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Recent News and Articles on the Keywords: news + muscle + 0.17  Related to the article below (Last Update: 8/5/2008)

Active Versus Passive Recovery in the 72 Hours After a 5-km Race
United States Sports Academy Sports Journal, AL - Jul 8, 2008
Mean finishing times did not differ significantly (p = 0.17) between ACT (19:35 + 1.5 min) and baseline (19:41 + 1.7 min); nor was there significant ...
Low Salt Diet No Help for Asthma Control
MedPage Today, NJ - Jul 15, 2008
Adjusting for gender didn't appreciably change the findings (P=0.17 for interaction), suggesting a lack of a large, sex-specific effect of the low sodium ...
Source: Google News

Interactions of body fat and muscle mass with substrate concentrations and fasting insulin levels in … -
F Salomon, RC Cuneo, AM Umpleby, PH Sonksen - Clinical Science, 1994 - cs.portlandpress.com
... There was no correlation between lean body mass and fat mass (r = 0.17, not significant)
nor between muscle fibre types and fat mass or fat distribution. ...
-

Small event Ca2+ release: a probable precursor of Ca2+ sparks in frog skeletal muscle -
N Shirokova, E Rios - The Journal of Physiology, 1997 - Blackwell Synergy
... of amplitude less than 0.45 (a min = 0.79?2 ? 0.17) or half ... image of the calcium
spark in cardiac muscle cells. ... News in Physiological Science 3, 223? 227. ...

Catabolic enzyme activities in relation to premigratory fattening and muscle hypertrophy in the gray … -
RL Marsh - Journal of Comparative Physiology? B, 1981 - Springer
... by a modification of the procedures of Opie and News- holme (1967 ... does not change
significantly in the supracora- coideus muscle (Fig. 3B; r=0.17, P=0.41, n--25 ...

Magnetic resonance imaging of the rat Harderian gland. -
A Sbarbati, L Calderan, E Nicolato, P Marzola, E … - Journal of Anatomy, 2002 - pt.wkhealth.com
... Advanced Search. Ovid News. Learn about Ovid?s new research content and products ...
after injection of AMI-25, significantly different from the muscle (0.17 ? 0.10 ...

Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes -
DE Kelley, J He, EV Menshikova, VB Ritov - Diabetes, 2002 - Am Diabetes Assoc
... subjects and highest in the lean volunteers (lean 0.95 ? 0.17, obese 0.76 ... As measured
by electron microscopy, skeletal muscle mitochondria were smaller in ...

Impaired nutritive skeletal muscle blood flow in patients with chronic renal failure -
JR Bradley, JR Anderson, DB Evans, AJ Cowley - Clin Sci, 1990 - cs.portlandpress.com
... ml min-1 100 ml-1 in the patients and 1.43 (SEM 0.17) ml min-1 ... 4. Skeletal muscle
biopsies from eight haemodialysis patients were studied by histochemistry and ...

… Nucleotides and Polyphosphoinositide Hydrolysis, Protein Kinases, and Contraction in Smooth Muscle … -
AA Abdel-Latif - Experimental Biology and Medicine, 2001 - SEBM
... observed with an IC 50 value of 0.17 ?M (Fig ... C isoforms, cytoskeletal organization,
and vascular smooth muscle differentiation ... News Physiol Sci 15:41?45, 2000 ...

Synthetic muscle promoters: activities exceeding naturally occurring regulatory sequences -
X Li, EM Eastman, RJ Schwartz, R Draghia-Akli - Nature Biotechnology, 1999 - nature.com
... 12 was tested over a 96 h time course during primary avian muscle cell myogenesis ...
g protein at 96 h). SK448 expression increased only after 48 h (0.17 0.016 x ...

Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice -
B Li, LA Nolte, JS Ju, DH Han, T Coleman, JO … - Nature Medicine, 2000 - nature.com
... Epitrochlearis muscle, but not soleus muscle, was smaller in Ucp-L mice. ... Resting
whole-body metabolic rate in fat-fed males was 10.38 0.17 ml/h/g 0.75 for wild ...

Vascular smooth muscle: aerobic glycolysis linked to sodium and potassium transport processes -
RJ Paul, M Bauer, W Pease - Science, 1979 - sciencemag.org
... News 32, 364 (1972); RK Washino, KG Whitesell, E, J ... K+restored 1.18 ? 0.17 (6) 1.04 ?
0.09 (7) -0.02 ? 0.07 (6) ... Vascular Smooth Muscle: Aerobic Glycolysis ...

Source: Google Scholar

Muscle Wasting More Bad News For Smokers
Researchers at The University of Nottingham have got more bad news for smokers. Not only does it cause cancer, heart attacks and strokes but smokers will also lose more muscle mass in old age than a non-smoker. The effect of this predisposes smokers to an accelerated decline in physical function and loss of independence.

Research has already established that smokers tend to have a lower muscle mass than non-smokers but no one has been able to explain why.
Now, Michael Rennie, a Professor of Clinical Physiology, and Dr Philip Atherton, a Research Fellow, both from the university's School of Graduate Entry Medicine and Health at Derby, have, with collaborators in Denmark and the USA, discovered that smoking impairs the day to day upkeep of muscle. Their research shows that smoking is likely to speed up a condition known as sarcopenia -- the loss of muscle mass with ageing which is linked to poor balance, gait speed, falls, and fractures.

Sixteen people took part in the study which was part funded by the Biotechnology and Biological Sciences Research Council. The men and woman in their mid sixties were selected because of their similar lifestyles in terms of alcohol consumption and physical activity. They were all considered to be healthy, with no symptoms of lung disease. They were studied in two equal groups: heavy smokers, who had smoked at least a pack of 20 cigarettes a day for at least 20 years: and non-smokers.

To measure the synthesis of muscle protein they were given an intravenous infusion of blood with a tagged amino acid (one of the building blocks of protein). Samples of muscle were taken from their thighs before and after the infusion to follow how much had "stuck" in muscle protein. This measured the rate of synthesis of muscle protein which contributes to the daily maintenance of the muscle mass. The researchers found that it was substantially less in smokers than non-smokers.

During extensive studies, carried out in collaboration with Washington University, St Louis and Copenhagen University, Professor Rennie and Dr Atherton discovered that the amounts of myostatin, a muscle growth inhibitor and MAFbx enzyme, which breaks down muscle protein, were higher in smokers than non-smokers.
Dr Philip Atherton said: "From our tests, we can conclude that smoking slows the muscle protein synthesis machinery -- probably impairing day to day upkeep of muscle. We are all well aware of the ill affects of smoking on the lungs but our study reveals yet another cause of ill-health associated with smoking. Hopefully the UK smoking ban will encourage people to quit while they are still young, helping them to keep in good health in later life".

Their research was presented by Dr Atherton at Life Sciences 2007. This is the first joint meeting of the Biochemical Society, the British Pharmacological Society and The Physiological Society. .

The full paper describing their work has been published on line in American Journal of Physiology.

The University of Nottingham is Britain's University of the Year (The Times Higher Awards 2006). It undertakes world-changing research, provides innovative teaching and a student experience of the highest quality. Ranked by Newsweek in the world's Top 75 universities, its academics have won two Nobel Prizes since 2003. The University is an international institution with campuses in the United Kingdom, Malaysia and China.

More information can be found at http://www.lifesciences2007.org/

Source: Professor Michael Rennie
University of Nottingham
 
 
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