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Recent News and Articles on the Keywords: ankylosing + spondylitis + disease  Related to the article below (Last Update: 8/5/2008)

Short fuse for pain
Irish Times, Ireland - Jul 21, 2008
It is still not known why ankylosing spondylitis, a chronic inflammatory disease, affects more men than women, writes Ciar?n Brennan . ...
Medical Edge: New drug promising for type of arthritis
Post-Bulletin, MN - Jul 28, 2008
But one new class of drugs looks particularly promising for both relieving symptoms and treating the disease's underlying cause. Ankylosing spondylitis is a ...
More News related to Press Releases
StreetInsider.com (subscription), MI - Jul 15, 2008
People with an immune disease, such as rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis, ...AMGN - WYE
Provincial drug funding puts arthritis victim back in action
CHEK News, Canada - Jul 20, 2008
Ankylosing spondylitis, the disease that hit Harrington, is a painful degenerative, inflammatory arthritis that mostly afflicts the spine. ...

The Gauntlet
Too Old for Tampons: Mick Mars
The Gauntlet, CA - Jul 22, 2008
It recently came out that Motley Crue guitarist, Mick Mars, suffers from Ankylosing Spondylitis. This is a disease that has affected his joints and bones. ...
M?TLEY CR?E Guitarist's 24-Year-Old Swiss Girlfriend: 'I Am ...
Blabbermouth.net, NY - Jul 20, 2008
"I am totally in love," she said about the guitarist who suffers from the degenerative bone disease ankylosing spondylitis. "[He is] the man of my life. ...

BBC Sport
Woosnam hails new lease of life
BBC Sport, UK - Jul 9, 2008
... post-viral fatigue syndrome Myalgic Encephalomyelitis, Woosnam has also been battling the painful, progressive rheumatic disease Ankylosing Spondylitis. ...
Datazoom's 'Research Smarts' Provides Insights for Healthcare ...
Compliance Home, IA - Jul 10, 2008
Researchers specialized in diseases such as Lupus, Hepatitis, Ankylosing Spondylitis, Scleroderma and other relatively obscure diseases have found it ...
Wyeth Reports Earnings Results for the 2008 Second Quarter and ...
FOXBusiness - Jul 23, 2008
... chronic inflammatory diseases, including rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and psoriasis. ...WYE - OTC:CMTX
She's watching her weights
Boston Globe, United States - Jul 30, 2008
She also has ankylosing spondylitis, an autoimmune disorder that causes pain and discomfort in the joints. Through all this, Robinson said, the toughest ...
Source: Google News

… to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease -
S Garrett, T Jenkinson, LG Kennedy, H Whitelock, P … - J Rheumatol, 1994 - ncbi.nlm.nih.gov
1994 Dec;21(12):2286-91. A new approach to defining disease status in ankylosing
spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. ...

… in ankylosing spondylitis: is a combination of variables (Bath Ankylosing Spondylitis Disease -
A Calin, JP Nakache, A Gueguen, H Zeidler, H … - Rheumatology, 1999 - Br Soc Rheumatology
... Defining disease activity in ankylosing spondylitis: is a combination of variables
(Bath Ankylosing Spondylitis Disease Activity Index) an appropriate ...

Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre … -
J Braun, J Brandt, J Listing, A Zink, R Alten, W … - The Lancet, 2002 - Elsevier
... for ankylosing spondylitis, 19 and who had severe active disease that was defined
by a Bath ankylosing spondylitis disease activity index (BASDAI) 20 of 4 or ...

Successful treatment of active ankylosing spondylitis with the anti?tumor necrosis factor … -
J Brandt, H Haibel, D Cornely, W Golder, J … - Arthritis Rheum, 2000 - doi.wiley.com
... Values are the median (range). BASDAI Bath Ankylosing Spondylitis Disease
Activity Index; BASFI Bath AS Functional Index; BASMI ...

… rate and C-reactive protein in assessment of disease activity in ankylosing spondylitis. -
A Spoorenberg, D van der Heijde, E de Klerk, M … - J Rheumatol, 1999 - ncbi.nlm.nih.gov
... activity was: physician and patient assessment of disease activity on a visual analog
scale (VAS) and the Bath Ankylosing Spondylitis Disease Activity Index ...

Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment. -
MA Brown, LG Kennedy, AJ MacGregor, C Darke, E … - Arthritis Rheum, 1997 - ncbi.nlm.nih.gov
... genetic and environmental factors in susceptibility to ankylosing spondylitis (AS ...
examinations were performed to establish diagnoses, and disease severity was ...

… functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis -
A Calin, S Garrett, H Whitelock, LG Kennedy, JO' … - J Rheumatol, 1994 - ncbi.nlm.nih.gov
... specific for the disease or have not been adequately validated. As a result of this
deficiency we developed the Bath Ankylosing Spondylitis Functional Index ...

Recombinant human tumor necrosis factor receptor (etanercept) for treating ankylosing spondylitis -
JC Davis, D van der Heijde, J Braun, M Dougados, J … - Arthritis Rheum, 2003 - doi.wiley.com
... the BASFI (11); and inflammation was measured as the average of the scores for the
last 2 questions on the Bath Ankylosing Spondylitis Disease Activity Index ...

Treatment of Ankylosing Spondylitis by Inhibition of Tumor Necrosis Factor {alpha} -
JD Gorman, KE Sack, JC Davis Jr - New England Journal of Medicine, 2002 - content.nejm.org
... and tissue inhibitors of metalloproteinases in ankylosing spondylitis: MMP-3 is
a reproducibly sensitive and specific biomarker of disease activity. ...

… between ankylosing spondylitis, psoriatic arthritis, Reiter's disease, the intestinal arthropathies …
JM Moll, I Haslock, IF Macrae, V Wright - Medicine (Baltimore), 1974 - ncbi.nlm.nih.gov
1974 Sep;53(5):343-64. Associations between ankylosing spondylitis, psoriatic arthritis,
Reiter's disease, the intestinal arthropathies, and Behcet's syndrome. ...

Source: Google Scholar
 

Ankylosing Spondylitis (Marie-Strumpell Disease)

Ankylosing spondylitis (AS) is a condition in which the joints and ligaments of the back become inflamed.

Symptoms

AS causes stiffness, usually starting in the lower back. Over time it may spread into the upper spine, causing joints and bones to become fused. This makes the spine rigid.

About a third of all persons with AS may have symptoms that affect other parts of the body besides the joints and ligaments, including ones affecting the heart and blood vessels.

Causes and Risk Factors

This condition tends to be inherited. It most commonly occurs in men between the ages of 16 and 30, but can also occur in women.

Article continues below and (thank you)

 
Diagnosis

Some blood tests can help identify that the symptoms are those of AS. However, X-rays must confirm the diagnosis.

Some changes caused by AS only begin appearing over a period of 10 years or so.

Treatment

The earlier AS is treated, the better. Once joints fuse (become joined together and rigid), mobility won't completely return even with treatment. Drugs may relieve the pain it causes.

Usually, AS is treated with:

  • Physical therapy to reduce pain and stiffness and to bring back mobility
  • Drug therapy. This includes over-the-counter drugs that relieve pain (such as aspirin, ibuprofen, naproxen and piroxicam). It can also include drugs that modify rheumatic diseases (such as sulfasalazine and methotrexate and corticosteroids like prednisone. Researchers are also looking at promising, new drugs, such as tumor necrosis factor (TNF) blockers etanercept and infliximab.
 
 
 
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