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Recent News and Articles on the Keywords: pain + acetaminophen + eases  Related to the article below (Last Update: 8/5/2008)


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Source: Google News

[PDF] Slow-release morphine eases chronic cough -
AH Morice? - Nursing, 2007 - nursing2007.com
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[CITATION] NEW FOR THE PAIN OF PHARYNGITIS
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[PDF] Musculoskeletal Causes of Low Back Pain in the Elderly -
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[CITATION] Acetaminophen-Codeine Combination Induced Acute Pancreatitis.
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RE: HSMOKING, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS, AND ACETAMINOPHEN IN GASTRIC ULCER? -
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[PDF] Pain -
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Use of NSAIDs, COX-2 Inhibitors, and Acetaminophen and Associated Coprescriptions of … -
E RAHME, MA MARENTETTE, SX KONG, J LELORIER - Arthritis & Rheumatism (Arthritis Care & Research), 2002 - doi.wiley.com
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[PDF] Herpes drug does double duty -
N Nagot? - Nursing, 2007 - nursing2006.com
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Source: Google Scholar

Acetaminophen eases post-wisdom tooth removal pain

Last Updated: 2007-07-30 13:54:14 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Paracetamol (Panadol) , the pain killer known as acetaminophen in the U.S. and sold under the trade names Tylenol in the US and Panadol in the UK, is an effective treatment for the pain following wisdom tooth extraction, according to a review of 21 studies that used the drug to placebo, or an inactive substance.

"It could be considered more readily by dentist and patients both as a first-choice analgesic, or to be taken alternately with doses of other analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs)," Dr. Kiaran Weil of The University of Manchester, UK, and colleagues conclude.

Paracetamol is commonly used to treat pain after wisdom tooth extraction, Weil and his team note. While the drug is frequently classified as an NSAID, they add, its anti-inflammatory effects are "relatively weak" compared to other drugs in the class. However, the drug is effective for pain relief and has few adverse effects.

The researchers conducted a review of the medical literature to gauge the effectiveness of paracetamol compared to placebo for pain relief after removal of the lower wisdom teeth and identify the best dosage and dosing time.

They analyzed 21 trials including 1,968 patients. Four and six hours after taking the drug, the researchers found that patients reported significantly less pain than with placebo. The optimal dosage was 1,000 mg, which the researchers determined could be taken safely every six hours.

Nineteen percent of patients on paracetamol reported adverse events, compared with 16 percent of the placebo group, not a statistically significant difference. The most serious side effect seen with the drug was a severe headache.

The researchers conclude that "Paracetamol is a safe, effective drug for the treatment of postoperative pain following the surgical removal of lower wisdom teeth."

SOURCE: Cochrane Database of Systematic Reviews, 2007, online.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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