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Recent News and Articles on the Keywords: 1,350,000 + 0.31 + web  Related to the article below (Last Update: 8/5/2008)

Jacques Kerrest Joins ActivIdentity as Chief Financial Officer and ...
CNNMoney.com -
The options entitle Mr. Kerrest to purchase, outside of the Company's stockholder-approved equity incentive plans, an aggregate of up to 1350000 shares of ...ACTI
HCP Announces Second Quarter 2008 Results
WELT ONLINE, Germany -
... net 504126 516133 Total assets $ 12223730 $ 12521772 Liabilities and Stockholders? Equity Bank line of credit $ ? $ 951700 Bridge loan 1150000 1350000 ...HCP - THC
Quarterly Activities Report
Sydney Morning Herald, Australia - Jul 29, 2008
... 21200000 1.8 380000 Dredge Inferred Resources - 1% HM Cut off Bidaminna 44600000 3.0 1350000 Titan 115400000 1.9 2210000 Calypso 51500000 1.7 850000 Sub ...ASX:IMA
Superior Uniform Group Reports Continued Improvement in Operating ...
MarketWatch - Jul 24, 2008
... 1638883 Taxes on income 1350000 590000 ------------ ------------ Earnings from continuing operations 2125612 1048883 Loss from discontinued operations, ...SGC
American Tower Corporation Reports Second Quarter 2008 Financial ...
WELT ONLINE, Germany - Jul 30, 2008
... from issuance of Certificates in securitization transaction - 1750000 Borrowings under credit facilities 475000 1350000 Repayments of notes payable, ...AMT - WAR:CFL

Easier (press release)
Vision becomes reality at Woodham Park
Easier (press release), UK - Jul 28, 2008
One of the properties, Millmead House, backs onto the canal and enjoys its own mooring, and is on the market for ?1350000 while Hatherton House is available ...
Shuffle Master Inc (SHFL) holdings reduced by Strs Ohio
Mffais.com, CA - Jul 25, 2008
LONG BEACH (Mffais.com) - Strs Ohio sold -1350000 (-100.00 %) of their shares in Shuffle Master Inc (SHFL), bringing their current holdings to 0 shares as ...SHFL
302nd AEG conducts its 21st day of California wild fire support
Air Force Link, DC - Jul 17, 2008
The 302nd AEG aerial assets have conducted 985 drops in the current fire fighting operations, dispensing more than 1350000 gallons of fire retardant and ...
Jeremy Joseph defends Chip Lead ? Felix catches up ? Gus bluffs ...
PokerStrategy.com, UK - Jul 12, 2008
Immediately behind him are Gus Hansen (1360000) and Victor Ramdin (1350000) on ranks 20 and 21. Allen Cunningham gathered 1270000 chips and lies on rank 25. ...
Incyte Announces Proposed Public Offering of 9000000 Shares of ...
Centre Daily Times, PA - Jul 29, 2008
In connection with the offering, the Company expects to grant the underwriters a 30-day option to purchase an additional 1350000 shares of common stock from ...INCY
Source: Google News

LATCH HUB ASSEMBLY -
AC BONORA - EP Patent 1,350,000, 2003 - freepatentsonline.com
Patent Number: Advanced Search. Site Contents. Search Patents Use our search engine
to find what you need. Data and Analytical Services Complete custom solutions ...
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US Patent 1,350,000, 1920 - Google Patents
Page 1. 1,350,000. H, BATES, 'TYPEWRITING MACHINE. APPLICATION FILED MAR. 15; 1919, ...
Page 4. 1,350,000 ? of the line (illustrated as letter-space 40 in ...

Carbonate turbidites deposited on the floor of the Palau Trench
S YAMAMOTO, H TOKUYAMA, K FUJIOKA, A TAKEUCHI, H … - Marine geology, 1988 - cat.inist.fr
... chimique; Chemical composition; An?lisis qu?mico; Dissolution; Solution; Disoluci?n;
Fosse Palau; Carotte KH 86-1 P-2; N 074500 N 074500 E 1350000 E 1350000 ...

