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Recent News and Articles on the Keywords: prostate + improved + pathology  Related to the article below (Last Update: 8/5/2008)

/REPEAT -- Diagnocure announces the formation of a new Strategic ...
Canada NewsWire (press release), Canada -
Current standard of care requires that pathologists examine microscopically a thin slice of tissue from the lymph nodes harvested during the patient's ...TSE:CUR - GPRO
HealthTronics Acquires UroPath, LLC
MarketWatch - Jul 21, 2008
Founded in 2003, UroPath is a leading provider of anatomical pathology laboratory services in the US In 2007, labs managed by UroPath processed over 400000 ...HTRN
Lawsuit to be filed against hospital authority
The Northern Light, Canada - Jul 22, 2008
MONCTON - Patients who feel that they have been harmed by misdiagnosis, error and a lack of quality control at a Miramichi hospital pathology lab are taking ...
Fourth International Consultation On Incontinence (ICI) - Surgery ...
Medical News Today (press release), UK - Jul 26, 2008
Cystoscopy may be useful to rule out urethral stricture and bladder pathology. While urodynamics (UDS) with or without fluoroscopy is commonly performed for ...
Laboratory Corp. of America Holdings Q2 2008 Earnings Call Transcript
Seeking Alpha, NY - Jul 24, 2008
Study report that vitamin D deficiencies increase risk of prostate, colon, and breast cancer as well as osteoporosis. Here again the laboratory industry ...LH
Miramichi health authority names Menon's successor
Times and Transcript, Canada - Jul 17, 2008
Butany was in Ottawa on Wednesday to release new guidelines to improve pathology services across Canada. The recommendations include hiring 500 pathologists ...
Amgen, Inc. Q2 2008 Earnings Call Transcript
Seeking Alpha, NY - Jul 28, 2008
Same for the enrollment of the study designed to explore the effect of denosumab on skeletal pathology in patients with prostate cancer that has metastasis ...AMGN
PCa Immunotherapy Combo Promising
Renal and Urology News, NY - Jul 22, 2008
The researchers believe that the combination of these two immunotherapies increases one's immunity to prostate cancer. It is thought the two drugs together ...
Defining The Urologic Chronic Pelvic Pain Syndromes: A New ...
Medical News Today (press release), UK - Jul 18, 2008
Subsets of patients may be described in the future, perhaps with the aid of the MAPP program, by disease specific terms as pathology and phenotype become ...
SEHA implements new electronic medical records system
ArabianBusiness.com (press release), United Arab Emirates - Jul 20, 2008
The Cerner Millennium solutions implemented at Tawam Hospital automate processes in the radiology, pathology, pharmacy, surgery, emergency, and scheduling ...
Source: Google News

Pathology residents' use of a Web-based tutorial to improve Gleason grading of prostate carcinoma on … -
JD Kronz, MA Silberman, WC Allsbrook, SI Bastacky, … - Human Pathology, 2000 - Elsevier
... The aim of this study was to develop a free, widely available, Web-based program
to improve pathology residents? ability to Gleason grade prostate cancer on ...

Postoperative Radiotherapy for Stage pT3 Carcinoma of the Prostate: Improved Local Control. -
I Syndikus, T Pickles, E Kostashuk, LD Sullivan - The Journal of Urology, 1996 - jurology.com
... Pathology TOP. ... It remains to be seen whether early hormonal therapy [14] or
postoperative radiotherapy to the prostate can improve the outcome. ...

Tissue Microarrays: What Will They Bring to Molecular and Anatomic Pathology? -
H Moch, J Kononen, OP Kallioniemi, G Sauter - Advances in Anatomic Pathology, 2001 - anatomicpathology.com
... coworkers contained samples from normal prostate or benign ... optimization of probes
and antibodies, improved utilization of pathology archives and ...

Prostate cancer: effect of postbiopsy hemorrhage on interpretation of MR images. -
S White, H Hricak, R Forstner, J Kurhanewicz, DB … - Radiology, 1995 - ncbi.nlm.nih.gov
... AND METHODS: Seventy-three patients with biopsy-proved prostate cancer were divided ...
but the positive predictive value for extracapsular extension was improved. ...

