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Recent News and Articles on the Keywords: healthday + 21,400 + web  Related to the article below (Last Update: 8/5/2008)

Immunotherapy Boosts Treatment of Kids' High-Risk Sarcomas
Washington Post, United States -
4 (HealthDay News) -- Immunotherapy shows promise in treating children with high-risk sarcomas, according to a US National Institute of Health pilot study. ...
Blood-Thinner Plavix Works Harder in Smokers
U.S. News & World Report, DC -
4 (HealthDay News) -- The widely used anti-clotting drug Plavix appears to have a stronger effect in people who smoke, a study indicates. ...
Researchers Push Aggressive Cholesterol Control in Kids
Washington Post, United States -
4 (HealthDay News) -- Programs to lower cholesterol from childhood on could lower rates of coronary artery disease and save lives, according to a review ...
Immigrant Children Less Likely to Exercise
U.S. News & World Report, DC -
4 (HealthDay News) -- Immigrant children in the United States are less active and less likely to participate in sports than US-born children, says a federal ...
Injected Drug Approved for High Blood Pressure
Forbes, NY -
4 (HealthDay News) -- The US Food and Drug Administration has approved Cleviprex (clevidipine butyrate), an injected drug to treat high blood pressure. ...
Health Tip: Good Health for Men
U.S. News & World Report, DC -
(HealthDay News) -- While risk factors, age and family history play a role in a man's health, your daily habits and health regimen also have a major impact ...
Children in Blended Families Still Close to Biological Mothers
Washington Post, United States -
4 (HealthDay News) -- With few exceptions, stepchildren and those in other non-traditional families featuring the kids' biological mother spend as much time ...
Many Cancer Patients Turn to Complementary Medicine
U.S. News & World Report, DC -
4 (HealthDay News) -- As many as 61 percent of cancer patients use complementary therapies such as prayer, relaxation, meditation and massage, ...
Excessive Drinking Boosts Risk for Metabolic Syndrome
U.S. News & World Report, DC -
4 (HealthDay News) -- People who drink too much have increased odds of developing metabolic syndrome, a series of risk factors and conditions that are ...
Many Kids Under 15 Watch Violent Movies
Washington Post, United States -
4 (HealthDay News) -- A large proportion of American adolescents are getting early and regular exposure to violent movies, a new survey reveals. ...
Source: Google News

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[CITATION] Lowering co-pays on some drugs help fight chronic diseases
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[CITATION] Unused prescription drugs don? e to go to waste. HealthDay. 2004; Apr 10
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[CITATION] Hospital injuries kill 32,000 in US each year. HealthDay News
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[CITATION] HealthDay News, 29 August 2005
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[PDF] Stem-Cell Therapy Restores Movement in Paralyzed Mice -
EJ Mundell, HD Reporter - alsbc.ca
... Stem-Cell Therapy Restores Movement in Paralyzed Mice By EJ Mundell HealthDay
Reporter Jun 21, 2006 ... By EJ Mundell HealthDay Reporter ...

World health day
IJ Pediat - Indian Journal of Pediatrics, 1967 - Springer
... NOTES World Health Day ... of technicians of a great many different disciplines: It is
to these "partners in health" that WHO dedicates World HealthDay in 1967. ...

[CITATION] Higher Taxes Help Smokers Kick The Habit
R Dotinga - HealthDay Reporter, 2005

[CITATION] You?ve (Still) Got Male: Boys with Genital Defects, Raised as Girls, Revert Back to Original Gender
R Dotinga - HealthDay News, 2004

Source: Google Scholar

Newer Breast Cancer Drugs Appear to Boost Life Spans

Aromotase inhibitors and other chemo drugs add months to lives, Canadian study reports.

By Randy Dotinga
HealthDay Reporter

 

(SOURCES: Stephen Chia, M.D., medical oncologist, British Columbia Cancer Agency, Vancouver, Canada; Eric Winer, M.D., director, Breast Oncology Center, Dana-Farber Cancer Institute, Boston; Sept. 1, 2007, Cancer)

MONDAY, July 23 (HealthDay News) -- A newer generation of breast cancer medications added months to the lives of patients with the most advanced form of the disease, according to the first study of its kind.

Still, the prognosis for the patients remains grim, with the exception of those who have a particular type of cancer that responds well to a new drug. And, one expert noted, the study did not include the newer cancer drug Herceptin, which has proven to prolong women's lives.

Even so, "this provides encouragement to patients with metastatic breast cancer" who were the focus of the study, said lead author Dr. Stephen Chia, a medical oncologist at the British Columbia Cancer Agency. "We can tell them that we have more drugs available, and it appears they do allow them to live longer."

Breast cancer is the most commonly diagnosed type of cancer, and only lung cancer kills more women.

Researchers have had a difficult time figuring out whether newer drugs, including the class called aromatase inhibitors, are effective for the most serious forms of breast cancer. It's considered unethical to assign one group of terminal cancer patients to a drug and give others a placebo or simply keep them comfortable.

"We're making a leap of faith as to what we're doing, how we're spending our resources, that we're actually allowing them to live longer," Chia said.

The new study looked at patients in the Canadian province of British Columbia between 1991 and 2001. All the 2,150 women had metastatic breast cancer, meaning tumors had spread beyond the breast.

The researchers found that the average survival time in the 1991-1992 and 1994-1995 periods was fairly stable, at 438 and 450 days, respectively. But when new drugs became available in the middle of the decade, survival grew to 564 days (1997-1998) and 667 days (1999-2001).

The newer medications included chemotherapy drugs and drugs known as aromatase inhibitors that tinker with estrogen levels. The study doesn't prove conclusively that the drugs lead to higher life spans, but the authors wrote that it seems likely.

An increase in life span of about eight months may not seem like much. But Chia pointed out that it's an average, and some women live longer.

In addition, he said, the newer drugs appear to be easier on patients, so they have better quality of life during their final days.

The results are in the Sept. 1 issue of the journal Cancer.

Dr. Eric Winer, director of the Breast Oncology Center at the Dana-Farber Cancer Institute in Boston, said the newer drugs are, indeed, easier for patients to tolerate.

"They're not only more effective, but they're kinder and gentler than they used to be. On a daily basis, our waiting room is filled with women, many of whom have advanced breast cancer but don't look different from those with early stages of breast cancer," he said.

But Winer noted that the study, which was first reported four years ago, is a bit outdated, because it was done before Herceptin (trastuzumab) was approved in 1998.

Herceptin allows about a quarter of women with breast cancer to survive for years, he said. The drug works best in those with HER2-positive cancer.

But, he added, "There are many women who are only living a year or two or three with this illness. We want it to be much better than that."

Meanwhile, another study published in the journal followed up on a previous study assessing the value of group therapy in breast cancer patients.

The case-control trial found that patients in weekly group therapy had only similar survival rates to those given literature-based patient education.

But the study also found that group therapy improved the quality of life for women with estrogen-receptor-negative tumors.

More information

Learn more about breast cancer from the National Cancer Institute.

 
 
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