Value of the alert and action lines on the partogram. -
B Dujardin, I De Schampheleire, H Sene, F Ndiaye - Lancet, 1992 - ncbi.nlm.nih.gov
... PMID: 1350000 [PubMed - indexed for MEDLINE]

Surface acoustic waves as a technique for in-line detection of processing damage to low-k … -
F Iacopi, SH Brongersma, A Mazurenko, H Struyf, G … - ieeexplore.ieee.org
... SiOC:H -B blanket ^Stiffening effect -5"N2M2 - 5" 02/CF4 - pristine 950000 1150000
1350000 1550000 1750000 Wavevectorfm"1) Fig.3 SAWs dispersion on blanket SiOC ...

[CITATION] Australian Tuna Fleet in the Western Pacific: Implications for Industry and Fisheries Management
A Mcllgorm - Economics of Fishery Management in the Pacific Islands …, 1989 - Hyperion Books

Morphology and intersections of crazes in polystyrene films -
CC Chau, LC Rubens, EB Bradford - Journal of Materials Science, 1985 - Springer
... Six different poly- styrenes with the weight average molecular weight ranging from
46900 to 1350000 were used as listed in Table I. A spherical stretcher was ...
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?? ? ? ?? ? ? ?? ?? ? DPSO ? ?? ? ?? ?? ? ??? RC ? ? ?? ??
????, ???? ?, ????, ??? ? - ?? ?? ?? ? F, 2006 - J-STAGE
Page 1. DPSO RC 1 2 3 4 1 755-8611 2-16-1 E-mail: hisao@mituwa.net 2
239-8686 1-10-20 3 755-8611 2-16-1 4 755-8611 2-16-1 GAs(Genetic ...
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How the rheological properties of solutions of graft copolymers depend on the length and number of …
NN Druzhinina, MP Pen'kova, RM Livshits, ZA … - Fibre Chemistry, 1971 - Springer
... 00 13,7 86,3 19,6 80,4 76,5 74,8 62 63 53 7 ,1 78,3 81,2 71,9 M of ak chain 1350000
770000 500000 168000 2O0OO0 ... 10 0 11 1350000 12 770000 13 500000 14 45O00 ...
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Source: Google Scholar

Inhibition Of A Chemical In The Brain Could Result In A Novel Therapeutic Strategy For Obesity
A fat-derived protein known for its effects on the liver and skeletal muscle might also serve as an energy-conserving signal to the brain during periods of starvation, suggests a new study in the July issue of Cell Metabolism, a publication of Cell Press. The substance, known as adiponectin, acts on the brain to boost appetite and slow energy expenditure in an effort to maintain adequate fat stores during lean times, the researchers report.

"Energy homeostasis may be mediated by both short-term regulators, such as gut hormones, and long-term regulators," said Takashi Kadowaki of the University of Tokyo. "In this study, we identified, for the first time, a potential long-term regulator that allows energy to be stored efficiently, namely, adiponectin." The findings offer critical insight into adiponectin's influence over the central nervous system and suggest that selective inhibition of the chemical in the brain may represent a novel therapeutic strategy for obesity and obesity-linked diseases, he added.
White adipose tissue (WAT) is a major site of energy storage and plays an important role in energy balance, the researchers said. It is also recognized as an important endocrine organ that secretes a number of biologically active signaling proteins, called adipokines. Adiponectin, an adipokine secreted exclusively by WAT, is present at relatively high concentrations in the circulation and has been shown to increase the body's response to insulin. Studies have also suggested that decreased circulating levels of adiponectin in obesity and type 2 diabetes may contribute to the insulin resistance that characterizes both conditions.

In addition to its peripheral actions on the liver and skeletal muscle, adiponectin has also been reported to have central actions, Kadowaki said. Recently, however, it was reported that adiponectin is undetectable in human cerebrospinal fluid and does not cross the blood-brain barrier, leaving some doubt about its physiological role in the central nervous system, he added.