… of poorly differentiated and non-organ-confined prostate cancer compared with prostate-specific … -
F Recker, MK Kwiatkowski, T Piironen, K Pettersson … - Urology, 2000 - ncbi.nlm.nih.gov
Click here to read Human glandular kallikrein as a tool to improve discrimination
of poorly differentiated and non-organ-confined prostate cancer compared with ...

Reproducibility of Gleason grading of prostate cancer can be improved by the use of reference images … -
L Egevad - Urology, 2001 - ncbi.nlm.nih.gov
... to read Reproducibility of Gleason grading of prostate cancer can be improved by
the use of reference images. Egevad L. Department of Pathology and Cytology ...

… technique dose escalation for prostate cancer: biochemical evidence of improved cancer control with … -
GE Hanks, WR Lee, AL Hanlon, M Hunt, E Kaplan, BE … - Int J Radiat Oncol Biol Phys, 1996 - ncbi.nlm.nih.gov
... Conformal technique dose escalation for prostate cancer: biochemical evidence of
improved cancer control with higher doses in patients with pretreatment ...

… FAILURE OR ADVERSE PATHOLOGY AFTER RADICAL PROSTATECTOMY THAN PROSTATE SPECIFIC ANTIGEN OR GLEASON … -
SJ FREEDLAND, GS CSATHY, F DOREY, WJ ARONSON - The Journal of Urology, 2002 - Elsevier
... A computerized pathology diagnosis coding system instituted ... grades, which may have
improved predictive accuracy ... indicated that percent of prostate biopsy tissue ...

… and seminal vesicle involvement based on clinical and biopsy findings in prostate cancer in Japanese … -
S Egawa, K Suyama, K Matsumoto, T Satoh, T Uchida, … - Urology, 1998 - ncbi.nlm.nih.gov
... Improved predictability of extracapsular extension and seminal vesicle involvement
based on clinical and biopsy findings in prostate cancer in Japanese men. ...

… of a 21-sample needle biopsy procedure designed to improve the prostate cancer detection rate. -
A de la Taille, P Antiphon, L Salomon, M Cherfan, … - Urology, 2003 - ncbi.nlm.nih.gov
2003 Jun;61(6):1181-6. Click here to read Prospective evaluation of a 21-sample
needle biopsy procedure designed to improve the prostate cancer detection rate. ...

Source: Google Scholar

Improved Prediction Of Prostate Cancer Recurrence Through Systems Pathology

UroToday.com- Dr. Cordon-Cardo and collaborators report development of systems pathology that incorporates clinical and pathologic variables to predict prostate cancer (CaP) recurrence. Their work appears in the online version of the Journal of Clinical Investigation.

Systems pathology is a methodology that uses object-oriented image analysis, pattern recognition, and quantitative biomarker multiplexing that are analyzed by supervised machine learning algorithms. An initial study based upon 323 patients identified that high levels of androgen receptor as identified by immunohistochemical staining were correlated with a reduced time to PSA recurrence.
This was then combined with the pathologic variables of biopsy Gleason score, seminal vesicle invasion, extracapsular extension, primary radical prostatectomy Gleason score, and preoperative PSA in addition to the texture of epithelial nuclei and cytoplasm in tumor areas for the systems pathology platform.

A validation study was performed in 366 patients but only 61 of these had adequate tissue in the microarrays to be included. PSA recurrence was found in 26 of the 61 men (43%). The model applied to these 61 patients demonstrated a sensitivity of 96% and a specificity of 72% for the detection of PSA recurrence by 5 years post surgery.

The authors comment that this approach provides an aspect of personalized medicine to help decision-making.

Cordon-Cardo C, Kotsianti A, Verbel DA, Teverovskiy M, Capodieci P, Hamann S, Jeffers Y, Clayton M, Elkhettabi F, Khan FM, Sapir M, Bayer-Zubek V, Vengrenyuk Y, Fogarsi S, Saidi O, Reuter VE, Scher HI, Kattan MW, jr. Bianco FJ, Wheeler TM, Ayala GE, Scardino PT, Donovan MJ

J Clin Invest. ePub, June 7, 2007
Doi: 10.1172/JCI31399

Reported by UroToday.com Contributing Editor Christopher P. Evans, M.D

UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice.
 
 
 
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