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Recent News and Articles on the Keywords: parkinsons + early + recognition  Related to the article below (Last Update: 8/5/2008)

The Neglected Side of Parkinson's Disease
RedOrbit, TX - Aug 3, 2008
A weakened sense of smell is not the only possible manifestation of early Parkinson's disease. People with REM behavior disorder frequently have reduced ...
Biotech BOOM
Las Vegas Business Press, NV -
Las Vegas' name recognition may not help either. "The only thing that comes to mind in relation to Las Vegas is entertainment," said Dr. Ivor Royston, ...
Suven Life Sciences Presents Positive Preclinical Data for SUVN ...
PharmaLive.com (press release), PA -
Parkinson's disease and obesity are in addition to developmental candidates in Alzheimer's disease and Schizophrenia. Except for historical information, ...BOM:530239 - NSE:E:SUVEN.EQ
Two compete for vacant St. Charles County Council seat
St. Charles Journal, MO - Jul 30, 2008
By Kalen Ponche After Democrat Tom Fann lost his bid for the 16th District Missouri House seat to Republican Mark Parkinson in February, he was planning a ...
Cambridge Who's Who Supports the Jack Martin Fund
24-7PressRelease.com (press release) - Aug 1, 2008
In addition, the Fund establishes grants to conduct seminal research in heart failure, Parkinson's disease, ileitis and colitis, occupational lung disease ...
Jefferson County Miller deserves recognition
Dreamcricket, NJ - Jul 21, 2008
... became interested in cricket at an early age while attending St. David's Primary School. Later, continuing his studies at Parkinson Secondary School, ...
'Legend' Bob Crampsey dies at 78
The Herald, UK - Jul 27, 2008
Tributes last night poured in for veteran sports broadcaster and writer Bob Crampsey, who has died following a long battle with Parkinson's disease. ...
Hands that shaped Irish history
Irish Times, Ireland - Jul 29, 2008
James Joe Parkinson, biggest racehorse trainer of his time, I knew him because he was in the Curragh. [The Marquess of] Headfort . . . Some characters. ...
After years of waiting, BMX set to go big time
USA Today - Jul 12, 2008
Suffering from early onset Parkinson's disease, he underwent surgery earlier this year to embed a pacemaker-like device in his brain to combat the symptoms ...
Addex Pharmaceuticals Reports First Half 2008 Financial Results ...
Ad-Hoc-News (Pressemitteilung), Germany - Jul 27, 2008
ADX48621, like ADX10059, has potential in multipleindications, but Addex will develop it for levodopa associateddyskinesia in Parkinson's disease patients. ...SWF:ADXN - MRK
Source: Google News

COGNITIVE DEFICITS IN THE EARLY STAGES OF PARKINSON'S DISEASE -
AJ LEES, E SMITH - Brain, 1983 - Oxford Univ Press
... Our study shows that even in the early stages of Parkinson's disease slight ... memory
disturbance could be found on the two-choice recognition memory test. ...

Severe depletion of cocaine recognition sites associated with the dopamine transporter in … -
MJ Kaufman, BK Madras - Synapse, 1991 - doi.wiley.com
... 19901, such probes may detect early stages of ... as deprenyl (Fozard et al., 1985;
Parkinson Study Group ... attenuated in Pd, if cocaine recognition sites associated ...

Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of … -
A Vincent, C Buckley, JM Schott, I Baker, BK Dewar … - Brain, 2004 - pt.wkhealth.com
... Bonnie-Kate 5 ; Detert, Niels 4 ; Clover, Linda 1,2 ; Parkinson, Abigail 1 ... the full
range of clinical presentations and means of early recognition, and optimal ...

Traumatic intracranial aneurysms.
D Parkinson, M West - J Neurosurg, 1980 - ncbi.nlm.nih.gov
... Parkinson D, West M. Eleven cases of traumatic intracranial aneurysms, six saccular ...
Improved mortality depends on early recognition and surgical obliteration. ...

Cognitive impairments associated with early Parkinson's disease -
BE Levin - Neurology, 1989 - AAN Enterprises
... 41 controls to assess the early neuropsychological changes ... Parkinson subjects did
as well as controls on ... on embedded figures, facial recognition, proverbs, and ...

Early cognitive changes and nondementing behavioral abnormalities in Parkinson?s disease -
BE Levin, HL Katzen - Behavioral Neurology of Movement Disorders, 1995 - books.google.com
... these changes are in the early stages of the ... Prism adap -tation, recognition of embedded
facial figures ... 88 PARKINSON'S DISEASE that the earliest visuospatial ...

Pleuropulmonary disease during bromocriptine treatment of Parkinson's disease -
NG McElvaney, PG Wilcox, A Churg, JA Fleetham - Archives of Internal Medicine, 1988 - Am Med Assoc
... disease has been observed in eight patients with Parkinson's disease treated with ...
should be aware of this side effect to ensure early recognition and prompt ...

SSRI-Induced extrapyramidal side-effects and akathisia: implications for treatment -
RM Lane - Journal of Psychopharmacology, 1998 - jop.sagepub.com
... Furthermore, early recognition and appropriate management of EPS and/or ... of EPS in
patients receiving SSRIs does not preclude their use in Parkinson?s ...

Pathologic Gambling in Patients with Parkinson's Disease. -
U Gschwandtner, J Aston, S Renaud, P Fuhr - Clinical Neuropharmacology, 2001 - clinicalneuropharm.com
... theoretic aspect of the dopaminergic reward system, the early recognition of beginning ...
presented at the Sixth International Congress of Parkinson's Disease and ...

