Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California

 

Recent News and Articles on the Keywords: new + system + drug  Related to the article below (Last Update: 8/5/2008)

Toxic Drugs, Toxic System: Sociologist Predicts Drug Disasters
Science Daily (press release) -
"Recent changes in the system have only increased the proportion of new drugs with serious risks." According to a 1999 report for the Institute of Medicine, ...

Seattle Times
Icahn Calls Bristol Bid Too Low, Weighs ImClone Split (Update2)
Bloomberg -
Bristol-Myers, of New York, was the world's biggest seller of cancer medicine before its drug Taxol faced competition from cheaper copies in 2001. ...
Rates on short-term Treasury bills rise San Diego Union Tribune
Business Glance Salt Lake Tribune
The Evening Wrap Wall Street Journal
New York Times - MarketWatch
all 751 news articles »  IMCL - BMY - ATH:ASCO
FDA advisers must abide by new financial limits
The Associated Press -
Y., said the FDA's waiver policies had led to a broken system in which advisory panels were filled by experts with direct financial interests in the drugs ...
Bill Clinton Says Health System Fails High-Risk AIDS Patients
Bloomberg -
The foundation also has a staff of chemists who develop less expensive ways to manufacture drugs. For the drug efavirenz, sold by Bristol Myers-Squibb Co. ...
New drug treats West Nile virus in mice
Reuters -
The drug allows T cells of the immune system to cross the blood-brain barrier to combat the virus infecting the brain, Dr. Robyn S. Klein and associates ...

ABC News
Mary-Kate Olsen denies supplying Heath Ledger with drugs
guardian.co.uk, UK -
A masseuse employed by the 22-year-old former child star was the first person to find Ledger's body following the overdose at his New York apartment in ...
Official: Mary Kate Olsen silent on Ledger OD The Associated Press
Heath Ledger police want to question Mary Kate Olsen about his ... Times Online
Mary-Kate Olsen's Silence On Heath Ledger's Drug Probe AHN
InTheNews.co.uk - AHN
all 803 news articles »
Betamax rides again! Court OKs "remote storage DVRs," the gateway ...
Kansas City Star, MO -
With Monday's decision, old Betamax just got a new set of teeth. I wonder, though, if this ironically marks the beginning of the end (years from now) of the ...
Two new appointments announced
Mount Airy News, NC -
?We feel very fortunate to have quality leaders such as Mrs. Hodges in the Surry County School System,? said Dr. Ashley Hinson, superintendent. ...
DCS left boy with mom despite meth in his system
Indianapolis Star, United States -
Neglect and drug charges were filed against Blake. Tielking said her agency's general practice would be to remove a child who tests positive for ...
Research Exposes New Target For Malaria Drugs
Science Daily (press release) -
4, 2008) ? The malaria parasite has waged a successful guerrilla war against the human immune system for eons, but a study in this week's Journal of ...
Source: Google News

REGULATORS OF G-PROTEIN SIGNALLING AS NEW CENTRAL NERVOUS SYSTEM DRUG TARGETS -
RR Neubig, DP Siderovski - Nature Reviews Drug Discovery, 2002 - unc.edu
... the REGULATORS OF G-PROTEIN SIGNALLING AS NEW CENTRAL NERVOUS SYSTEM DRUG
TARGETS Richard R.Neubig* and David P.Siderovski ? G ...

New methods of drug delivery -
R Langer - Science, 1990 - sciencemag.org
... many drugs are delivered. IN THE LAST FEW YEARS, WE HAVE WITNESSED AN EXPLOSION
in research aimed at creating new drug delivery systems. ...

High-speed ultrasound volumetric imaging system. I. Transducerdesign and beam steering -
SW Smith, HG Pavy Jr, OT von Ramm, US Food, D Adm, … - Ultrasonics, Ferroelectrics and Frequency Control, IEEE …, 1991 - ieeexplore.ieee.org
... Food and Drug Administration, Rockville, MD 20857. ... In addition to scanning a pyramidal
volume, our new system can also be used to obtain any desired B-mode scan ...

Angiotensin II receptor antagonists: a new approach to blockade of the renin-angiotensin system. -
PM Kang, AJ Landau, RT Eberhardt, WH Frishman - Am Heart J, 1994 - ncbi.nlm.nih.gov
Am Heart J. 1994 May;127(5):1388-401. Click here to read Angiotensin II receptor
antagonists: a new approach to blockade of the renin-angiotensin system. ...

The price of innovation: new estimates of drug development costs -
JA DiMasi, RW Hansen, HG Grabowski - Journal of Health Economics, 2003 - Elsevier
... major components of the health care system since the ... that the discovery and development
of new drugs is a ... In the research-based drug industry, R&D decisions ...

