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Recent News and Articles on the Keywords: news + cancer + anderson  Related to the article below (Last Update: 8/5/2008)

Early screening is crucial to improving recovery rates for breast ...
Orlando Sentinel, FL -
"As you age, your risk of developing breast cancer increases," says Dr. Nikita Shah, director of the breast-cancer unit at MD Anderson Cancer Center Orlando ...
12000 new cancer cases in Cameroon annually
MyNews.in, India -
The shocking revelation was made recently by the executive secretary of Cameroon National Cancer Control Programme, Anderson Sama Doh. ...
Golf tournament to benefit cancer patients
Laconia Citizen, NH - Aug 4, 2008
... Lynn and Jerry Anderson established the Anderson Pharmacy Fund for oncology patients at LRGHealthcare to help pay the medication costs for cancer ...
Cancer Doctor Takes a Stand on Cell Phone Use: Advises Precautions
Ergoweb, UT -
By Jennifer Anderson The head of a prominent cancer research institute isn?t waiting for a conclusive link to be made between cancer and cell phone use. ...
Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer
Washington Post, United States - Aug 1, 2008
... author Dr. Raymond Dubois, provost and executive vice president of the University of Texas MD Anderson Cancer Center, said in a university news release. ...
Breast CT Scans Could Be Comfortable Alternative to Mammograms Washington Post
all 31 news articles »
NASCAR AT RIVERHEAD: Anderson's big day ends a little too soon
Newsday, NY - Aug 3, 2008
That was the year his father, also a racecar driver, was stricken with cancer. Anderson spent all his time that summer shuttling between the hospital and ...

Country Hound
New Keith Anderson Release Reflects Sorrow
Country Hound, TN -
As Keith Anderson was finishing up his sophomore effort?hoping to follow the success of Three Chord Country and American Rock & Roll?his mother was ...
On a 'Re-Mission' to save lives of kids with cancer
USA Today - Aug 3, 2008
... young adults have lagged behind those of other age groups, says Anna Franklin of the Children's Cancer Center at Houston's MD Anderson Cancer Center. ...
Jerry Kill staying course at Northern Illinois
Chicago Tribune, United States - Aug 3, 2008
By John Mullin | Chicago Tribune reporter Justin Anderson just shakes his head at the memory of one Jerry Kill moment in particular. ...

Enews 2.0
Many Sunscreens Fail To Offer Protection Against Sun?s Rays
Enews 2.0, UK -
By Diane Anderson A market research company called Mintel carried out a study on over 750 sunscreens, and discovered that most of the products fail to ...
Source: Google News

Linkage of early-onset familial breast cancer to chromosome 17q21 -
… Lee, B Newman, JE Morrow, LA Anderson, B Huey, MC … - Science, 1990 - sciencemag.org
... 60: 2411-2418 | Abstract ? | Full Text ? Familial Breast and Ovarian Cancer: A Swedish
Population-based Register Study. H. Anderson, A. Bladstrom, H. Olsson ...

Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health … -
GL Anderson, M Limacher, AR Assaf, T Bassford, SA … - JAMA, 2004 - Mass Med Soc
... Our physician-editors offer you clinical perspectives on key research and news. ... plus
progestin) has no significant impact on breast cancer risk ... Anderson GL et al ...

The concordance between the clinical trials assay (CTA) and fluorescence in situ hybridization (FISH … -
… , K Charlene, L Johnson, T Everett, S Anderson - Proc Am Soc Clin Oncol, 2000 - asco.org
... Mass, Corsee Sanders, Kasian Charlene, Lori Johnson, Tajuana Everett, Steve Anderson. ...
for enrollment in the pivotal Herceptin metastatic breast cancer trials. ...

[PDF] Gene therapy scores against cancer -
WF Anderson - Nat Med, 2000 - cmbi.bjmu.edu.cn
... NEWS & VIEWS ... Alternative cancer therapy approaches have been based on oncolytic viruses,
which selec- tively attack tumor, but not normal, cells. ...
-

Breaking Bad News About Cancer: Patients' Preferences for Communication -
PA Parker, WF Baile, C de Moor, R Lenzi, AP … - Journal of Clinical Oncology, 2001 - jco.ascopubs.org
... believed that the context of how the news was told ... by stage of disease or whether
the cancer had recurred. ... fact that patients who come to MD Anderson or other ...

