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Recent News and Articles on the Keywords: gut + 14,400 + 0.23  Related to the article below (Last Update: 8/5/2008)

A cheesehead ponders peaks and witches and dragons
Milwaukee Journal Sentinel, WI - Jul 15, 2008
Hearing their field research eases the anxiety from the levels of say Mt. McKinley (20000 ft) to Mt. Rainier (14400 ft.). Yet, my mind stills swirls with ...
Source: Google News

Alpha-carboxyamidation of antral progastrin. Relation to other post-translational modifications -
L Hilsted, JF Rehfeld - Journal of Biological Chemistry, 1987 - ASBMB
... 5284 (data not shown). All gastrins extended beyond the Gly-93 residue eluted as
a single peak at Kd = 0.23 and were only partly recognized by Ab. 5284. ...

Contaminants and sea ducks in Alaska and the circumpolar region -
CJ Henny, DD Rudis, TJ Roffe, E Robinson-Wilson - Environ. Health Perspect, 1995 - JSTOR
... low- est concentrations were found in the foot, gut/gonad complex ... 3.0+0.5 2.5 (2.9)
13(18) 15(20) 0.23 (0.27) 1100 ... 0.98 Cu 60.8 25-132 Fe 6570 1300-14400 Hg 0.99 ...

Drug glycosides: potential prodrugs for colon-specific drug delivery -
DR Friend, GW Chang - Journal of Medicinal Chemistry, 1985 - pubs.acs.org
... of the gut microflora to hydrolyze glycosides6 (and to re- duce azo bonds), only
recently were drug ... PSI 0.004 11.7 0.23 49.3 0.02 42.5 0.01 12.5 0.11 26.0 ...

Approaches to Assessing Doses to the Embryo and Fetus -
AR Reddy, SC Jain - Radiation Protection Dosimetry, 1998 - NTP
... fetal capil- lary endothelium; G, fetal gut; Li, fetal ... 1360 ? 190 4310 ? 1300 1.02 ?
0.41 0.45 ? 0.23 ... 21.8 ? 34.5 571 ? 291 5850 ? 5360 32900 ? 14400 ...

[PDF] Der SZ-Euroland-Indikator -
M Darstellung, H Bahr - dekabank.de
... Industrieproduktion) hat sich der Wert ? = 14400 und f?r ... beschreibt die konjunkturellen
Schwankun- gen sehr gut, und am ... Mrz 01 -7 51.2 -1.9 0.23 -19.8 -0.11 ...

[PDF] Volkswirtschaft Aktuell -
A vom Trend - dekabank.de
... werden Einzelindikatoren ausgew?hlt, die die Konjunkturschwankungen hinreichend
gut wiedergeben. ... Industrieproduktion) hat sich der Wert ? = 14400 und f?r ...

The role of termites in an equatorial rain forest ecosystem of West Malaysia -
T Matsumoto - Oecologia, 1976 - Springer
... 6. 1.1 14100 640 14740 29900 22.0 0.49 7. 3.3 14200 740 14940 10530 19.2 1.42 8.
2.9 14400 840 15240 23000 17.1 0.66 9. 0.9 10300 600 10900 8300 17.3 1.31 10. ...

Oral Presentations 378?413
CINAP PRESSURE - Intensive Care Medicine, 2001 - Springer
... 384 INTESTINAL PANCREATIC PROTEASE INHIBITION ATTENUATES INTESTINAL ISCHAEMIA-INDUCED
SHOCK BY REDUCING CELL ACTIVATION AND GUT INJURY Fitzal F 1 , Delano FA 2 ...

[PS] Ab-initio-Untersuchungen von UV/VIS-Spektren der Radikal-Kationen von -
P Aromaten, E mit semiempirischen Verfahren - thch.uni-bonn.de
Page 1. Ab-initio-Untersuchungen von UV/VIS-Spektren der Radikal-Kationen
von Polycyclischen Aromaten Berechnung von Eigenschaften der ...

[PDF] Modeling the MHC-I pathway -
DPB Peters - PhD In Thesis (PhD), Berlin, Germany, Humboldt University, 2003 - edoc.hu-berlin.de
... sind die Werte der Paarkoeffizienten klein, was erkl?rt warum Vorhersagen die
Wechselwirkungen komplett vernachl?ssigen trotzdem gut sein k?nnen. ...

Source: Google Scholar

Mucins Provide Protection Against Gut Infections
Mucins are large proteins that are secreted on the surface of the gut, and while long regarded as having a role as a barrier to mucosal infection, data to support this theory have been lacking. In a study appearing online in advance of publication in the August print issue of the Journal of Clinical Investigation, Michael McGuckin and colleagues from the University of Queensland, Australia, show that cell surface mucin 1 (Muc1) plays a critical role in protecting the mucosal lining of the gut from bacterial infection.

These authors orally infected mice with the bacterial pathogen Campylobacter jejuni (a common cause of diarrhea) and found that 1 week after infection this organism could be detected in the organs of the vast majority of mice lacking Muc1, but never in mice with intact Muc1.

Although this organism was able to enter the gastrointestinal epithelial cells lining the gut of both Muc1-deficient and Muc1-intact mice, intestinal damage was more common in Muc1-deficient animals, and the authors determined that the prevention of the spread of infection was exclusively due to Muc1 on the surface of gut epithelial cells. This is believed to be the first study in animals to demonstrate that cell surface mucins are a critical component of mucosal defense, and the role of these proteins in epithelial infections and inflammatory disease should be further examined.

TITLE: MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

AUTHOR CONTACT:
Michael A. McGuckin
University of Queensland, South

Source: Brooke Grindlinger
Journal of Clinical Investigation Brisbane, Queensland, Australia.

 

Possible Link Found Between Memory Storage And Addiction

Our experiences -- the things we see, hear, or do -- can trigger long-term changes in the strength of the connections between nerve cells in our brain, and these persistent changes are how the brain encodes information as memory. As reported in Neuron, Johns Hopkins researchers have discovered a new biochemical mechanism for memory storage, one that may have a connection with addictive behavior.

Previously, the long-term changes in connection were thought to only involve a fast form of electrical signaling in the brain, electrical blips lasting about one-hundredth of a second. Now, neuroscience professor David Linden, Ph.D., and his colleagues have shown another, much slower form of electrical signaling lasting about a second can also be persistently changed by experience.

 

They simulated natural brain activity by applying short electrical jolts to slices of rat brain and measuring the current flowing across the cells. After repeated jolting, the strength of the slow nerve signals had dramatically decreased and remained at a low intensity for 30 minutes after electrical jolts ceased.

These slow signals are produced by a nerve cell receptor called mGluR1, which has been associated with behaviors such as addiction and epilepsy. "Both of these conditions also involve long-term changes in the function of nerve connections," says Linden. "So in addition to furthering our basic understanding of memory storage, our work suggests that drugs designed to alter mGluR1 are promising candidates for the treatment of addiction, epilepsy, and diseases of memory."

The research was funded by the Republic of Korea Ministry of Health and Welfare and the National Institutes of Health

Authors on the paper are Paul Worley and Linden of Johns Hopkins and Sang Jeong Kim, Yunju Jin and Jun Kim of Seoul National University College of Medicine

On the Web:
http://neuroscience.jhu.edu/DavidLinden.php
http://www.neuron.org/

Source: Nick Zagorski
Johns Hopkins Medical Institutions
 
 
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