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Recent News and Articles on the Keywords: web + 0.09 + 602  Related to the article below (Last Update: 8/5/2008)

Motorola Announces Second-Quarter Financial Results
Earthtimes (press release), UK - Jul 31, 2008
The conference call will be web-cast live with audio and slides at http://www.motorola.com/investor. Definitions * Net Cash equals Total Cash minus Notes ...MOT
Wachovia Details 2nd Quarter Loss; Outlines Initiatives to ...
PR Newswire (press release), NY - Jul 22, 2008
Web cast Instructions: To gain access to the web cast, which will be "listen-only," go to Wachovia.com/investor and click on the link "Wachovia Second ...WB
Source: Google News

Styptic device -
WK Dunshee? - US Patent 4,233,976, 1980 - freepatentsonline.com
... Primary Class: 604/309. Other Classes: 602/48, 602/45. International Classes:
A61F13/00; A61L15/18; A61F13/15; A61L15/16 ... The web contained 0.09 gram of ...

Characteristics of streaming media stored on the Web -
M Li, M Claypool, R Kinicki, J Nichols - ACM Transactions on Internet Technology (TOIT), 2005 - portal.acm.org
... 602 ? M. Li et al. ... Thus, the percentage of audio and video objects stored on the
Web has increased more than five-fold from about 0.09% in 1997 to ...

[PDF] … particulate material and microbes by resuspension and their contribution to the planktonic food web -
MEP SERIES - MARINE ECOLOGY PROGRESS SERIES, 1990 - int-res.com
... Prog. Ser. Sediment-to-water fluxes of particulate material and microbes by
resuspension and their contribution to the planktonic food web Sam C. Wainright* ...

602. Induction of Tolerance to Human Factor VIII after Neonatal Gene Transfer of a Retroviral Vector … -
L Xu, M Mei, ME Haskins, K Cullen, KP Ponder - Molecular Therapy, 2005 - nature.com
... 602. Induction of ... antibodies. Average antibody levels for the group were
0.09|[plusmn]|0.03 mg/ml and 10|[plusmn]|4 BU/ml. These ...

Bioaccumulation of polychlorinated biphenyls (PCBs) in the marine pelagic food web, based on a … -
GC Hording, RJ LeBlanc, WP Vass, RF Addison, BT … - Marine Chemistry, 1997 - Elsevier
... The structure and dy- namics of the pelagic food web were described earlier (Hargrave
et ... 5.4*os Dieldrin 0.20 * 0.02 0.45 50.07 ND p,p?-DDT 0.09 + 0.02 0.05 ...

[PDF] A statistical analysis of the web presences of European life sciences research teams -
F Barjak, M Thelwall - Journal of the American Society for Information Science and …, 2008 - ticinoricerca.ch
1 A statistical analysis of the web presences of European life ... Abstract Web links
have been used for around ten years to explore the online impact of academic ...
-

[PDF] DONNER MINERALS LTD. -
DM LTD - Vancouver, British Columbia, Canada, Vanguard Review, March, 2002 - donner-minerals.com
... V6B 5J3 Telephone: (604) 683-0564 Fax: (604) 602-9311 or ... 8311 E-mail: donner@bed-
rock.com or Web: http://www ... 267.88 268.68 0.80 Gneiss 1.57 0.6 0.09 20.20 2.98 ...

… Zealand stream communities: effects on species composition, functional organisation, and food-web -
RM Thompson, CR Townsend - New Zealand Journal of Marine and Freshwater Research, 2004 - rsnz.org
... in terms of both distribution of biomass across species and food-web structure were ...
0.09 ... 602 New Zealand Journal of Marine and Freshwater Research, 2004, Vol. ...

[PDF] Daphnids: Keystone species for the pelagic food web structure and energy flow.-A body size-related … -
U Gaedke, D Straile - Arch. Hydrobiol. Spec. Iss. Advanc. Limnol, 1998 - ub.uni-konstanz.de
... Daphnids: Keystone species for the pelagic food web ... This study focuses on the effects
of daphnids on energetical properties of the food web, Page 3. ...

Prolonged diatom blooms and microbial food web dynamics: experimental results from an Arctic polynya -
C Lovejoy, L Legendre, NM Price - Aquatic Microbial Ecology, 2002 - int-res.com
... the standing stocks and net production of other micro- bial food web constituents,
specifically ... T s+ 6 NEW 0.80 (0.47) 1.60 (0.14) 0.146 (0.036) 0.156 (0.09) ...

Source: Google Scholar

Contact: Brooke Grindlinger
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation

Mucins stand guard against gut infections

Mucins are large proteins that are secreted on the surface of the gut, and while long regarded as having a role as a barrier to mucosal infection, data to support this theory have been lacking. In a study appearing online on July 19 in advance of publication in the August print issue of the Journal of Clinical Investigation, Michael McGuckin and colleagues from the University of Queensland, Australia, show that cell surface mucin 1 (Muc1) plays a critical role in protecting the mucosal lining of the gut from bacterial infection.

These authors orally infected mice with the bacterial pathogen Campylobacter jejuni (a common cause of diarrhea) and found that 1 week after infection this organism could be detected in the organs of the vast majority of mice lacking Muc1, but never in mice with intact Muc1.

Although this organism was able to enter the gastrointestinal epithelial cells lining the gut of both Muc1-deficient and Muc1-intact mice, intestinal damage was more common in Muc1-deficient animals, and the authors determined that the prevention of the spread of infection was exclusively due to Muc1 on the surface of gut epithelial cells. This is believed to be the first study in animals to demonstrate that cell surface mucins are a critical component of mucosal defense, and the role of these proteins in epithelial infections and inflammatory disease should be further examined.

###

TITLE: MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

AUTHOR CONTACT:
Michael A. McGuckin
University of Queensland, South Brisbane, Queensland, Australia.
Phone : 61-7-3840-2568; Fax: 61-7-3840-2550; E-mail: mmcguckin@mmri.mater.org.au

View the PDF of this article at: https://www.the-jci.org/article.php?id=26705

 
 
 
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