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Recent News and Articles on the Keywords: & + news + 2007  Related to the article below (Last Update: 8/5/2008)

District Community Events July 31-Aug. 7, 2008
Washington Post, United States - Jul 31, 2008
FILMS FROM AFGHANISTAN,"Mon Kabul" (2007), a short film about a cabdriver who converses with his male passengers about his beloved city, ...
GIG GUIDE - Show Info
Undertheradar, New Zealand - Aug 2, 2008
Shark in 2007 and stars in C4 TV s new program Jono s New Show that debuted this year. After party to follow at The Pony Club, with a custom ...
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David Erdy did not follow the biggest victory of his budding golf career, the 2007 Evansville Courier & Press Men's City Golf Tournament, with consistent ...
Roundup: $200 Billion Global Data For 2008; $17B EU Content By ...
Washington Post, United States - Jul 23, 2008
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India's Bennett, Coleman Eyeing UK's Trinity Mirror?
Washington Post, United States - Jul 25, 2008
Trinity Mirror has pension liabilities of ?1.53 billion, while it had a ?125 million pension deficit at the end of 2007, which is expected to go up this ...LON:TNI
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Muskegon Chronicle - MLive.com, MI - Jul 25, 2008
Jones gutted and remodeled the former Brunswick Lanes bowling center and opened as the Spotlight in June 2007. Reports of fights, assaults and occasional ...
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Group of veteran Silicon Valley tech and media executives launch ...
24-7PressRelease.com (press release) - Jul 17, 2008
His most recent book, Bill & Dave, was named Best Business Biography of 2007 by 800-ceo-READ. Edgelings.com is a technology news and lifestyle site.
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Source: Google News

The Informational Role of Warranties and Private Disclosure about Product Quality -
SJ Grossman - The Journal of Law and Economics, 1981 - UChicago Press
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Media Discourse and Public Opinion on Nuclear Power: A Constructionist Approach -
WA Gamson, A Modigliani - American Journal of Sociology, 1989 - UChicago Press
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Special Information and Insider Trading -
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R Breton - American Journal of Sociology, 1964 - UChicago Press
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Source: Google Scholar

Inflammatory Joint, Bowel Diseases May Be Linked

Ankylosing spondylitis, inflammatory bowel disorder share common genetics, study suggests

(SOURCE: Arthritis & Rheumatism, news release, July 30, 2007)

MONDAY, July 30 (HealthDay News) -- People whose blood relatives have the joint disease ankylosing spondylitis (AS) are at increased risk not just for AS, but for inflammatory bowel disease (IBD) as well, an Icelandic study shows.

Looking at data from six generations of Icelanders, the researchers discovered a familial link between IBD and AS, an inflammatory disease that primarily affects the spine.

People with AS often suffer from chronic bowel disease and gastrointestinal distress, and both AS and IBD are known to run in families. However, prior to this study, no link had been identified between the two conditions.

According to the researchers, Icelanders provide an ideal study population, because the environmental and lifestyle factors are the same throughout the country. Iceland also maintains an extensive genealogical registry, as well as a half century of records on both AS and IBD sufferers, providing a mine of data for researchers.

Researchers at Landspitali University Hospital, Reykjavik, analyzed the databases for the occurrence of IBD and AS among relatives and the risk of inheriting either and both disorders.

Health information from more than 200 people with AS and more than 1,350 people diagnosed with IBD, as well as genealogic data from more than 790,000 Icelanders, revealed extensive clustering of AS and IBD in families.

First-, second- and third-degree relatives of people with either disorder had increased risks of developing the same disorder, with the risk decreasing as people moved further out on the family tree. First-degree relatives are immediate blood relatives; second-degree relatives are aunts, uncles, nieces, nephews and grandparents; and third-degree relatives are those who share one-eighth of the genetic code, such as first cousins.

The researchers write in the August issue of Arthritis & Rheumatism that the key finding was the increased cross-risk for close relatives of AS and IBD sufferers. In other words, blood relatives of an IBD sufferer also had a greater risk of having AS, and blood relatives of an AS sufferer were at greater risk of IBD. This is the first study to demonstrate a possible hereditary pattern between the two conditions, wrote the researchers, although the specific genetic mechanism has yet to be identified.

"Our results provide strong evidence that a molecular-genetic approach should be utilized in patients with these diseases," the study's lead author, Dr. Bjarni Thjodleifsson, said in a prepared statement. "If this approach proves successful, this will open the possibility of identifying a common early pathophysiologic event in both AS and IBD that may be amenable to new and selective treatments."

The Spondylitis Association of America estimates that there are at least 500,000 people in the United States with AS, although many cases go undiagnosed. Inflammatory bowel disease is thought to affect up to 600,000 people every year.

More information

To learn more about ankylosing spondylitis, visit the Spondylitis Association of America
 
 
 
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