The researchers now report evidence in mice that adiponectin receptors are present in the hypothalamic region of the brain and that some forms of the chemical enter the cerebrospinal fluid from the blood. Once in the brain, adiponectin enhances the activity of a metabolic enzyme called AMP-activated protein kinase (AMPK) to stimulate greater food consumption. Moreover, the researchers found that adiponectin decreased energy expenditure. They also showed that blood and spinal fluid adiponectin levels in the brain normally increase during fasting and decrease after refeeding, suggesting that adiponectin acts mainly during food shortages.

In adiponectin-deficient mice, AMPK activity in the brain slowed, causing the animals to eat less and expend more energy. That action, in turn, made the animals resistant to becoming obese even on a high-fat diet. Moreover, animals lacking adiponectin lost more fat after 12 hours of fasting than normal mice did.

Blood levels of another fat hormone, leptin, are regulated inversely in relation to serum adiponectin levels, the researchers noted.

"Thus, central adiponectin/leptin signals may represent the physiological pathway by which hypothalamic AMPK activity and food intake are stimulated during fasting and suppressed after refeeding," they said. "In addition to this short-term regulation of food intake and energy expenditure by adiponectin and leptin, these two adipokines may also participate in the long-term regulation of energy homeostasis. The fundamental roles of leptin and adiponectin seem to be to preserve an adequate fat reserve: leptin acts as a satiety signal, and adiponectin acts as a starvation signal."
The researchers include Naoto Kubota, Iseki Takamoto, and Takashi Kadowaki of the University of Tokyo, CREST, Japan Science and Technology Corporation, and the National Institute of Health and Nutrition in Tokyo, Japan; Wataru Yano, Shinsuke Itoh, Hiroki Kumagai, Hideki Kozono, Hidemi Satoh, Atsushi Tsuchida, Ryozo Nagai, and Kohjiro Ueki of the University of Tokyo in Tokyo, Japan; Tetsuya Kubota of the University of Tokyo, National Institute of Health and Nutrition, and Toho University, Ohashi Hospital in Tokyo, Japan; Toshimasa Yamauchi, Ryo Suzuki, Kazuyuki Tobe of the University of Tokyo, CREST, and Japan Science and Technology Corporation in Tokyo, Japan; Shiki Okamoto, Tetsuya Shiuchi, and Yasuhiko Minokoshi of National Institute for Physiological Sciences in Okazaki, Japan; Masao Moroi and Kaoru Sugi of Toho University, Ohashi Hospital in Tokyo, Japan; Tetsuo Noda of the Japanese Foundation for Cancer Research and Tohoku University School of Medicine in Miyagi, Japan; Hiroyuki Ebinuma of Diagnostics Research Laboratories, Daiichi Pure Chemicals in Ibaraki, Japan; Yoichi Ueta of University of Occupational and Environmental Health in Fukuoka, Japan; Tatsuya Kondo and Eiichi Araki of Kumamoto University in Kumamoto, Japan; Osamu Ezaki of National Institute of Health and Nutrition in Tokyo, Japan; Yasuo Terauchi of Yokohama City University School of Medicine in Kanagawa, Japan.

This work was supported by a Grant-in-Aid for Creative Scientific Research from the Japan Society for the Promotion of Science (10NP0201), a grant from the Juvenile Diabetes Foundation International (1-2003-746), a Grant-in-Aid for the Development of Innovative Technology from the Ministry of Education, Culture, Sports, Science and Technology of Japan, Health Science Research grants (Research on Human Genome and Gene Therapy) from the Ministry of Health and Welfare, a grant for Promotion of Fundamental Studies in Health Science of the Organization for Pharmaceutical Safety and Research (to T. Kadowaki), a grant for Life & Socio-Medical Sciences from the Kanae Foundation, a grant from the Sankyo Foundation of Life Science, and a grant from Astellas Foundation for Research on Metabolic Disorders (to N.K.).

Kubota et al.: "Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake." Publishing in Cell Metabolism 6, 55-68, July 2007 DOI 10.1016/j.cmet.2007.06.003 http://www.cellmetabolism.org/

Source: Erin Doonan
Cell Press
 
 
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