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Recent News and Articles on the Keywords: type + 0.30 + web  Related to the article below (Last Update: 8/5/2008)


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Columbia Bancorp Releases Second Quarter Financial Results ...
FOXBusiness - Jul 23, 2008
The webcast can also be heard by going to Columbia Bancorp's Web site, http://www.columbiabancorp.com and selecting Presentations/Webcast under Investor ...
OceanFirst Financial Corp. Announces Another Quarter of Improved ... MarketWatch
First Place Financial Corp. Reports Quarterly Net Income of $2.9 ... Trading Markets (press release)
Synovus Reports Earnings per Share of $0.04 for Second Quarter 2008 MarketWatch
Trading Markets (press release)
all 1,034 news articles »  OTC:CMTX - CBBO - FPFC
High Fiber in Pregnancy Cuts Risk of Preeclampsia
Medscape (subscription) - Jul 21, 2008
Associations of similar magnitude were seen when they looked at highest vs lowest quartiles of water-soluble fiber (relative risk [RR] 0.30) and insoluble ...
CenturyTel Reports Second Quarter 2008 Earnings
MSN Money - Jul 31, 2008
"We continue to evaluate deployment and technology alternatives for our 700 MHz spectrum and are currently leaning toward the same type of LTE-based ...CTL - WAR:CFL
Wintrust Financial Corporation Reports Second Quarter 2008 Earnings
PR Newswire (press release), NY - Jul 23, 2008
On a ratio basis, annualized net charge-offs as a percentage of average loans were 0.36% in the second quarter of 2008, 0.30% in the first quarter of 2008 ...WTFC - MSM:FINC

In order to show you the most relevant results, we have omitted some entries very similar to the 4 already displayed.
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Source: Google News

Creating Adaptive Web Sites Through Usage-Based Clustering of URLs -
B Mobasher, R Cooley, J Srivastava - Proceedings of the 1999 Workshop on Knowledge and Data …, 1999 - doi.ieeecs.org
... an architecture for automatic Web personalization based on Web usage data ... user sessions,
for example, to isolate specific types of "content ... 0.32 /grad-info 0.30 ...

Silk from a sow's ear: extracting usable structures from the Web -
P Pirolli, J Pitkow, R Rao - Proceedings of the SIGCHI conference on Human factors in …, 1996 - portal.acm.org
... Node Type Size Number Number Depth Similari Freq ... Home Page + + + + 0.30 Personal
Home > 1 k & < 3 ... to extract characteristics directly from the Web server's file ...

Rate of change and other metrics: a live study of the world wide web -
F Douglis, A Feldmann, B Krishnamurthy, J Mogul - Proceedings of the USENIX Symposium on Internet Technologies …, 1997 - portal.acm.org
... How much duplication is there in the Web? ... (b) Grouped by content type. time (in sec.)
between access and last modified ... 0.25 0.30 1sec 1min 1hour 1day 1mo 1year ...

Curriculum Sequencing in a Web-Based Tutor -
MK Stern, BP Woolf - Intelligence Tutoring System (Proc. 4th Int'l Conf. ITS'98) - Springer
... Page 6. Curriculum Sequencing in a Web-Based Tutor 579 ... Node Link Type Threshold Needed
Student 1 Student 2 Student 3 A Prerequisite 0.8 0.75 0.81 0.30 ...

… Alternative to Ultracentrifugal and Electrophoretic Methods in the Diagnosis of Familial Type III … -
T Wang, K Nakajima, ET Leary, GR Warnick, JS Cohn, … - Clinical Chemistry, 1999 - Am Assoc Clin Chem
... 0.69 ( 0.30 when using mg/dL) correctly classified 94% and 90% of the subjects,
respectively. The utility of the RLP-C-to-total TG ratio in diagnosing type III ...

… gels for ANG II type-1 receptor A1166C polymorphism Article published online before print. See web … -
CCJ HUNT, JE BURLEY, CML CHAPMAN, JP BEILBY - Physiological Genomics, 1999 - Am Physiological Soc
... 1. ANG II type-1 receptor (AT 1 ) A1166C ... 9% CC; the allele frequencies were 0.70
A and 0.30 C and ... See web site for date of publication (http://physiolgenomics ...

Measuring the Independence of Central Banks and Its Effect on Policy Outcomes -
A Cukierman, SB Web, B Neyapti - The World Bank Economic Review, 1992 - World Bank
... These considerations were embodied in a "type-of- limit" variable and also ... Legal
central bank in- depen- dence" (index) 0.33 0.33 0.31 0.30 0.30 0.30 0.29 0.29 ...

Characterising and profiling health Web user and site types: going beyond ??hits?? -
P Huntington, D Nicholas, P Williams - Aslib Proceedings, 2003 - ingentaconnect.com
... 30-44,000 119 1.76t* 0.30 85 1.08 0.36 ... ``Staying fit and healthy?? type user 0.72 ...
Characterising and profiling health Web user and site types Paul Huntington ...

Web information seeking by pages: An observational study of moving and stopping
J Kari - Information Research, 2004 - informationr.net
... between the subject and language of Web pages, whereas ... Variable Y, Subject, Language,
Content type, Tactic, Strategy, ... Subject, 0.53**, 0.30**, ?, 0.32**, 0.25**, ...

