Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California



 

Recent News and Articles on the Keywords: new + faseb + web  Related to the article below (Last Update: 8/5/2008)

Wiley-Blackwell: Wiley-Blackwell Announces New Publishing ...
Trading Markets (press release), CA - Jul 17, 2008
Wiley's global headquarters are located in Hoboken, New Jersey, with operations in the US, Europe, Asia, Canada, and Australia. The Company's Web site can ...JW.A - OTC:CMTX
Richard Marchase of UAB to lead top bioscience federation
The Birmingham News - al.com, AL - Jul 21, 2008
Richard Marchase, a top UAB scientist and administrator, has been named president of the Federation of American Society for Experimental Biology, or FASEB, ...
Ask Dr. Weil: No link between MSG and health ills
Arizona Daily Star, AZ - Jul 15, 2008
A comprehensive review of the scientific data conducted from 1992 to 1995 by the Federation of American Societies for Experimental Biology (FASEB), ...
Source: Google News

… induced by viral vector-mediated overexpression of human alpha-synuclein: A new primate model of … -
D Kirik, LE Annett, C Burger, N Muzyczka, RJ … - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences
... opportunities for the study of pathogenetic mechanisms and exploration of new
therapeutic targets ... Home page, FASEB J. Home page J. Klucken, TF Outeiro, P. Nguyen ...

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell … -
G Nocentini, L Giunchi, S Ronchetti, LT Krausz, A … - Proceedings of the National Academy of Sciences, 1997 - National Acad Sciences
... Thus, GITR is a new member of tumor necrosis factor/nerve growth factor receptor ...
Home page, FASEB J. Home page KM Baltz, M. Krusch, A. Bringmann, P. Brossart, F ...

A new approach for the electrophoretic detection of apoptosis -
BA Eldadah, AG Yakovlev, AI Faden - Nucleic Acids Research - Oxford Univ Press
... incubation for 5 min at room temperature and centrifugation over a new microfuge
tube ... Home page, FASEB J. Home page JW ALLEN, SM KNOBLACH, and AI FADEN Combined ...

[CITATION] Web term papers and Chime: A new way of presenting of structural information
SC Hartsel - Faseb Journal, 1997

Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene -
YX Pan, J Xu, L Mahurter, E Bolan, M Xu, GW … - Proceedings of the National Academy of Sciences, 2001 - National Acad Sciences
... should be addressed at: Memorial Sloan-Kettering Cancer Center, 1275 York Avenue,
New York, NY ... Home page, FASEB J. Home page HS Choi, CS Kim, CK Hwang, KY Song ...

A new class of genome rare cutters -
AG Veselkov, VV Demidov, PE Nielson, MD Frank- … - Nucleic Acids Research - Oxford Univ Press
... VCH, New York, NY, pp. ... Home page, FASEB J. Home page A. RAY and B. NORD?N Peptide
nucleic acid (PNA): its medical and biotechnical applications and promise for ...

Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes … -
C Gustafsson, R Reid, PJ Greene, DV Santi - Nucleic Acids Research - Oxford Univ Press
... suggests new family members and reveals highly conserved motifs and a domain structure
similar to other nucleic acid amino-methyltransferases FASEB J, November ...

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the … -
CW So, C Caldas, MM Liu, SJ Chen, QH Huang, LJ Gu, … - Proceedings of the National Academy of Sciences, 1997 - National Acad Sciences
... We have identified a new partner gene, EEN, fused to MLL in a ... Home page, FASEB J.
Home page A. Shilatifard Factors regulating the transcriptional elongation ...

A new class of obesity genes encodes leukocyte adhesion receptors -
ZM Dong, JC Gutierrez-Ramos, A Coxon, TN Mayadas, … - Proceedings of the National Academy of Sciences, 1997 - National Acad Sciences
A new class of obesity genes encodes leukocyte adhesion receptors. ... Home page, FASEB
J. Home page A. INUI Transgenic study of energy homeostasis equation ...

Protein folding Web alert -
P Wittung-Stafshede - Chemistry & Biology, 2000 - Elsevier
... genome projects are identifying thousands of new protein sequences ... second ? the focus
of this Web alert ? is ... The FASEB Society has a valuable essay (aimed ...

Source: Google Scholar

New target for HIV/AIDS drugs and vaccines discovered
Article in The FASEB Journal shows how HIV delivers a one-two punch to cells of the innate immune system

Bethesda, MD--Researchers from Rome, Italy, describe a finding in the August 2007 print issue of The FASEB Journal that could lead to new drugs to fight the HIV/AIDS virus, as well as new vaccines to prevent infection. It has been known that HIV proteins disable the antibody-forming part of the immune system (the “homeland defense” or acquired immune system). In this report, researchers demonstrate for the first time how the HIV-1 Nef viral protein delivers a one-two punch to the body’s  innate immune system (our “early warning system” composed of dendritic and natural killer cells). First, Nef hijacks dendritic cells (DCs) to upset the function of natural killer (NK) cells. Second, after blocking this first line of defense against the immune system, Nef uses DCs and NK cells to create a microenvironment that actually makes it easier for HIV/AIDS to replicate.
According to Maria Giovanna Quaranta of Instituto Superiore de Sanità and first author of the article, “The findings described in this work may have several implications for AIDS treatment: the understanding of Nef function, mechanism of action, and cellular partners might aid the discovery of suitable drugs able to block the activity of this smart protein.” Quaranta added, “An exciting possibility is the design of a vaccine including a mutated Nef protein unable to assist the virus in the control of its host.”

The research findings also raise another intriguing possibility: Nef proteins may be able to boost or suppress DC and NK cell activity. If so, it may prove to be a valuable new therapeutic approach for people with diseases and disorders that involve overactive or underactive immune responses. DCs and NK cells play critical roles in the body’s initial defense against infection. DCs are instrumental in identifying foreign invaders to the body and then orchestrating an immune response that ultimately removes them. NK cells are among the first cells summoned by DCs to help isolate and contain the infection until more potent reinforcements can be manufactured to eradicate the virus or bacteria. When DC cells can no longer adequately “manage” the immune response and when NK cells can no longer contain infections, the likelihood of survival without medical intervention is relatively low.

“HIV’s relatively rapid evolution has given it an ability to handle all our bodies can throw at it and more,” said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal. “Now that we know how the viral protein disables the innate as well as the acquired arm of our immune system, we can begin to design decoy proteins or to devise new vaccines. Millions of lives depend on our finding a way to restore both aspects of our immune defense against HIV/AIDS—this study should go a long way toward that goal.”

The FASEB Journal is published by the Federation of American Societies for Experimental Biology (FASEB) and is consistently ranked among the top three biology journals worldwide by the Institute for Scientific Information. FASEB comprises 21 nonprofit societies with more than 80,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB advances biological science through collaborative advocacy for research policies that promote scientific progress and education and lead to improvements in human health.

###
FOR IMMEDIATE RELEASE

CONTACT:
Cody Mooneyhan
Managing Editor
Tel: 1-301-634-7104
E-mail: cmooneyhan@faseb.org
 
 
Google
Web www.iconocast.com

Search inside Iconocast for the keyword you have in mind.

Iconocast has collected more than 50,000 articles and press releases on health and science.

These are current and most up to date press releases on the subject you are searching.

We collect current health and science press releases daily from more than 5000 research and health institutes. Here is an example : The elderberry way to perfect skin

We believe if you do search inside Iconocast, you will get better results than searching the web alone.

 
 
Continue News With: News4 ; News5 ; News6 ; News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services.

 

Iconocast Home Page

Contact Iconocast

© 2003-07. ICONOCAST is a trademark of iconocast.com.