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Recent News and Articles on the Keywords: stem + cells + embryonic  Related to the article below (Last Update: 8/5/2008)


ABC News
Defying Western Science, Chinese Biotech Pursues Untested Stem ...
InformationWeek, NY -
The company, Beike Biotechnology, uses non-embryonic stem cells to treat a variety of ailments including heart disease and neurological disorders such as ...
Pro-Life Bioethicst Applauds Recent Advance Using iPS Cells to ... LifeNews.com
Scientists create first personalized stem cells in ALS patients Los Angeles Times
Stem-cell advance reported Seattle Times
Boston Globe - Medical News Today (press release)
all 129 news articles »  OTC:SCII
UGA stem cell researchers awarded $9.2M grant
Bizjournals.com, NC -
NIGMS launched its efforts to explore human embryonic stem cells in 2003. The agency awarded a total of $27 million this year for research at UGA, ...
University of Wisconsin researchers get grant to study stem cells
Milwaukee Journal Sentinel, WI -
The reprogrammed cells, derived without the destruction of human embryos, share essential characteristics of embryonic stem cells: immortality and ...
UW-Madison granted nearly $9 million for stem cell research The Capital Times
NEW $8.9 MILLION PROJECT AIMS TO UNLOCK STEM CELL SECRETS Wisbusiness.com
UW-Madison receives $8.9 million stem-cell grant WTN News
all 5 news articles »
South Korea Prohibits Hwang Woo-Suk From Embryonic Stem Cell Research
LifeNews.com, MT -
In December, that company asked for permission from the country's government to proceed with an new embryonic stem cell research project that uses "aborted ...

ABC News
Agreement on big issues
Washington Times, DC -
John McCain are prepared to overturn President Bush's policy and expand federal funding for embryonic stem cell research, one of a series of contentious ...
AssociatedPress
Dobson, Mohler concerned about Obama Southern Baptist Theological Seminary Towers Online
all 757 news articles »

LifeNews.com
Mich. Board Sets Hearing To Decide If Measure Loosening Stem Cell ...
Medical News Today (press release), UK -
21 meeting to review signatures submitted for state ballot initiatives, including a proposal to loosen state restrictions on human embryonic stem cell ...
Michigan Panel to Decide This Month on Human Embryo Research Proposal LifeNews.com
all 2 news articles »
Brighter Smiles: Can teeth save lives?
Amesbury News, MA -
Where are stem cells? There are embryonic, umbilical, bone marrow, and dental pulp stem cells. Embryonic stem cells are the most controversial. ...
Two Stanford Faculty Will Benefit from Keck Awards
MarketWatch -
The Keck award will allow her to study how members of a pivotal group of enzymes turn genes on during the transition from embryonic stem cells to mature ...
Bono Mack lauds new research on stem cells from fat
The Desert Sun, CA -
"It?s removing the political controversy," Bono Mack said, referring to some lawmakers' opposition to embryonic stem cell research. ...

News24.com
South Korea Rejects Request to Resume Stem Cell Study (Update1)
Bloomberg - Jul 31, 2008
... rejected a request by a company headed by Hwang Woo Suk, the scientist who faked studies on human embryonic stem cells, to resume research in the field. ...
Korea: Seoul Rejects Hwang's Project On Stem Cells Sin Chew Jit Poh
South Korea rejects disgraced clone scientist's license Reuters
Disgraced SKorean scientist won't resume cell work The Associated Press
KBS - TopNews
all 81 news articles »
Source: Google News

Embryonic Stem Cell Lines Derived from Human Blastocysts -
JA Thomson, J Itskovitz-Eldor, SS Shapiro, MA … - Science, 1998 - sciencemag.org
... that have normal karyotypes, express high levels of telomerase activity, and express
cell surface markers that characterize primate embryonic stem cells but do ...

Derivation of Completely Cell Culture-Derived Mice from Early-Passage Embryonic Stem Cells -
A Nagy, J Rossant, R Nagy, W Abramow-Newerly, JC … - Proceedings of the National Academy of Sciences of the …, 1993 - JSTOR
Derivation of Completely Cell Culture-Derived Mice from Early-Passage Embryonic
Stem Cells. Andras Nagy. Janet Rossant. Reka Nagy. Wanda Abramow-Newerly. ...

… cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells -
GR Martin - Proceedings of the National Academy of Sciences of the …, 1981 - JSTOR
... 7638, December 1981 Developmental Biology Isolation of a pluripotent cell line f
cultured in medium conditioned by stem cells (embryonic stem cells/inner cell ...

