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Recent News and Articles on the Keywords: fungal infections + infections + 0.33  Related to the article below (Last Update: 8/5/2008)

Symptoms of Valley Fever
KPSP, CA -
It's a dust born infection found in dry region, but many of us know very little about it. Valley fever is a fungal infection . Those who live in areas like ...
SGLT2 Inhibitors for the Treatment of Diabetes
Medscape (subscription) -
The possibility of urinary tract infections or genitourinary fungal infections has been raised as a potential concern with this class of drugs; ...
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Edward Owens Buys UnitedHealth Group Inc., Merck & Co. Inc ...
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They have a broad-based focus on developing and marketing drugs to treat patients with infectious diseases including viral infections fungal infections and ...UNH - UNM - MLNM
The importance of feminine hygiene
Malaysia Star, Malaysia - Aug 2, 2008
The most common problem seen is a fungal infection called candidiasis, and thankfully, it is easily treated. Her post childbearing years are when she is ...

Daily Mail
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Prophylactic Use of Specific Antibiotics Reduce the Risk of Some ...
Cancer Consultants, ID - Jul 28, 2008
All patients were treated with coriconazole to prevent fungal infections. Patients were then treated with either no antibiotic prophylaxis, prophylaxis with ...

Best Syndication
Fungal Infection on Your Finger and Toe Nails
Best Syndication, CA - Jul 11, 2008
Nail fungus infection, can damage our finger or toe nails. Most often, these kinds of infections start on the toenails. Why the toenails, you might ask. ...
Key To Virulence Protein Entry Into Host Cells Discovered
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Once inside the plant cell, the proteins suppress the immune system of the plant allowing the infection to progress. The work, which focused on the ...
Source: Google News

Voriconazole Treatment for Less-Common, Emerging, or Refractory Fungal Infections -
JR Perfect, KA Marr, TJ Walsh, RN Greenberg, B … - Clinical Infectious Diseases, 2003 - UChicago Press
... proportion of surviving patients seen here of 0.56 overall (0.33 for disseminated ...
Fungal infections caused by Candida species are major causes of mortality and ...

Significant reduction in the number of fungal infections after lung-, heart-lung, and heart … -
H Reichenspurner, P Gamberg, M Nitschke, H … - Transplantation Proceedings, 1997 - Elsevier
... Patient of all Infections (nl), Fungal Infections (FI), Aspergillus (Asp), and Candida
(Can) Infections After the ... 0.08f o.oo* 0.03 0.33 0.04+ 0.02f ...

Topical treatments for fungal infections of the skin and nails of the foot. -
F Crawford, S Hollis - ncbi.nlm.nih.gov
... using participants who had mycologically diagnosed fungal infections of the ... of treatment
failure for skin infections: allylamines RR 0.33 (95% CI ...

High mortality in systemic fungal infections following renal transplantation in third-world … -
KS Chugh, V Sakhuja, S Jain, P Talwar, M Minz, K … - Nephrology Dialysis Transplantation, 1993 - ERA-EDTA
... The mean number of acute rejection episodes requiring high-dose steroid therapy
prior to detection of fungal infection was 0.88 ?0.33 per patient. ...

… of flowering phenology of Silene alba and S. dioica on susceptibility to fungal infection and seed … -
A Biere, SJ Honders - Oikos, 1996 - JSTOR
... 0.35*** Host size 0.17*** 0.15*** 0.33** 0.17* 0.20 ... the proportion of first-year
infections that became ... Phenology, plant size, and fungal infection The impact ...

Computer analysis of factors influencing frequency of infection in systemic lupus erythematosus -
E Ginzler, H Diamond, D Kaplan, M Weiner, M … - Arthritis Rheum, 1978 - doi.wiley.com
... zoster 2.9 10 6 1.67 0.6 2 6 0.33 ... t Steroid-independent expected number of infections. $
Two patients with coincident bacterial and fungal infection at same ...

Effects of Insect Herbivory and Fungal Endophyte Infection on Competitive Interactions among Grasses -
K Clay, S Marks, GP Cheplick - Ecology, 1993 - JSTOR
... 12 53* 0.40 2.57* E- RF E- PRG 9 65* 0.33 2.87* * denotes ... grasses can be significantly
affected by insect herbivory, fungal en- dophyte infection, and their ...

Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection -
E Dadachova, A Nakouzi, RA Bryan, A Casadevall - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences
... CN is a major fungal pathogenthatcauseslife-threateningmeningoencephalitisin6?8 ... second
model used iv infection of A ... Stomach 2.43 (0.08) 1.04 (0.33) 5.39 (1.32 ...

… with Fluconazole versus Fluconazole Alone for Prophylaxis of Fungal Infections in Adult Patients … -
J Hiemenz, P Cagnoni, D Simpson, S Devine, N Chao, … - Antimicrobial Agents and Chemotherapy, 2005 - pubmedcentral.nih.gov
... of 0.33 to 0.79 liters/kg across the micafungin dose groups. Efficacy. Five out
of 12 (41.7%) patients in the control group had a suspected fungal infection ...

Nosocomial Infections in Combined Medical-Surgical Intensive Care Units in the United States -
MJ Richards, JR Edwards, DH Culver, RP Gaynes - Infection Control and Hospital Epidemiology, 2000 - UChicago Press
... may contribute to the understanding of pathogenic mecha- nisms of the infections
observed. ... Ventilator Major teaching 188,065 0.45 0.28 0.33 0.44 0.53 0.63 ...

Source: Google Scholar

Beating hospital yeast infection

 

Increasing numbers of critically ill patients develop fungal or yeast infections, which are associated with high mortality. Now a review published in the online open access journal, Critical Care, compares treatments involving single-drug antifungal prophylaxis (SAP) or a multi-drug regimen of selective digestive tract decontamination (SDD) and suggests that both methods reduce yeast-related morbidity and mortality, but to different extents.

A team from Academic Medical Center Amsterdam, the Netherlands set out to compare the effectiveness of preventative antifungal therapies by trawling the medical databases. This yielded data from more than 5,500 patients enrolled in over thirty studies. The team compared data on SAP and SDD treatments in critically ill patients, detailing the incidence of yeast colonisation, infection, candidemia, and hospital mortality.

Both SDD and SAP reduced yeast-associated disease among the critically ill. The author’s findings suggest that SDD is more effective than SAP for reducing yeast colonisation and infection, with the exception of candidemia. The latter responded best to SAP. Although both strategies decreased mortality attributable to yeast, SDD led to a significant reduction in all-cause in-hospital mortality.

“Systemic drugs may be advised as prophylaxis in patients with a high risk of developing Candida bloodstream infections, whereas SDD may be given to critically ill patients to prevent Candida colonisation and infection,” the authors suggest.

Effective management of yeast infections is tricky, because diagnostic blood tests are only around 70 percent accurate, and it is hard to differentiate between normal yeast colonies and infection. Previous studies have investigated both SAP and SDD, but to date there has been no direct comparison between the two treatments. In 1995, yeast was reported to be the fourth most common intensive care unit-acquired infection in Europe. It could now be even more common, in lack of more recent data. Candida is also the fourth leading cause of all nosocomial blood stream infections in the USA, accounting for up to 11% of all infections.

###

Notes to Editors:

1) Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review
JW Olivier van Till, Oddeke van Ruler, Bas Lamme, Roy JP Weber, Johannes B Reitsma and Marja A Boermeester
Critical Care (in press)

During embargo, article available at: http://ccforum.com/imedia/2772656961495717_article.pdf?random=289099

After the embargo, article available at journal website: http://ccforum.com/

Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central’s open access policy.

Article citation and URL available on request at press@biomedcentral.com on the day of publication

2) Critical Care is a high quality, peer-reviewed, international clinical medical journal. Critical Care aims to improve the care of critically ill patients by acquiring, discussing, distributing, and promoting evidence-based information relevant to intensivists. The journal is edited by Prof Jean-Louis Vincent (Belgium) and has an Impact Factor of 3.12

3) BioMed Central (www.biomedcentral) is an independent online publishing house committed to providing immediate access without charge to the peer-reviewed biological and medical research it publishes. This commitment is based on the view that open access to research is essential to the rapid and efficient communication of science.

 
 
 
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