SPIKES--A Six-Step Protocol for Delivering Bad News: Application to the Patient with Cancer -
WF Baile, R Buckman, R Lenzi, G Glober, EA Beale, … - The Oncologist, 2000 - theoncologist.org
... learn to break bad news by observing more experienced colleagues in clinical situations
[39]. At the University of Texas MD Anderson Cancer Center we used the ...

Low-Fat Dietary Pattern and Risk of Colorectal Cancer: The Women's Health Initiative Randomized … -
… LG Snetsclaar, HR Black, GL Anderson, ALR Assaf, T … - Obstetrical & Gynecological Survey, 2006 - obgynsurvey.com
... Mara Z. Vitolins, Garnet L. Anderson, Annlouise R ... density and fractures, and breast
and colorectal cancer. Almost every newspaper and news magazine journalist ...

Deep venous thrombosis and occult malignancy: an epidemiological study -
… Nordstrom, B Lindblad, H Anderson, D Bergqvist, T … - BMJ, 1994 - Mass Med Soc
... offer you clinical perspectives on key research and news. ... Home>; Primary Care>; General
Medicine>; Summary and Comment. DOES VENOUS THROMBOSIS MEAN OCCULT CANCER ...

Phorbol esters increase the amount of Ca 2, phospholipid-dependent protein kinase associated with … -
AS Kraft, WB Anderson - Nature, 1983 - nature.com
... | PubMed | ISI | ChemPort |. 5. Wertz, PW & Mueller, GL Cancer Res. 38, 2900-2904
(1978). ... 11. Kraft, AS, Anderson, WB, Cooper, HL & Sando, JJ J. biol. Chem. ...

Preventing medication errors in cancer chemotherapy. -
MR Cohen, RW Anderson, RM Attilio, L Green, RJ … - American Journal of Health-System Pharmacy, 1996 - pt.wkhealth.com
... Division of Pharmacy, University of Texas MD Anderson Cancer Center, Houston. ... for
the administration and use of cancer chemotherapeutic agents ... Pharm Pract News. ...

Source: Google Scholar

Natural Protein Protects Against Cancer

Harnessing IKKa could fight skin tumors, other malignancies, scientists say

(SOURCE: University of Texas M.D. Anderson Cancer Center, news release, July 19, 2007)

TUESDAY, July 24 (HealthDay News) -- Researchers have identified a protein that plays a key role in preventing skin cancer cells from dividing and multiplying.

Writing in the July 20 issue of Molecular Cell, a team at the University of Texas M.D. Anderson Cancer Center, reported that the protein IKKa prevented a vital "checkpoint" gene from shutting down and allowing cancer cells to spread.

The protein often is absent or only found at lower levels in a type of skin cancer cell.

IKKa is found at lower than normal levels in aggressive squamous cell carcinomas in both mice and humans. When operating normally, it allows the checkpoint gene 14-3-3o to respond to DNA damage in the cell. The gene usually creates a protein that blocks defective cells from dividing, allowing genetic errors to be repaired rather than copied.

Without IKKa proteins, the gene does not function optimally, and cells that multiply with damaged or abnormal genes are the root of cancer.

The interaction is part of the process of DNA methylation -- a process by which the work of a gene is chemically altered, but the gene itself is not damaged. Researchers look for ways to chemically turn the gene back on and restore its function.

The team inserted IKKa into deficient cells, which allowed the checkpoint gene to work again.

"What we've identified is a mechanism that promotes genetic instability in keratinocytes, a critical type of skin cell that makes up 90 percent of epidermal cells, during the development of human skin cancers," Yinling Hu, senior author of the paper and assistant professor in M.D. Anderson's department of carcinogenesis at the Science Park-Research Division in Smithville, Texas, said in a prepared statement. "Our finding opens a new avenue for identifying new therapeutic targets for battling cancer," Hu said.

The findings may have implications for a broad array of cancers, as the researchers noted that the checkpoint gene 14-3-3o is also shut down in cancerous epithelial cells. Epithelial cells are found in the outer layer of skin and in the linings of other body organs such as lungs, and the gastrointestinal, reproductive and urinary tracts.

More information

To learn about DNA methylation, visit the Epigenetics Society

 
 
 
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