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Recent News and Articles on the Keywords: amnesia + theory + wrong  Related to the article below (Last Update: 8/5/2008)

Dr. W. Gifford-Jones: Should cholesterol drugs be given to 8-year ...
MPNnow.com, NY -
Some critics believe the current theory that cholesterol causes heart disease is dead wrong. Dr. Jim Wright, a British Columbia researcher, says that CLDs ...
Radio review
Stage, UK -
While the lugubrious singer described himself as ?blessed with amnesia,? Marianne recalled every line of every song he dedicated to her with heartbreaking ...
ESCONDIDO: Arizona couple turn to psychics in search for missing son
North County Times, CA - Jul 13, 2008
To Thayla Howard, the amnesia theory makes more sense than other possibilities. She said she is certain her son would not have walked out on his family ...
NY teen overdose spotlights growing heroin problem
Newsday, NY - Jul 19, 2008
Lt. Peter Donohue, a veteran narcotics detective, ascribes to a "generational amnesia" theory. "The kids have been told about the detriment of using cocaine ...
The price of peace
Vanguard, Nigeria - Jul 13, 2008
Apparently the way of peace has a lot to do with developing amnesia of past hurts so we can move on. Forgiveness is a cleansing agent; it opens the door for ...
Health & Fitness : What Causes Short Term Memory And Long Term ...
Prudent Press Agency (press release), Netherlands - Jul 31, 2008
(Prudent Press Agency)---Memory loss or amnesia is an uncommon forgetfulness that can happen due to brain damage. Illness, injury or extreme mental distress ...

The Epoch Times
The Radiant Logic of a Neo-Renaissance Artist
The Epoch Times, NY - Jul 6, 2008
In "My Amnesia," Klein depicts a woman floating peacefully above the skyscrapers of chaotic New York City, separated by a thin film of water that ripples ...
World champs... but not showing it
Independent Online, South Africa - Jul 20, 2008
That may be acceptable for some, but it will be a concern to those who don't suffer from the amnesia which appears to have made so many unaware that the ...
Computer upgrades render information unrecoverable
Vancouver Courier,  Canada - Jul 11, 2008
With her concept of "cultural amnesia," the urban critic predicted we'll eventually reach a peak of technical sophistication, and then negative feedback ...
Democracy: The lessons of history
Boston Globe, United States - Jul 18, 2008
In theory a butcher could serve as head of state, a grocer could vote directly on matters of war and peace. In practice, the system of government by ...
Source: Google News

[BOOK] What's Wrong with Postmodernism: Critical Theory and the Ends of Philosophy
C Norris - 1990 - books.google.com
... What's wrong with postmodernism: critical theory and the ends of philosophy/Christopher
Norris. p. cm-(Parallax) Includes bibliographical references and index. ...

HM, Word Knowledge, and Aging: Support for a New Theory of Long-Term Retrograde Amnesia -
LE James, DG MacKay - Psychological Science, 2001 - Blackwell Synergy
... [meaning] area and time of? (incorrect because lent ... Under an- other theory, progressive
anterograde deficits preceding ... s and Korsakoff?s amnesia cause RA ...

Configural association theory and the hippocampal formation: an appraisal and reconfiguration -
JW Rudy, RJ Sutherland - Hippocampus, 1995 - doi.wiley.com
COMMENTARY Configural Association Theory and the Hippocampal Formation: An Appraisal
and Reconfiguration ... 0 1995 WLEY-USS, ZNC reported that test tlic theory. ...

… Of Emotions: A Contribution From Cognitive Science To The Psychoanalytic Theory Of Therapeutic Acti -
RB Clyman - Journal of the American Psychoanalytic Association, 1991 - PEP Web
... Implications for Psychoanalytic Theory. ... Clinical amnesia, early childhood amnesia,
and repression all preserve ... feels "driven" to reach in the wrong drawer for ...

Transverse Patterning and Human Amnesia -
TC Rickard, M Verfaellie, J Grafman - Journal of Cognitive Neuroscience, 2006 - MIT Press
... which could have an important impact on the cognitive neuroscience of amnesia. ... However,
this interpretation of the configural theory is incorrect, at least ...

… of cognition and memory: A unifying theory of neuromodulator imbalance in psychiatry and amnesia -
C Vakalopoulos - Medical Hypotheses, 2006 - Elsevier
... which abolishes the EEG, induces amnesia for recent ... Evidence from neuromodulator
imbalance: a theory of schizophrenia. ... else, I might carry out the wrong movement ...