Using clustering techniques to detect usage patterns in a Web-based information system -
HM Chen, MD Cooper - Journal of the American Society for Information Science and …, 2001 - doi.wiley.com
... Error variables TE The number of different types of errors made during a session
NE The number of Web pages containing text about errors that the system ...

Source: Google Scholar

Genetics Discovery Should Improve Treatments And Preventive Measures For Type 1 Diabetes In Children
Pediatrics researchers at The Children's Hospital of Philadelphia and McGill University in Montreal have identified a gene variant that raises a child's risk for type 1 diabetes, formerly called juvenile diabetes. As investigators continue to pinpoint genes contributing to diabetes, they have their eyes on providing a scientific basis for designing better treatments and preventive measures for the disease.

The research adds a new gene and new knowledge to the four genes previously discovered for type 1 diabetes, in which the immune system destroys insulin-producing beta cells in the pancreas and makes patients dependent on frequent insulin injections to keep the body's blood sugar under control. As the project continues, the study team expects to identify additional genes (perhaps as many as 15 or 20) thought to interact with each other in the disease.
The study appeared in an advance online letter in the journal Nature.

"The genotyping technology we now have available has revolutionized the way we can ask and answer research questions," said the study's lead author, Hakon Hakonarson, M.D., Ph.D., the director of the Center for Applied Genomics at The Children's Hospital of Philadelphia. "Unlike the previous technology, which was quite limited and dealt largely with relatively rare gene variants, we can now detect common genetic variants that are important in large numbers of individuals, and begin to understand how multiple genes interact in complex diseases such as diabetes."

In the discovery phase of the study, the investigators examined the genomes of 1,046 children with type 1 diabetes. These DNA samples came from patients and families followed in pediatric diabetes clinics in Philadelphia and four Canadian cities. Specifically, the researchers compared the genomes of 563 patients with type 1 diabetes with those of 1,146 matched control subjects. Those results were combined with those obtained from an independent analysis of 483 family trios, in which the genomes of a child with the disease and both parents were examined.

The researchers confirmed the four previously identified locations for genes contributing to type 1 diabetes, but also uncovered a new type 1 diabetes locus on chromosome 16, occupied by a gene called KIAA0350. The team then replicated this discovery in yet another independent cohort of 1,333 children with the disease from the Type 1 Diabetes Genetics Consortium, which includes children of European descent in Europe, North America and Australia, as well as in 390 additional type 1 diabetes family trios from Canada.

Constantin Polychronakos, M.D., director of Pediatric Endocrinology at McGill University and senior author of the study, said that better knowledge of genes that predispose to type 1 diabetes may later enable physicians to screen newborns to predict those at high risk for the disease.

The gene implicated in the current research, KIAA0350, is known to be active almost exclusively in immune cells. Although scientists do not currently know the exact function of the protein the gene encodes, other research has predicted that it produces a protein called C-type lectin that is located on the surface of immune cells and binds to groups of sugars in the body.

"The role of KIAA0350 needs to be investigated," said Hakonarson. "However, a special cell type called a natural killer (NK) cell expresses this gene abundantly, although at different levels based on these gene variants. Our hypothesis is that a special mutation in KIAA0350 may influence the sugar binding of the protein, and trigger an autoimmune response that activates these NK cells in such a way that they attack and destroy the islet cells in the pancreas, resulting in type 1 diabetes. A particular version of the gene protects against this inappropriate autoimmune response, while a different version of the gene makes it more likely to happen. "
Although much research remains to be done, better understanding of the disease process may guide doctors to new and improved therapies. "If we know the gene pathways that give rise to type 1 diabetes, we hope to intervene early in life with targeted drugs or cell therapies to prevent the disease from developing," said Polychronakos.

The current research used a technique called genome-wide association, in which highly automated analytic equipment rapidly scans each patient's DNA for more than half a million genetic markers. It was performed at the Center for Applied Genomics at Children's Hospital. The Center's tools spell out a patient's genotype -- the specific pattern of variations among an individual's 30,000 genes. Established in the summer of 2006, the center is taking on one of the largest genotyping projects in the world, and is the largest one dedicated to genetic analysis of childhood diseases.

"This study is the first one that our center has published on a gene associated with a complex childhood disease, but we have many projects under way and several other papers in press," said Hakonarson. "Our goal at the Center is to discover the major disease-causing variants and genes that influence complex pediatric diseases, thus providing a scientific foundation that is based in biology for translating those discoveries into successful treatments."

Among its current projects, the Center's investigators are focused on identifying genes involved in pediatric asthma, allergy, obesity, attention-deficit hyperactivity disorder, autism, inflammatory bowel disease, hypertension, juvenile rheumatoid arthritis and the pediatric cancer neuroblastoma. The Center recently contributed 4,000 DNA samples to an industry-hosted database that serves as a free repository of control samples for researchers seeking gene variations in diseases.

Financial support for the study came from Genome Canada through the Ontario Genomics Institute, the Juvenile Diabetes Research Foundation and The Children's Hospital of Philadelphia. Hakonarson's and Polychronakos' co-authors were affiliated with the University of Pennsylvania School of Medicine, the University of Manitoba, the Children's Hospital of Eastern Ontario, the University of Ottawa, and Markham-Stoufville Hospital of Markham, Ontario.

About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 430-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu/.

Source: John Ascenzi
Children's Hospital of Philadelphia
 
 
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