neuron, published by Cell Press.

In an accompanying perspective article on the research, Harvard Medical School researchers Keith Tully, Yan Li, and Vadim Bolshakov wrote that “The impressive new study… provides important mechanistic clues helping to explain this phenomenon.”

In their experiments, Sah and colleagues studied a region of the amygdala, the brain’s emotion-processing region known to mediate the emotional and stress-related aspects of pain. Researchers had long known that these amygdala-based processes were controlled by neurons that originated in the brainstem and that were regulated by noradrenaline.

Sah and colleagues sought in their studies to understand the mechanism by which noradrenaline influences neuronal transmission of pain inputs from the brainstem region known as the pontine parabrachial (PB).

In their experiments with rats, the researchers analyzed the effects of noradrenaline on electrical stimulation of the pathway between the PB and amygdala. They found that noradrenaline acted as a powerful suppressor of that stimulation. The researchers’ studies also revealed that noradrenaline suppression acted on the “transmission” side of the connections between neurons, called synapses. Their analyses revealed how noradrenaline causes such suppression: by activating specific receptors, called adrenocreceptors, on the PB neurons.

The researchers’ studies showed that noradrenaline’s action appears to reduce the number of sites that launch the chemical signals called neurotransmitters by which one neuron triggers a nerve impulse in another, reported the researchers.

They concluded that “Our results show that an important mediator of stress-induced analgesia could be the potent modulation by noradrenaline of [pain] PB inputs in the central amygdala.”

###

The researchers include Andrew J. Delaney, James W. Crane, and Pankaj Sah, of the Queensland Brain Institute, The University of Queensland, Australia.
 
 
 
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