[CITATION] Constitutional Amnesia: Judicial Validation of Probable Cause for Arresting the Wrong Person on a …
M Schoenfeld - Wash. ULQ, 2001 - HeinOnline
-

Retrograde Amnesia for Autobiographical Memories and Public Events in Mild and Moderate Alzheimer's … -
M Meeter, EV Eijsackers, JL Mulder - 2006 - ingentaconnect.com
... Critics have often charged that consolidation theory is based on a wrong
view of the data emerging from the study of amnesia. Nadel ...

Talcott Parsons' Marshall Lectures: Contemporay, But Flawed
G Ritzer - Sociological Inquiry, 1991 - Blackwell Synergy
... ?Of Levels and ?Intellectual Amnesia?.? Sociological Theory 7:226-229. ... The
Micro-Macro Problem in Social Theory.? Sociological Theory Wrong, Dennis. ...
-

Response to Alberini: right answer, wrong question -
K Nader, O Hardt, SH Wang - Trends in Neurosciences, 2005 - Elsevier
... Letter. Response to Alberini: right answer, wrong question. ... Such a new theory would
have to encompass: (i) the ... 3 CF Mactutus et al., Retrograde amnesia for old ...

Source: Google Scholar

Forget It: Old Theory On Amnesia May Be Wrong
Forty years of neurobiological research states that short-term memories are formed by modifying proteins, whereas long-term memories are shaped by new proteins. Thus, a class of drugs known to inhibit brain cells from manufacturing proteins are also known to prevent new memory formation, resulting in a form of amnesia.

A new study in Proceedings of the National Academy of Sciences USA could turn this long-held notion on its ear, paving the way to new therapies for Alzheimer's and other diseases that cause dementia and memory loss. While researching the biochemical action triggered by the protein synthesis inhibitor anisomycin in the amygdala (involved in the formation of emotional memories), neuroscientists at the University of Illinois at Urbana-Champaign noted a strange occurrence in the midbrain region.
The levels of three neurotransmitters-norepinephrine, dopamine and serotonin-shot up 1,000 to 17,000 percent higher than their normal levels before abating to well below normal for eight to 48 hours.

"We know that anisomycin causes the large release of neurotransmitters," says senior study author Paul Gold, a professor in the university's Brain and Cognition Division. "Those neurotransmitters themselves regulate memory formation and that's the basis of the particular phenomenon."

Gold and his colleagues began their research on lab rats believing that neurotransmitter fluctuation modulated memory formation. To test their hypothesis, they placed the animals in a cage with one well-lit and one darkened compartment. During the training phase of the experiment, each time a rat ventured into the dark side, they would receive a shock to their feet. Forty-eight hours later, their memory was assessed by their hesitation to enter that compartment.

The team then injected anisomycin and propranolol, a drug that blocks norepinephrine receptors in the brain, into the amygdalae of rats. "We [essentially] blocked the biological consequences of the release of norepinephrine," Gold says, noting that it minimized the rats memory loss evidenced by their reluctance to enter the shock-inducing dark chamber. The amnesia caused by anisomycin was also less pronounced when they injected the rats with clenbuterol, a drug that causes norepinephrine release, when their neurotransmitter levels were low. Finally, when a high dose of norepinephrine was administered in lieu of anisomycin, before training, the excess neurotransmitter levels caused amnesia (just as the protein synthesis inhibitor had).

"Together," the study says, "these findings suggest that intra-amygdala injections of anisomycin interfere with memory formation by inducing extraordinary changes in the release profiles of [norepinephrine, dopamine and serotonin]." Gold adds that follow-up studies will help determine whether all protein synthesis inhibitors have the same effect on neurotransmitters and, also, whether these findings apply to other brain regions.
Yadin Dudai, a neurobiologist at the Weizmann Institute of Science in Rehovot, Israel, notes that protein synthesis has been known to modulate neurotransmitter levels since the 1960s. He adds that the link between novel protein production and memory formation has been observed in several neural circuits in organisms ranging from mollusks to mammals. "I am not confident that the results of this interesting paper indeed demote a dogma," Dudai says. "However, I am supportive of any attempt to reverify the role of macromolecular synthesis observed immediately after the encoding of memory."

According to Gold, if the neurotransmitter fluctuation-based view does demote the dogma, there could be implications for researchers searching for drugs to counteract the effects of dementia that occur in diseases such as Alzheimer's. Researchers will have new targets-neurotransmitters rather than proteins-toward which to tailor their therapies.

By Nikhil Swaminathan

http://sciam.com
 
 
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