Non-motor symptoms of Parkinson's disease: diagnosis and management -
KR Chaudhuri, DG Healy, AHV Schapira - Lancet Neurology, 2006 - Elsevier
... Early recognition of non-motor symptoms is essential for the care of patients with
Parkinson's disease and the importance of a multidisciplinary approach ...

Source: Google Scholar

Early Recognition Of Parkinson's Disease

Specialists of the brain investigation department of the Scientific Research Institute of Neurology, Russian Academy of Medical Sciences, are developing methods for early pre-clinical recognition of Parkinson's disease. The method is based on the fact that even at early stages of the disease, the patients' head, eye and hand movement parameters change.

Parkinson's disease is one of the most widespread neurodegenerative diseases. It develops as a result of injuries of 60 to 80 percent of neurons in a single part of the brain. It is important to find the way to "catch" the disease before neuron degeneration reaches the critical level, and the patient starts suffering from tremor and movement disorders.
To find reliable methods of early diagnostics, the Moscow neurologists examined 12 healthy probationers and 16 patients suffering from the first and the second stages of Parkinson's disease. The participants to the experiment were tested with the help of the hardware and software complex, which analyzes the moving activity. The probationers were (by moving the eyes only) to fix the look on the target, which was shifting across at the angle of 40 degrees. They were suggested to make sliding movements by the head to the left and to the right along the horizontal plane, retaining the look on the target, which moved synchronously with the head movements. And, finally, after several open-eye training sessions, the participants transferred the cursor onto the target by memory, their eyes being curtained off. These three tests allow to check how the patients move separate parts of the body (only eyes, head or hand). In the course of the fourth test, the probationers shifted the cursor from one target to another by moving the eyes, head and hand, i.e. by coordinating their movements.

At the early stage of the disease, individual movements' indices were changed with the patient, but these changes differed slightly from the age standard. However, all parameters of coordinated movement with Parkinson's disease patients reliably differed from those of healthy probationers. Apparently, at the early stage of the disease, the brain is still able to impede the disease development and to compensate for movement disorders. That is why, although each individual movement occurs with a mistake, the mistake is minimal, and it is not always possible to reveal it. However, in case of coordinated movement all these minor delays, inaccuracies in movements and multistage of movements "superimpose" upon each other, and movement disorders become evident.

The researchers assume that it is the coordinated movement disorder that can be considered as one of the markers for early stage of Parkinson's disease. Analysis of such disorders drastically increases the probability of early disease recognition. Nevertheless, the authors of the hypothesis emphasize that this is only a hypothesis so far, and further experiments are need to verify it.

INFORMNAUKA (INFORMSCIENCE) AGENCY
http://www.informnauka.ru/eng

Investigating The Causes Of Parkinson's Disease

A University of Nottingham researcher has been awarded more than £440,000 by the Parkinson's Disease Society (PDS) to investigate the causes of the condition.

Dr Lynn Bedford, of the School of Biomedical Sciences, will lead a five-year study after receiving an award from the PDS under its Career Development Awards Scheme, which aims to support the careers of the UK's most promising individuals working in Parkinson's research.

Dr Bedford will be using a new genetic model of Parkinson's to further understanding of how and why nerve cells die. Her research will also take a closer look at the reasons for the formation of Lewy bodies a build-up of proteins within nerve cells in the brains of people with Parkinson's.

This study is aimed at providing a platform for the development of drugs to stop nerve cell death.

Dr Kieran Breen, Director of Research and Development for the Parkinson's Disease Society, said: "Researchers are the people who make the discoveries and forge the links between different research areas so clearly investing in people is key to furthering our understanding of Parkinson's.

"The Career Development Awards Scheme is aimed at increasing the number of people involved in Parkinson's research and encouraging the UK's top researchers of the future to specialise in Parkinson's."

Parkinson's is a progressive neurological condition caused by the death of nerve cells in the brain that produce the chemical dopamine, which is responsible for movement. The condition affects movements such as walking, talking, and writing. Its three main symptoms are tremor, muscular rigidity, and slowness of movement. Parkinson's is a very individual condition and the rate and nature of progression varies from person to person.

Dr Bedford said: "I have been involved in Parkinson's disease research for the last five years so I am delighted to get this Career Development Award. This novel model of Parkinson's will be crucial in helping to uncover and study why nerve cells die in the region of the brain affected in Parkinson's disease.

"At Nottingham we have an excellent team who are committed to understanding this model. I look forward to driving this interesting new avenue of research and interacting with individuals, both researchers and clinicians, in the field of Parkinson's."

Approximately 120,000 people in the UK have Parkinson's, and 10,000 are diagnosed with the condition every year. Although more common in people aged over 60, about one in 20 of those diagnosed each year are under 40.

Dr Breen added: "The Parkinson's Disease Society is very pleased to be funding Dr Bedford's study. Furthering our understanding of the causes of Parkinson's will hopefully lead to the development of new treatments for the condition, making a difference to the lives of the 120,000 people in the UK with Parkinson's."

The PDS has spent more than £30m on research since 1969, including almost £4m in 2006. Studies funded use basic and applied science as well as health and social care projects to investigate the causes, treatment, prevention and cure for Parkinson's.

The Parkinson's Disease Society (PDS) is the UK's leading authority on all aspects of the condition. The charity campaigns for a better quality of life for people with Parkinson's. The PDS provides field staff and local information and maintains 300 branches.

NOTTINGHAM UNIVERSITY
University Park
Nottingham
NG7 2RD
http://www.nottingham.ac.uk
 
 
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