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Recent News and Articles on the Keywords: bladder + bladders + web  Related to the article below (Last Update: 8/5/2008)

Youth Commission: What to do about bed-wetting
Needham Times,  USA -
This age tends to run in families, and so it is thought that in children who bed-wet after the age of 6, the bladder muscles may not yet be strong enough to ...
Indevus Pharmaceuticals Announces Third Quarter Fiscal 2008 ...
MarketWatch - 19 minutes ago
"We and our partner, Allergan, are very pleased with the launch of SANCTURA XR(TM) in the overactive bladder market. SUPPRELIN(R) LA has continued to exceed ...IDEV
Caples Lake drawdown continues
Amador Ledger-Dispatch, CA -
At this time, the district proposes to mitigate impacts to the fisheries by constructing a temporary "bladder" dam, when the water level is low enough, ...
Patients suffer from painful bladder problem with no cure
Spartanburg Herald Journal (subscription), SC - Jul 22, 2008
By Lindsey Sebastian From bladder pains to frequency and urgency, interstitial cystitis is an inflammation of the bladder due to a defective bladder lining. ...
Antares Pharma to Report 2008 Second Quarter Financial Results on ...
Trading Markets (press release), CA - 11 minutes ago
The Company's lead product candidate, Anturol(TM), an oxybutynin ATD(TM) gel for the treatment of OAB (overactive bladder), is currently under evaluation in ...AIS
Rule out medical problem when housetraining
Pittsburgh Tribune-Review, PA - Jul 26, 2008
If Jonesy is squatting when he urinates, the first thing I recommend that you do is have your veterinarian check his urine for a possible bladder infection. ...
Exceptions expose hypocrisy of rule
The Casper Star Tribune, WY - Aug 1, 2008
Alcoholic will continue to drink even when told their pancreas, liver, kidneys, gall bladder, etc are shot and they will die if they don't quit drinking. ...
UPI NewsTrack Health and Science News
istockAnalyst.com, OR -
4 (UPI) -- US medical scientists say they've determined robotic surgery provides bladder cancer patients with dramatically faster recoveries. ...
Future imperfect
Nashua Telegraph, NH - Aug 3, 2008
... thyroid cancer and lung cancer; those who received radiation in the pelvic area could suffer bladder disease, kidney disease or infertility. ...
Support big ally in fight vs. cancer
Mohave Valley News, NV - Jul 31, 2008
?They diagnosed her with a bladder infection.? The next morning, when the pain was worse, Alyssa returned to the hospital. Alyssa was then given an Magnetic ...
Source: Google News

… S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate … -
LW Harries, MJ Stubbins, D Forman, GC Howard, CR … - Carcinogenesis, 1997 - Oxford Univ Press
... Identification of genetic polymorphisms at the glutathione S- transferase Pi locus
and association with susceptibility to bladder, testicular and prostate ...

Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon … -
S Zhong, AH Wyllie, D Barnes, CR Wolf, NK Spurr - Carcinogenesis, 1993 - Oxford Univ Press
... Press. ARTICLES. Relationship between the GSTM1 genetic polymorphism and
susceptibility to bladder, breast and colon cancer. S Zhong ...

Identifying distinct classes of bladder carcinoma using microarrays -
L Dyrskj?t, T Thykjaer, M Kruh?ffer, JL Jensen, N … - Nature Genetics, 2002 - nature.com
... Figure 3. Molecular classification of bladder tumor stages and identification of
genes ... the right together with the Unigene (Ug) cluster number (see Web Table G ...


WEB Minneapolis - US Patent 3,543,761, 1970 - Google Patents
... BLADDER STIMULATING METHOD 1Claim, 5 Drawing Figs. US CI 128/421, 1 28/4 1 8 Int. ...
3,543,761 12 BLADDER STIMULATING METHOD inside of one of electrodes 18. ...

De novo reconstitution of a functional mammalian urinary bladder by tissue engineering -
F Oberpenning, J Meng, JJ Yoo, A Atala - Nature Biotechnology, 1999 - nature.com
... access provided to: Googlebot Access by: Web Services. ... and seeded onto preformed
bladder-shaped polymers. The native bladders were subsequently excised from ...