[BOOK] Pharmacologic Analysis of Drug-Receptor Interaction
TP Kenakin - 1987 - Lippincott Williams & Wilkins, US
-

A new property of MCM-41: drug delivery system -
M Vallet-Regi, A Ramila, RP del Real, J Perez- … - Chem. Mater, 2001 - pubs.acs.org
... Copyright ? 2000 American Chemical Society A New Property of MCM-41: Drug Delivery
System. M. Vallet-Regi,* A. R?mila, RP del Real, and J. P?rez-Pariente. ...

[BOOK] Pharmacology -
HP Rang, MM Dale? - 1999 - harcourt-international.com
... One new chapter in the final section on Drug ... Absorption and distribution of drugs
8. Drug elimination and ... Chemical mediators and the autonomic nervous system 10 ...

A Broad Host Range Mobilization System for In Vivo Genetic Engineering: Transposon Mutagenesis in … -
R Simon, U Priefer, A Puehler - Bio/Technology, 1983 - nature.com
... Genetic engineering in vivo using translocatablc drug resistance elements ... broad-host
range DNA cloning system for gram ... Cold Spring Harbor Laboratory, New York. ...

The TIME CLOCK system: a new oral dosage form for fast and complete release of drug after a …
F POZZI, P FURLANI, A GAZZANIGA, SS DAVIS, IR … - Journal of controlled release, 1994 - cat.inist.fr
The TIME CLOCK system: a new oral dosage form for fast and complete release
of drug after a predetermined lag time. F POZZI, P FURLANI ...

Source: Google Scholar

Removable Tattoos, Innovative New Application For Drug Delivery System
In her Brown University laboratory, Edith Mathiowitz makes tiny particles coated in polymers. These microcapsules, some as small as the point of a pin, can carry medicines, genes, paints, pesticides -- any molecule that needs protection or controlled release.

Mathiowitz developed her technique as a drug delivery system, but her microcapsules are now being put to a very different use -- to make ink for the first permanent removable tattoo. Under a new intellectual property licensing agreement signed by Brown University and Freedom-2 Holdings Inc., the company has the right to make and sell their ink based on research Freedom-2 has funded in the Mathiowitz lab.
With Freedom-2 funding, Mathiowitz and her team have made microencapsulated beads filled with dyes. These beads are mixed with a solution to make Freedom-2 tattoo inks. The inks are safer than conventional products, free of heavy metals and other toxins. The inks can also be easily removed. A single laser treatment breaks the polymer beads, allowing the body to naturally expel the dye trapped inside. Currently, it takes about six or seven laser treatments to remove a tattoo using traditional inks.

"It's terrific that my technology has such a cool consumer application," Mathiowitz said. "My microencapsulation technique has other potential uses, particularly for making new medicines. Any fragile, bioactive molecule -- proteins, hormones, DNA -- can be coated so that it can be safely delivered to where it is needed in the body and still do its job once it gets there. There are enormous possibilities for drug delivery with this technology."

Microencapsulation, or suspending particles in biodegradable coatings, is widely used in manufacturing. The process is used to make products such as aspirin, plant food, stain remover, and cake mix. It's even used to make scratch-and-sniff perfume advertisements found in magazines: Scratch the treated paper and microbeads burst to release the scent.

Mathiowitz, a Brown professor of medical science and engineering, is known in the field for coming up with innovative coatings for molecules. The trick, she says, is understanding the substance that you're trying to protect. Knowing how a particular solid, liquid or gas behaves when exposed to heat, light, water or enzymes is critical to developing the correct coating method that will properly protect a substance until it can be released.

Microencapsulation requires a smorgasbord of scientific knowledge. Expertise in physics, physiology, biology and pharmacology is needed to do the work. Most of all, the work demands expertise in chemistry -- and the Mathiowitz lab reveals its chemistry roots. The room is filled with beakers and vats bubbling with solvents, polymers and dyes used to make Freedom-2 inks.
"Microencapsulation is a real science," she said, "and a real art."

It can also be big business. Microcapsules can be made to carry vaccines or human growth factors that can help the body regenerate bone, nerves or cartilage. Microcapsules can also carry controlled release drugs. Of the top 200 best-selling drugs in 2004, 11 compounds used oral controlled or extended release technologies and comprised sales of about $9 billion.

In 1997, Mathiowitz founded Spherics Inc., a pharmaceutical company that now makes drugs to treat nervous system disorders, gastrointestinal diseases and cancer.

"Encapsulation is a wonderful tool that can be used to benefit human health," Mathiowitz said. "We're just beginning to see the possibilities."



Source: Wendy Lawton
Brown University
 
 
Google
Web www.iconocast.com

Search inside Iconocast for the keyword you have in mind.

Iconocast has collected more than 50,000 articles and press releases on health and science.

These are current and most up to date press releases on the subject you are searching.

We collect current health and science press releases daily from more than 5000 research and health institutes. Here is an example : The elderberry way to perfect skin

We believe if you do search inside Iconocast, you will get better results than searching the web alone.

 
 
Continue News With: News3 ; News4 ; News5 ; News6 ; News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services.

 

Iconocast Home Page

Contact Iconocast

© 2003-07. ICONOCAST is a trademark of iconocast.com.