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor … -
J Nichols, B Zevnik, K Anastassiadis, H Niwa, D … - Developmental Cell, 2004 - cell.com
... Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic
Stem Cells Ian Chambers, Douglas Colby, Morag Robertson, Jennifer Nichols ...
-

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk … -
TC Doetschman, H Eistetter, M Katz, W Schmidt, R … - J Embryol Exp Morphol, 1985 - ncbi.nlm.nih.gov
... The in vitro developmental potential of embryonic stem cell lines and the consistency
with which the cells express this potential are presented as aspects ...

Derivation of Pluripotent Stem Cells From Cultured Human Primordial Germ Cells. -
MJ Shamblott, J Axelman, S Wang, EM Bugg, JW … - Obstetrical & Gynecological Survey, 1999 - obgynsurvey.com
... So far, embryonic sources have yielded two types of pluripotent stem cells: embryonic
stem (ES) cells derived from the inner cell mass of preimplantation ...

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro -
BE Reubinoff, MF Pera, CY Fong, A Trounson, A … - Nature Biotechnology, 2000 - nature.com
... Embryonic stem cells provide a model to study early human embryology, an
investigational tool for discovery of novel growth factors and medicines, and a ...

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides -
AG Smith, JK Heath, DD Donaldson, GG Wong, J … - Nature, 1988 - nature.com
... Murine embryonic stem (ES) cells are pluripotent cell lines established directly
from the early embryo 1,2 which can contribute differentiated progeny to all ...

Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. -
J Yamashita, H Itoh, M Hirashima, M Ogawa, S … - Nature, 2000 - ncbi.nlm.nih.gov
Click here to read Comment in: Nature. 2000 Nov 2;408(6808):43, 45. Flk1-positive
cells derived from embryonic stem cells serve as vascular progenitors. ...

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells -
RL Williams, DJ Hilton, S Pease, TA Willson, CL … - Nature, 1988 - palgrave-journals.com
... 10.1038/336684a0. Myeloid leukaemia inhibitory factor maintains the developmental
potential of embryonic stem cells. R. Lindsay Williams ...

Source: Google Scholar

Discovery May Change The Future Of Human Embryonic Stem Cells Research

A startling discovery on the development of human embryonic stem cells by scientists at McMaster University will change how future research in the area is done.

An article published in the prestigious scientific journal Nature this week reports on a new understanding of the growth of human stem cells. It had been thought previously that stem cells are directly influenced by cells in the local environment or 'niche', but the situation may be more complex. Human embryonic stem cells are perpetual machines that generate fuel for life.
In this week's Nature, researchers of the McMaster Cancer and Stem Cell Research Institute show that human embryonic stem (ES) cells can actually produce distinctive niche cells, which then release stem-cell nourishing proteins to help keep their 'parents' ticking over.

Scientific Director Mick Bhatia and colleagues provide the first evidence that human ES cells have the unique ability to generate human-ES-cell-derived fibroblast-like niche cells (hdFs) in vitro despite removal from their in vivo microenvironment. These hdFs then provide a continuous source of supportive proteins, including insulin-like growth factor 2 (IGF-II), which they now show could be 'the' protein to sustain hESCs..

Researchers are interested in the relationship between stem cells and their niche, because the niche represents a route for modifying stem cell behaviour -- if human ES cells can be reliably guided down a particular pathway, then they can be more readily used for future clinical therapy to regenerate damaged tissue such as neurons for Parkinson's disease, or insulin producing cells for diabetes .

The research has been funded by the Canadian Institutes for Health Research and the National Cancer Institute of Canada.

The Nature article is the latest in a series of important papers published by scientists at the 18-month-old institute, which was established with funding by philanthropist Michael G. DeGroote. The institute has a research focus on the molecular determinants of cancer and tissue repair and is building scientific momentum.
"This discovery of a new fundamental understanding about how human stem cells develop is the kind of scientific work which has already put this Institute on the map as the leader in this field," said John Kelton, dean and vice-president of McMaster's Faculty of Health Sciences.

Mick Bhatia said that he and his scientific team have been working for the past year to prove themselves wrong, but as every test confirmed their discovery, it was time to submit the work for international peer review from other experts.

"This will be critical for future developments involving drug and gene screening of human ES cells, that will be required before clinical use of human stem cells of this kind," he said.

The paper was published electronically on Nature's website and will be published in print later this month.

McMaster University, a world-renowned, research-intensive university, fosters a culture of innovation, and a commitment to discovery and learning in teaching, research and scholarship. Based in Hamilton, the University, one of only four Canadian universities to be listed on the Top 100 universities in the world, has a student population of more than 23,000, and an alumni population of more than 125,000 in 125 countries.

Note: available for downloading at http://www.fhs.mcmaster.ca/media.htm

* Colour pictures of human stem cells

* Short video of human stem cell development

* Graphic of how human stem cell develops niche cells which provide nourishment to stem cell

* Pictures of scientists of McMaster Stem Cell and Cancer Research Institute

Source: Veronica McGuire
McMaster University
 
 
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