Beta-adrenoceptor agonists stimulate endothelial nitric oxide synthase in rat urinary bladder … -
LA Birder, ML Nealen, S Kiss, WC de Groat, MJ … - J Neurosci, 2002 - Soc Neuroscience
... Search for citing articles in: ISI Web of Science (6). ... Adrenoceptor Agonists Stimulate
Endothelial Nitric Oxide Synthase in Rat Urinary Bladder Urothelial Cells. ...

Current Concepts in Biomarker Technology for Bladder Cancers -
M Burchardt, T Burchardt, A Shabsigh, A De La … - Clinical Chemistry, 2000 - Am Assoc Clin Chem
... 2000;46:595-605.) ? 2000 American Association for Clinical Chemistry, Inc. Articles.
Current Concepts in Biomarker Technology for Bladder Cancers. ...

Extracellular Replication of Listeria monocytogenes in the Murine Gall Bladder -
J Hardy, KP Francis, M DeBoer, P Chu, K Gibbs, CH … - Science, 2004 - sciencemag.org
... a browser that does not support current Web standards ... To localize the bacteria in
the gall bladder, we used image-guided histology of infected gall bladders (Fig ...

ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes- … -
DR Ferguson, I Kennedy, TJ Burton - The Journal of Physiology, 1997 - Blackwell Synergy
... the use of isolated urinary bladders mounted in ... The function of suburothelial
myofibroblasts in the bladder. ... (2007) The Uroepithelial-associated sensory web. ...

Cystometric evaluation of bladder dysfunction in elderly diabetic patients -
P Starer, L Libow - Archives of Internal Medicine, 1990 - Am Med Assoc
... because your Web browser does not support basic Web standards. ... presenting with urinary
symptoms have poorly contracting bladders (diabetic bladder). ...

Source: Google Scholar

Scientists move closer to bio-engineered bladders

Researchers at the University of York are using an understanding of the special cells that line the bladder to develop ways of restoring continence to patients with serious bladder conditions, including cancer. The research, highlighted in the quarterly magazine of the Biotechnology and Biological Sciences Research Council (BBSRC) this week, is looking at urothelial cells. These are the specialised lining cells of the bladder that enable it to retain urine. The cells have a very low turnover rate, but scientists have found that if the bladder is damaged, the urothelial cells are able to rapidly re-grow to repair the wound. The researchers hope to harness this property to engineer new bladders.

The York researchers have developed a series of models that mean they can study human urothelial cells in the laboratory. Of these models, the most important is their development of a urothelial cell sheet that functions as it would in the bladder. When the researchers create a wound in this model, the cells regenerate to repair the damage - just as they would in the body.

Pharmaceutical companies should soon be able to use the research models to test therapies for the bladder, but the longer term aim for this research is to help patients who have lost bladder function or have had all or part of their bladder removed because of cancer.

Research leader, Professor Jenny Southgate, explains: "The models we have developed mean that we have been able to examine how urothelial cells in the bladder self-renew to cope with injury.

"With this basic understanding of how the cells work, we are moving towards being able to engineer new bladders. Currently, substitute bladders can be created by using a section of the patient's bowel, but this can lead to complications, as the bowel does not have the same urine-holding properties as urothelial cells. One solution could be to use laboratory-grown urothelial cells to line a section of bowel."

The hope in the long term is that collaborative research to combine Professor Southgate's work with biomaterial studies at the Universities of Durham and Leeds could mean engineered bladder tissue ready for transplantation.

Professor Southgate, who is Director of the Jack Birch Unit for Molecular Carcinogenesis, in the Department of Biology at the University of York said: "Our most exciting work moving forward is to develop natural and synthetic biomaterials that could be combined with regenerating urothelial cells. This has the potential to produce viable bladder tissue for transplant into patients who need replacement bladders."
The York research highlights the importance of basic biology research in underpinning medical advances. Professor Nigel Brown, BBSRC Director of Science and Technology, commented: "Fundamental bioscience research forms the foundation for much of the medical advances we have today and hope for in the future. We need a solid understanding of how our bodies work and maintain themselves before we can understand what goes wrong when they become diseased and how the disease can be treated."
 
 
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