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Recent News and Articles on the Keywords: synchrotron + help + save  Related to the article below (Last Update: 8/5/2008)


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TOO HOT TO HANDLE? SYNCHROTRON X-RAY DAMAGE OF LIPID MEMBRANES AND MESOPHASES -
V Cherezov, M Caffrey, O Diat - Biophysical Journal, 2001 - Biophysical Soc
... See Help with Printing for installation instructions. ... rather than opening it "on
the fly." This requires that you configure your browser to "Save" rather than ...

… STRUCTURE INFORMATION CONTENT IN THE VUV REGION OF SYNCHROTRON RADIATION CIRCULAR DICHROISM (SRCD) … -
BA Wallace, RW Janes, A Orry - Biophysical Journal, 2001 - Biophysical Soc
... See Help with Printing for installation instructions. ... rather than opening it "on
the fly." This requires that you configure your browser to "Save" rather than ...

IDENTIFYING HYDROPHOBIC CORE OF PROTEINS BY SYNCHROTRON X-RAY RADIOLYSIS AND MASS SPECTROMETRY
SD Maleknia, W Edstrom, SC Almo, MR Chance - Biophysical Journal, 2001 - Biophysical Soc
... See Help with Printing for installation instructions. ... rather than opening it "on
the fly." This requires that you configure your browser to "Save" rather than ...

SYNCHROTRON RADIATION CIRCULAR DICHROISM (SRCD) AND CD SPECTROSCOPIC STUDIES OF THE VOLTAGE- …
MW Richards, MR Hanlon, NS Berrow, A Butcher, AC … - Biophysical Journal, 2002 - Biophysical Soc
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FOLD RECOGNITION BY SYNCHROTRON RADIATION CIRCULAR DICHROISM (SRCD) SPECTROSCOPY: A NEW TOOL FOR …
BA Wallace, J Lees, RW Janes - Biophysical Journal, 2002 - Biophysical Soc
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Can Synchrotron Light Save the Chip Industry? With US integrated circuit companies reeling under … -
AL ROBINSON - Science, 1986 - sciencemag.org
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SYNCHROTRON X-RAY FOOTPRINTING OF THE TATA BINDING PROTEIN-DNA COMPLEX
H Rashidzadeh, M Brenowitz, MR Chance - Biophysical Journal, 2002 - Biophysical Soc
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SYNCHROTRON X-RAY FOOTPRINTING OF CA2+ ACTIVATED STRUCTURE OF THE HUMAN PLASMA GELSOLIN PROTEIN AS A …
JG Kiselar, SC Almo, MR Chance - Biophysical Journal, 2001 - Biophysical Soc
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… VPU AND ITS FRAGMENTS VPU2-51 AND VPU28-81 IN LANGMUIR MONOLAYERS VIA SYNCHROTRON X-RAY REFLECTIVITY
S Zheng, J Strzalka, C Ma, SJ Opella, BM Oclo, JK … - Biophysical Journal, 2001 - Biophysical Soc
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SYNCHROTRON X-RAY FOOTPRINTING ANALYSIS OF CALCIUM-INDUCED STRUCTURAL CHENGES IN GELSOLIN PROTEIN
JG Kiselar, SC Almo, PA Janmey, W Xian, MR Chance - Biophysical Journal, 2002 - Biophysical Soc
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Source: Google Scholar

Synchrotron could help save the Tassie devil

Dr Church says he will use the synchotron to see if the disease causes any biochemical changes in the devils which could be detected in their hair before the disease becomes apparent.

“If we find a consistent change, it could lead to the development of a test which will allow detection of the cancer before the tumours become evident,” he says. “This would make any quarantine strategy easier to establish, as well as much more efficient.”

The idea is based on Australian research showing disease-related changes in the composition of human hair. The suggestion is that similar changes could occur in Tasmanian devils’ hair when the facial tumour disease is triggered.  “But, the theory needs to be fully tested,” Dr Church says. “It might work or it might not.”

The synchrotron’s infra-red beamline combined with a microscope and spectrometer – which detects how different materials absorb and reflect the radiation – can be used to determine if the composition of hair differs between diseased animals and healthy ones.

“The infra-red spectrum tells us about protein and fat structure and whether it’s changing,” Dr Church says. “But the technology to do such work using a synchrotron is comparatively new, and the Australian facility is one of relatively few around the world where it is available.

“If a diagnostic test for the facial tumour disease using the synchrotron does look possible, only having a machine nearby would make it viable. Having to queue-up for time on a synchrotron at least nine hours flying time from Tasmania – more likely further – would make the whole thing very difficult, particularly in terms of biosecurity concerns because we would need to transport biological samples between different countries.”

Dr Church is one of hundreds of scientists scheduled to use the Australian Synchrotron, which was officially opened in Melbourne yesterday.

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